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Preparation method of squalene and tea polyphenols composition liquid proliposome and its application in base reduction and harm reduction

A technology for proliposomes and tea polyphenols, applied in the field of chemistry, can solve the problems such as the preparation technology and application reports of liquid proliposomes that have not been seen, and achieve the effects of large surface area, high dispersion and large specific surface area.

Inactive Publication Date: 2015-08-19
SOUTH CHINA AGRI UNIV +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] There is no report on processing these free radical scavengers into liquid proliposomes and scientifically placing them in hookah cigarette holders to scavenge gaseous free radicals (reduced radicals), let alone studies based on the enhancement of squalene and tea polyphenols. Preparation technology and application report of liquid proliposome with effective composition

Method used

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  • Preparation method of squalene and tea polyphenols composition liquid proliposome and its application in base reduction and harm reduction

Examples

Experimental program
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Effect test

Embodiment 1

[0049] Each component was prepared according to the following parts by mass: 10 grams (g) of hydrogenated lecithin; squalene (Shanghai Xinran Biotechnology Co., Ltd., with a content greater than 96.0%, the same as the following examples. But this does not limit the present invention, Those skilled in the art can use 5 grams (g) of squalene from other sources; Tea polyphenols (Ningbo Youjie Chemical Co., Ltd., content greater than 98.0%, the same as the following examples. But this does not limit the present invention, the present invention Those skilled in the art can use 20 grams (g) of tea polyphenols from other sources); 10 grams (g) of glycerol; 8 grams (g) of hydroxymethyl starch, and 47 grams (g) of water.

[0050] The preparation steps are:

[0051] S1. Dissolving the composition of hydrogenated lecithin, squalene and tea polyphenols in glycerol to obtain a mixed system;

[0052] S2. Homogenize the mixed system obtained in S1 at high speed to make it fully mixed to obt...

Embodiment 2

[0055] The preparation steps are the same as in Example 1. Weigh 10 grams of hydrogenated soybean lecithin, 10 grams of squalene, 15 grams of tea polyphenols dissolved in 10 grams of glycerol, homogenize at high speed to make it fully mixed, then add 8 grams of hydroxyethyl starch dissolved in 47 grams of water The aqueous solution is stirred evenly to form a stable particle suspension, and the liquid proliposome containing the antioxidant squalene and tea polyphenol composition is obtained.

Embodiment 3

[0057] The preparation steps are the same as in Example 1. Weigh 10 grams of hydrogenated soybean lecithin, 15 grams of squalene, 10 grams of tea polyphenols dissolved in 10 grams of glycerin, homogenize at high speed to make it fully mixed, then add 8 grams of hydroxymethyl starch dissolved in 47 grams of water The aqueous solution is stirred evenly to form a stable particle suspension, and the liquid proliposome containing the antioxidant squalene and tea polyphenol composition is obtained.

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Abstract

The invention discloses a preparation method and radical reduction and harm reduction application of squalene and tea polyphenol composition liquid proliposome. The liquid proliposome is prepared from 7-10 parts of hydrogenated phospholipid, 8-12 parts of stabilizer, 10-15 parts of surfactant, 25-45 parts of squalene and tea polyphenol composition and the balance water. The liquid proliposome is filled into a hollow cylinder with waterproof dustproof gas-permeable membranes at two ends, and the hollow cylinder is disposed inside a cigarette filter in the forming process of a cigarette filter rod to obtain the cigarette filter capable of reducing cigarette harm. When a consumer smokes, smoke passes the internally-disposed liquid proliposome, an antioxidant and main stream smoke are in full contact since the liquid proliposome is large in surface area, gas-phase free radicals in the main stream smoke can be effectively eliminated, and strong technical support is provided for solving the problem about smoking and health.

Description

technical field [0001] The invention relates to the field of chemical technology, more specifically, to a liquid proliposome containing a composition of squalene and tea polyphenols, a preparation method thereof, and an application in reducing bases and harms of hookah-type filters. Background technique [0002] Thousands of compounds produced by smoking and the harm caused by high concentration of free radicals to the human body have attracted widespread attention. Free radicals have the strongest effect on the body and are the most harmful. They can cause lung disease, heart disease and cancer. These free radicals can cause serious damage to smokers. Smoking produces high concentrations of free radicals, including relatively long-lived solid-phase free radicals, quinones and semiquinones, polycyclic aromatic hydrocarbons free radicals, and reactive oxygen free radicals produced by their reactions with oxygen such as superoxide anion (O 2 - ), hydrogen peroxide (H 2 o 2...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A24D3/14
Inventor 江定心陈泽鹏韦建玉夏衍李文才魏彬卢少薇
Owner SOUTH CHINA AGRI UNIV
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