Compound preparation containing lutein ester and preparation method thereof
A technology of compound preparation and lutein ester, applied in the field of prevention or treatment of age-related macular degeneration and relief of visual fatigue, compound preparation containing lutein ester and its preparation, can solve the problem of low bioavailability and high processing cost , poor stability and other issues, to achieve high bioavailability, prevent damage, and protect the retina
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[0060] Example 1: Lutein ester capsules containing lycopene, wolfberry extract and cassia seed powder
[0061] Prescription (based on 200mg total component content of each drug):
[0062]
[0063]
[0064] Preparation:
[0065] The above prescription amount of lutein ester, lycopene, wolfberry extract, zinc gluconate, vitamin C and starch are fed in 10,000 times the amount, and they are passed through an 80-mesh sieve to obtain fine powder, which is then mixed with cassia seed powder. , Adding starch slurry to make soft material, granulating, drying in an oven at 60°C; adding magnesium stearate (magnesium stearate has been pre-passed through an 80-mesh sieve), mixing uniformly, sizing, and filling into capsules.
Example Embodiment
[0066] Example 2: Lutein ester capsules containing lycopene, wolfberry extract and cassia powder
[0067] Prescription (based on 200mg total component content of each drug):
[0068]
[0069] Preparation:
[0070] In this example, sucrose was used as diluent, low-substituted hydroxypropyl cellulose was used as disintegrant, talc was used as glidant, and water was used as binder. Each component of the prescription was passed through a 100-mesh sieve and granulated at 70°C. Dry in an oven, and the other preparation methods are the same as in Example 1.
Example Embodiment
[0071] Example 3: Lutein ester capsules containing lycopene, wolfberry extract and cassia seed powder
[0072] Prescription (based on 200mg total component content of each drug):
[0073]
[0074] Preparation:
[0075] In this example, glucose was used as diluent, sodium carboxymethyl starch was used as disintegrant, sodium lauryl sulfate was used as glidant, and ethanol was used as binder. Each component of the prescription was passed through an 80-mesh sieve. Dry in an oven at 50°C, and the other preparation methods are the same as in Example 1.
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