Compound preparation containing lutein ester and preparation method thereof

A technology of compound preparation and lutein ester, applied in the field of prevention or treatment of age-related macular degeneration and relief of visual fatigue, compound preparation containing lutein ester and its preparation, can solve the problem of low bioavailability and high processing cost , poor stability and other issues, to achieve high bioavailability, prevent damage, and protect the retina

Active Publication Date: 2014-04-23

ZHEJIANG UNIV OF TECH

2 Cites 16 Cited by

AI-Extracted Technical Summary

Problems solved by technology

This technical scheme adopts lutein etc. as the main functional substances, and its disadva...

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Abstract

The invention provides a compound preparation containing lutein ester, which is taken orally. The compound preparation comprises the following raw materials in parts by weight: 0.3-10.1 parts of lutein, 0-12.2 parts of lycopene, 0.1-18.7 parts of beta-carotene, 0-6.3 parts of vitamin B1, 0-7.2 parts of vitamin B2, 12.6-33.8 parts of vitamin C, 0-10.6 parts of vitamin E, 18.15-42.75 parts of zinc gluconate, 0-126.6 parts of wolfberry extract and 0-89.5 parts of cassia seed powder. The compound preparation containing lutein ester provided by the invention is scientific and reasonable in prescription composition and content collocation, innovative and feasible in process, and both capable of reducing the raw material cost, and greatly improving the bioavailability and biological safety for taking, generating synergistic interaction, significantly preventing and treating AMD disease and helping to alleviate visual fatigue, so that the market application prospect is wide.

Application Domain

Senses disorderHydrocarbon active ingredients +2

Technology Topic

AdemetionineB1 Vitamin +16

Image

Examples

Experimental program(13)

Example Embodiment

[0060] Example 1: Lutein ester capsules containing lycopene, wolfberry extract and cassia seed powder

[0061] Prescription (based on 200mg total component content of each drug):

[0062]

[0063]

[0064] Preparation:

[0065] The above prescription amount of lutein ester, lycopene, wolfberry extract, zinc gluconate, vitamin C and starch are fed in 10,000 times the amount, and they are passed through an 80-mesh sieve to obtain fine powder, which is then mixed with cassia seed powder. , Adding starch slurry to make soft material, granulating, drying in an oven at 60°C; adding magnesium stearate (magnesium stearate has been pre-passed through an 80-mesh sieve), mixing uniformly, sizing, and filling into capsules.

Example Embodiment

[0066] Example 2: Lutein ester capsules containing lycopene, wolfberry extract and cassia powder

[0067] Prescription (based on 200mg total component content of each drug):

[0068]

[0069] Preparation:

[0070] In this example, sucrose was used as diluent, low-substituted hydroxypropyl cellulose was used as disintegrant, talc was used as glidant, and water was used as binder. Each component of the prescription was passed through a 100-mesh sieve and granulated at 70°C. Dry in an oven, and the other preparation methods are the same as in Example 1.

Example Embodiment

[0071] Example 3: Lutein ester capsules containing lycopene, wolfberry extract and cassia seed powder

[0072] Prescription (based on 200mg total component content of each drug):

[0073]

[0074] Preparation:

[0075] In this example, glucose was used as diluent, sodium carboxymethyl starch was used as disintegrant, sodium lauryl sulfate was used as glidant, and ethanol was used as binder. Each component of the prescription was passed through an 80-mesh sieve. Dry in an oven at 50°C, and the other preparation methods are the same as in Example 1.

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PUM

Property	Measurement	Unit
Particle size	1.0 ~ 75.0	µm
tensile		MPa
Particle size		Pa
strength	10

Description & Claims & Application Information

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Classification and recommendation of technical efficacy words

Good treatment effect

Preparation method of active antibacterial composite coating on surface of titanium and titanium alloy medical instrument

ActiveCN102677125AImprove antibacterial propertiesGood treatment effectSurface reaction electrolytic coatingMicro arc oxidationAntibacterial coating

Owner:NORTHWEST INSTITUTE FOR NON-FERROUS METAL RESEARCH

Chinese medicinal composition for treating pain and preparation process thereof

InactiveCN1970073AGood treatment effectWide range of applicationsHeavy metal active ingredientsOrganic active ingredientsAdemetionineAchyranthes

Owner:孔祥权

Compound preparation containing lutein ester and preparation method thereof

AI-Extracted Technical Summary

Problems solved by technology

Abstract

Image

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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