Preparation method for novel TiO2 nano crystal whisker materials commonly-loaded with gambogic acid

A technology of nano-whiskers and gambogic acid, which is applied in the field of preparation of nano-drug-loaded particles, can solve the problem of less development of nano-materials, achieve good photocatalytic activity, increase effective concentration, and enhance the effect of targeted and controlled release capabilities
CN103806087AInactive Publication Date: 2014-05-21THE AFFILIATED DRUM TOWER HOSPITAL MEDICAL SCHOOL OF NANJING UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE AFFILIATED DRUM TOWER HOSPITAL MEDICAL SCHOOL OF NANJING UNIV
Publication Date
2014-05-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a preparation method for novel TiO2 nano crystal whisker materials commonly-loaded with gambogic acid. The preparation method comprises the following steps: firstly, mixing hydrated titanium oxide and potassium carbonate and roasting to obtain potassium dititanate; completely exchanging K<+1> ions from the potassium dititanate by a hydrochloric acid liquid to obtain hydrated potassium dititanate; carrying out a hydrothermal reaction on the hydrated potassium dititanate and a glucose liquid; washing and drying in vacuum; and finally, roasting in the air atmosphere of 510-550 DEG C to obtain the product. With the adoption of the preparation method, nano particles with strong photocatalytic effects, small grain diameters, good water dispersibility, high encapsulation efficiency and slow release property can be obtained. A TiO2 nano crystal whisker prepared by the preparation process through adopting a chemical co-precipitation method is a novel anti-tumor preparation integrating chemotherapy, phototherapy and thermotherapy, and has a plurality of advantages of light targeting property, slow release, small side effects and the like, so that the TiO2 nano crystal whisker is the novel anti-tumor preparation which has a very good application prospect.
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Description

technical field

[0001] The invention relates to a preparation process of nano drug-loaded particles as a drug for treating cancer, specifically a new type of TiO2 co-loaded with gambogic acid 2 Nano-whisker material and preparation method thereof, and preparation of GA-TiO by using the nano-whisker material 2 Methods of nanocomposite drug delivery systems. Background technique

[0002] The main means of treating tumors are surgery, radiotherapy and chemotherapy. Although the results are quick, the side effects are very obvious. Due to the severe damage to the body's immunity caused by radiotherapy and chemotherapy, a considerable number of cancer patients cannot adhere to treatment and lose the chance of recovery. Compared with other tumor treatment methods such as biological therapy, the current traditional Chinese medicine treatment of tumors is still relatively backward. As we all know, traditional Chinese medicine is an important part of our country's treasure house o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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