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A kind of medicine for treating bronchitis, pneumonia and asthma and preparation method thereof

A technology for bronchitis and pneumonia, applied in the field of Chinese patent medicines and their preparation, can solve the problems of difficulty in formulating quality standards and quality control standards of Chinese patent medicines, unfavorable monitoring and large-scale production of Chinese patent medicines, and difficulty in clarifying the pharmacological effects of Chinese patent medicines, Achieve the effect of being conducive to quality monitoring and large-scale production, eliminating adverse reactions and reducing adverse reactions

Active Publication Date: 2017-08-04
浙江康恩贝中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Numerous medicinal materials and components make it difficult to clarify the pharmacological effects of related Chinese patent medicines. In addition, it is difficult to formulate quality standards and quality control standards for Chinese patent medicines, which is not conducive to the quality monitoring and large-scale production of Chinese patent medicines.
In addition, although the ivy extract has been clinically used in Europe for many years, it has also shown good curative effects in the treatment of bronchitis and other respiratory diseases, but at the same time, it has the problem of high adverse reaction rate

Method used

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  • A kind of medicine for treating bronchitis, pneumonia and asthma and preparation method thereof
  • A kind of medicine for treating bronchitis, pneumonia and asthma and preparation method thereof
  • A kind of medicine for treating bronchitis, pneumonia and asthma and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A preparation method of a medicine for treating bronchitis, pneumonia and asthma, comprising the following steps (see figure 1 ):

[0035] (1) Preparation of ivy volatile oil

[0036] The ivy medicinal materials (stems and leaves of ivy) are crushed, and then 10kg of crushed ivy medicinal materials and 20kg of water are added in the extraction-rectification coupling device at a mass-volume ratio of 1:2, and reflux is performed. Light brown transparent oil layer (volatile oil) and add a small amount of anhydrous sodium carbonate to it to remove a little water (control the amount of anhydrous sodium carbonate added according to the requirement of removing water) to obtain 2.8 mL of ivy volatile oil.

[0037] It should be noted that the extraction-rectification coupling device used is a device designed by the applicant, which mainly includes five parts: heating device, extraction tank, distillation tower, condenser, and oil-water separation extractor. The whole device is mainly ...

Embodiment 2

[0053] A preparation method of a medicine for treating bronchitis, pneumonia and asthma, comprising the following steps:

[0054] (1) Preparation of ivy volatile oil

[0055] The ivy medicinal materials are crushed, and then 10kg of crushed ivy medicinal materials and 30kg of water are added to the extraction-rectification coupling device at a mass-volume ratio of 1:3, and reflux is performed. The light brown transparent oil layer (volatile oil) that appears after the reflux is collected and combined Add a small amount of anhydrous sodium carbonate to remove a little water (control the amount of anhydrous sodium carbonate added according to the requirement of removing water) to prepare 2.5 mL of ivy volatile oil.

[0056] (2) Preparation of ivy saponins

[0057] The ivy medicinal materials (stems and leaves of ivy) are crushed, and then 10kg of crushed ivy medicinal materials are weighed and extracted twice with 10% ethanol solution in the extraction kettle. The mass-volume ratios of ...

Embodiment 3

[0059] A preparation method of a medicine for treating bronchitis, pneumonia and asthma, comprising the following steps:

[0060] (1) Preparation of ivy volatile oil

[0061] The ivy medicinal materials are crushed, and then 10kg of crushed ivy medicinal materials and 10kg of water are added in the extraction-rectification coupling device at a mass-volume ratio of 1:1, and reflux is performed. The light brown transparent oil layer (volatile oil) that appears after the reflux is collected and combined A small amount of anhydrous sodium carbonate was added to remove a little water, and 2.9 mL of ivy volatile oil was prepared.

[0062] (2) Preparation of ivy saponins

[0063] Crush the ivy medicinal materials (stems and leaves of ivy), then weigh 10kg of the crushed ivy medicinal materials and extract twice with 90% ethanol solution in the extraction kettle. The mass-volume ratios of the ivy medicinal materials and the ethanol solution are respectively It is 1:5 (the first reflux materi...

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Abstract

The invention provides a medicine for treating bronchitis, pneumonia and asthma and a preparation method thereof. The medicine is prepared by mixing ivy volatile oil and ivy saponin in a volume mass ratio of 1:(40-100). The preparation method comprises the following steps: (1) preparing ivy volatile oil; (2) preparing ivy saponin; (3) preparing an effective part ingredient, namely preparing the effective part ingredient from the ivy volatile oil and the ivy saponin; (4) preparing a soft capsule or an oral solution for treating bronchitis, pneumonia and asthma. The preparation method is simple, convenient and reliable, and is convenient for formulation of the Chinese patent medicine quality standard and quality control standard in production, and is advantageous to quality monitoring and large-scale production of Chinese patent medicine products; cilia, possibly causing adverse response, on ivy leaves can be removed, so that adverse response after the medicine is taken can be reduced and eliminated; animal tests prove that the prepare medicine has a positive effect on treatment of bronchitis, pneumonia and asthma.

Description

Technical field [0001] The invention belongs to the technical field of Chinese patent medicines and their preparation, and relates to the extraction and purification of effective parts of Chinese medicines, in particular to a medicine for treating bronchitis, pneumonia and asthma and a preparation method thereof. Background technique [0002] Bronchitis, pneumonia and asthma are common respiratory diseases. Their main symptoms are fever, headache, nasal congestion, runny nose, sore throat, cough and so on. Chinese medicine believes that the causes of bronchitis are exogenous feelings and internal injuries. Exogenous feelings are the six evils and external evils invading the lung system. Internal injuries are mainly caused by the dysfunction of the internal organs. Pneumonia is often caused by the evil of wind-heat or the evil of wind-cold entering the city to dissipate heat. Asthma is caused by the invasion of external pathogens, the pathogen of wind and cold, invades the muscle...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/25A61P11/06A61P11/00
CPCA61K9/0053A61K9/08A61K9/4808A61K36/25A61K47/26A61K2236/331A61K2236/51A61K2236/53
Inventor 倪力军张立国朱婷婷谢婷赵丽丽马东升颜玮韬王南南程佳佳刘建云
Owner 浙江康恩贝中药有限公司