Unlock instant, AI-driven research and patent intelligence for your innovation.

A pharmaceutical composition for treating senile dementia

A technology for Alzheimer's disease and composition, which is applied in the field of medicine, can solve the problems of high treatment cost, long drug effect time, and large side effects, and achieve the effect of improving the condition, low toxicity and side effects, and simple cost

Active Publication Date: 2015-08-12
QIDONG CIYT JIULONG SHUNZHOU TOY FACTORY
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to solve the shortcomings of existing drugs for treating neurodegenerative diseases in clinical application, especially the defects of large side effects and high treatment costs in drugs for treating Alzheimer's disease, the present invention provides a drug with long drug effect time, low price and less side effects. a pharmaceutical composition

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A pharmaceutical composition for treating senile dementia
  • A pharmaceutical composition for treating senile dementia
  • A pharmaceutical composition for treating senile dementia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1 Pharmaceutical composition tablet preparation

[0026] Prescription: risperidone 0.1g, asiaticosides 5g, starch 25g, dextrin 35g, low-substituted hydroxypropyl cellulose 5g, 60% ethanol, 1g magnesium stearate.

[0027] Preparation process: Weigh the prescription amount of risperidone, asiaticoside, starch, dextrin and low-substituted hydroxypropyl cellulose and mix them evenly. Take another appropriate amount of 60% ethanol, add it to the mixed powder, mix it evenly to make a soft material, granulate it through a 16-mesh sieve, and dry it below 60°C. After drying, use an 18-mesh sieve to carry out granulation, sieve out the fine powder in the dry granules, mix with the sieved magnesium stearate, and then mix with the dry granules evenly, and press into tablets to obtain the product.

Embodiment 2

[0028] Example 2 Preparation of Risperidone Tablets

[0029] Prescription: 25g of risperidone, 200g of asiaticosides, 180g of microcrystalline cellulose, 15g of hydroxypropyl cellulose, appropriate amount of 8% starch slurry, and 1.5g of magnesium stearate. Preparation process: Weigh the prescribed amount of risperidone, asiaticoside, microcrystalline cellulose and hydroxypropyl cellulose and mix evenly. Take another appropriate amount of 8% starch slurry solution, add it to the mixed powder, mix evenly to make soft material, pass through a 16-mesh sieve to granulate, and dry below 60°C. After drying, use an 18-mesh sieve to carry out granulation, sieve out the fine powder in the dry granules, mix with the sieved magnesium stearate, and then mix with the dry granules evenly, and press into tablets to obtain the product.

Embodiment 3

[0030] Example 3 Preparation of Risperidone Tablets

[0031] Prescription: 50g of risperidone, 10g of asiaticosides, 25g of starch, 35g of dextrin, 5g of low-substituted hydroxypropyl cellulose, appropriate amount of 60% ethanol, and 1g of magnesium stearate.

[0032] Preparation process: Weigh the prescription amount of risperidone, asiaticoside, starch, dextrin and low-substituted hydroxypropyl cellulose and mix them evenly. Take another appropriate amount of 60% ethanol, add it to the mixed powder, mix it evenly to make a soft material, granulate it through a 16-mesh sieve, and dry it below 60°C. After drying, use an 18-mesh sieve to carry out granulation, sieve out the fine powder in the dry granules, mix with the sieved magnesium stearate, and then mix with the dry granules evenly, and press into tablets to obtain the product.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition for treating senile dementia, and belongs to the technical field of medicines. In order to reduce the toxicity and side effects of chemical treatment medicaments against the senile dementia, the invention requests to protect the pharmaceutical composition for treating the senile dementia, the pharmaceutical composition can further comprise galanthamine and borneol, and the two pharmaceutical ingredients can be used for further enhancing the treatment effect of the pharmaceutical composition against the senile dementia. The pharmaceutical composition comprises risperidone and asiaticosides, and when the pharmaceutical composition is used for treating the senile dementia, the curative effect is exact, side effects are low, and the medical application prospects are broad.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating senile dementia. Background technique [0002] Neurodegenerative disease is a disease state in which cells and neurons of the brain and spinal cord are lost. The brain and spinal cord are made up of neurons that have different functions, such as controlling movement, processing sensory information, and making decisions. Cells in the brain and spinal cord generally do not regenerate, so excessive damage can be devastating and irreversible. Neurodegenerative diseases are caused by the loss of neurons or their myelin sheath, which worsens over time to lead to dysfunction. Neurodegenerative diseases are divided into two groups according to their phenotype: one group affects movement, such as cerebellar ataxia. A class of disorders that affect memory and related dementias. Alzheimer's disease, also known as Alzheimer's disease...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/23A61P25/28A61K31/519A61K31/55A61K31/045
Inventor 于桂霞
Owner QIDONG CIYT JIULONG SHUNZHOU TOY FACTORY