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Batch cultural method of nematophagous fungus in laboratory

A nematode-eating fungus and a culture method technology, applied in the field of batch cultivation of strains laboratory for the biological control of animal parasitic nematode diseases, can solve the problems of not being able to meet the requirements of batch cultivation and low production of nematode-eating fungi

Inactive Publication Date: 2015-05-13
NORTHWEST UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the production of nematode fungi is small, which cannot meet the needs of mass culture

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] (1) The nematode fungus-Duddingtonia flagrans (synonymous with Arthorbotiys flagrans) strains stored in a test tube slant at 4°C were transferred to 1% bran Plate culture medium, cultured in the dark at 26°C for 6 days, and the culture with mycelia covered with the plate was used as the primary seed. Wherein, the preparation method of 1% bran plate culture medium is: take by weighing 10g fresh bran and add distilled water 1000ml, boil on low heat for 1 hour, filter with gauze, after precipitation, get the supernatant and mix after adding 2g of agar powder per 100ml, Then divide it into Erlenmeyer flasks, and sterilize under high pressure at 121°C for 20 minutes.

[0015] (2) Use a sterile scalpel to cut off 2 squares of 4 mm × 4 mm from the culture containing the first-class seeds, transfer it to a Erlenmeyer flask containing 2% bran liquid medium, and cultivate it at 26 ° C, first 80 r / Min shaking for 60 hours, then 160r / min shaking culture for 72 hours, the liquid ...

Embodiment 2

[0018] (1) Transfer the Arthorbotiys oligospora strains stored in the slant of the test tube at 4°C to 1% bran plate medium, and culture them in the dark at 25°C for 4 days, and the mycelia covered the plate. Two thirds of the later cultures were used as primary seeds.

[0019] (2) Use a sterile scalpel to cut off 3 squares of 4 mm × 4 mm from the culture containing the first-class seeds, transfer it to a Erlenmeyer flask containing 2% bran liquid medium, and cultivate it at 25 ° C, first 80 r / Min shaking for 48 hours, then 160r / min shaking culture for 72 hours, this liquid culture as the secondary seed.

[0020] (3) Pack corn grain and wheat grain compound culture medium into polyethylene plastic bags with a length of 37 cm and a width of 11 cm. One side of the plastic bag is equipped with a sterilizing filter membrane with a diameter of 5 cm to facilitate ventilation, and it is autoclaved at 121 ° C for 30 Minutes, after cooling, inoculate the secondary seeds into the abo...

Embodiment 3

[0022] (1) Transfer the strains of Pochonia chlamydosporia (Pochonia chlamydosporia) stored on the slant of the test tube at 4°C to 1% bran plate medium, culture them in the dark at 28°C for 7 days, and the mycelium grows to Two-thirds of the culture on the plate was used as primary seed.

[0023] (2) Use a sterile scalpel to cut off 3 squares of 4 mm × 4 mm from the culture containing the first-class seeds, transfer it to a Erlenmeyer flask containing 2% bran liquid medium, and cultivate it at 28 ° C, first 80 r / Min shaking for 72 hours, and then 160r / min shaking culture for 72 hours, the liquid culture was used as the secondary seed.

[0024] (3) Pack corn grains and wheat grains compound culture medium into polyethylene plastic bags with a length of 37 cm and a width of 11 cm. One side of the plastic bag is equipped with a sterilizing filter membrane with a diameter of 5 cm to facilitate ventilation, and it is autoclaved at 121 ° C. After cooling for 30 minutes, inoculat...

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Abstract

The invention relates to a batch cultural method of a nematophagous fungus in a laboratory. The cultural method comprises the following steps: (1) preparing first-class seeds; (2) preparing second-class seeds; (3) harvesting conidium and chlamydospore. According to the invention, under the condition of the laboratory, the cultural method can be used for batch production, and establishes a solid basis for producing biological control preparations for animal parasitic diseases in an industrialized manner in the future.

Description

technical field [0001] The invention relates to a laboratory batch cultivation method for bacteria used for the biological control of animal parasitic nematode diseases, in particular to a laboratory batch cultivation method for nematode fungi. Background technique [0002] Animal parasitic nematodes are a kind of serious parasitic diseases infected by livestock, which cause serious harm to animal husbandry. Drug deworming is the main control measure. With the problems of insect resistance caused by chemical anthelmintics, the threat of drug residues in animal food to human health, and the adverse effects of drug degradation products on the ecological environment, etc., are widely recognized. The new biotechnology of controlling parasitic nematode infection by using nematode fungi to control parasitic nematode infection has attracted much attention. The infection or repeated infection of parasites reduces the harm of parasites to animals, which is of great significance for ...

Claims

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Application Information

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IPC IPC(8): C12N1/14C12R1/645
CPCC12N1/14
Inventor 蔡葵蒸刘伟陈明月韩元王波波彭建伟丁嘉烽孙龙杰李禤吴佳严谢德琼杨静许强黎晓珊易林鑫赵明旺王慧魏栓李清李丹郑天惠陈春蓉王悦萦蔺国珍王康英徐春兰李亚群秦鸽鸽王冬梅张涛杰马忠仁刘翊中白振京刘艳秋方文秀蔡彬胡黔林王帆张超杨再昀王峰
Owner NORTHWEST UNIVERSITY FOR NATIONALITIES