A pharmaceutical composition for regulating blood fat and its preparation method

A composition and a technology for regulating blood lipids are applied in the field of medicine to achieve the effect of small dosage and lowering level

Active Publication Date: 2016-04-13
JINAN DAYI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] At present, there are no related reports about the combination of Gynostemma pentaphyllum extract, Panax notoginseng extract, turmeric extract, Apocynum extract, and grape extract that have the effect of regulating blood lipids

Method used

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  • A pharmaceutical composition for regulating blood fat and its preparation method
  • A pharmaceutical composition for regulating blood fat and its preparation method
  • A pharmaceutical composition for regulating blood fat and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] The preparation of embodiment 1 Gynostemma pentaphyllum extract

[0065] After washing the Gynostemma pentaphyllum medicinal material, add 4 times the amount of water to extract twice, the first time is 2 hours, the second time is 1.5 hours, filter, the filtrate is concentrated, and the concentrated solution is diluted with 0.5 times the pure water of the concentrated solution. Separation by centrifugation (12000 rev / min), followed by resin adsorption, elution with 4 times the amount of ethanol of the centrifugation solution, collection of the eluent, recovery of ethanol, spray drying to obtain the Gynostemma pentaphyllum extract.

[0066] The main active ingredient of the obtained Gynostemma pentaphyllum extract is total saponins of Gynostemma pentaphyllum with a content of 20%.

Embodiment 2 10

[0067] The preparation of embodiment 2 Panax notoginseng extract

[0068] After washing the notoginseng medicinal material, put it into an extraction tank and add 4 times the amount of ethanol water to extract twice, the first time for 2 hours, the second time for 1.5 hours, filter, vacuum concentrate the filtrate to recover ethanol, spray dry or vacuum dry to obtain Panax notoginseng extract.

[0069] The main active ingredient of the obtained Panax notoginseng extract is the total saponins of Panax notoginseng, with a content of 6%

Embodiment 3

[0070] The preparation of embodiment 3 turmeric extract

[0071] Take the turmeric medicinal material and wash it, put it into the extraction tank and add 4 times the amount of ethanol water to extract twice, the first time is 2 hours, the second time is 1.5 hours, filter, the filtrate is concentrated in vacuum to recover ethanol, spray dry or vacuum dry to get turmeric Extract.

[0072] The main active ingredient of the obtained turmeric extract is curcumin, and the content is 1%.

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PUM

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Abstract

The invention belongs to the technical field of medicines, and in particular relates to a medicinal composition for regulating blood fat and a preparation method thereof. The medicinal composition comprises the following components in parts by weight: 30-100 parts of gynostemma pentaphylla extract, 30-100 parts of pseudo-ginseng extract, 40-100 parts of turmeric extract, 30-100 parts of apocynum venetum extract, 100-180 parts of grape extract. The invention also provides a preparation of the medicinal composition, a preparation method thereof and application of the preparation in preparing a medicine for regulating blood fat.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for regulating blood lipid and a preparation method thereof. Background technique [0002] Hyperlipidemia refers to a disease in which one or more lipids in plasma are higher than normal due to abnormal fat metabolism or transport. It mainly refers to hypercholesterolemia and hypertriglyceridemia. Dyslipidemia refers to the increase of total cholesterol, low-density lipoprotein cholesterol and triglyceride in the blood, while the decrease of high-density lipoprotein cholesterol. Long-term clinical studies have found that hyperlipidemia is an important risk factor for atherosclerosis, and an independent and important risk factor for stroke, coronary heart disease, myocardial infarction, and sudden cardiac death. [0003] Gynostemma Pentaphyllum (Thumb.) Makino, also known as Aescin, is a perennial herbaceous vine. Bitter in the mouth; S...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P3/06
Inventor 王德奎
Owner JINAN DAYI TECH
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