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Oral care solution and preparation method thereof

A technology of oral care solution and traditional Chinese medicine, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, plant raw materials, etc., and can solve problems such as no clear anti-bacterial effect on oral cavity, unsuitable for modern production technology, rough preparation technology, etc. , to achieve the effect of controlling product quality, high safety, and strong pertinence

Inactive Publication Date: 2015-05-20
GUANGXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Patent CN103830645A "An Oral Liquid for Treating Halitosis" has many medicinal flavors, complex prescriptions, rough preparation process, difficult quality control, and is not suitable for modern production processes
[0006] The composition of the patent CN102000005B "oral care solution" has no clear anti-oral special bacteria effect, and does not play a role in the mechanism of halitosis hydrogen sulfide

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A kind of oral care solution, when preparing, take 2 parts of medicinal materials Perrin and 1 part of Cyperus chinensis, extract the volatile oil components of traditional Chinese medicine by steam distillation, and set aside; extract at the same time to obtain a water extraction solution, and then concentrate the water extraction solution to a relative density of 1.05 g / ml, add ethanol to make the ethanol concentration 50%, remove insoluble substances to obtain drug ethanol solution, concentrate this solution until there is no alcohol, and obtain alcohol-soluble traditional Chinese medicine for later use; take 0.5g of Chinese medicine volatile oil, add 2.0g polysorbate 80, 1.5 g mint, stir evenly to get an oily liquid; take 4.5 g of alcohol-soluble traditional Chinese medicine, add 50g xylitol, 10ml glycerin, stir evenly to get an aqueous liquid; slowly add the oily liquid into the aqueous liquid, stir while adding, and stir evenly , add water to dilute to 1000ml; the...

Embodiment 2

[0034] A kind of oral care solution, when preparing, take 10 parts of medicinal materials Perrin and 1 part of Cyperus, extract the volatile oil components of traditional Chinese medicines by steam distillation, and set aside; extract at the same time to obtain a water extraction solution, and then concentrate the water extraction solution to a relative density of 1.15 g / ml, add ethanol to make the ethanol concentration 60%, remove insoluble substances to obtain drug ethanol solution, concentrate this solution to no alcohol, and obtain alcohol-soluble traditional Chinese medicine for subsequent use; take 0.5g of Chinese medicine volatile oil, add 3g polysorbate 20, 5g polysorbate Sorbitate 60, 0.1g mint, stir well to get an oily liquid; take 9.5 g of alcohol-soluble traditional Chinese medicine, add 1g stevioside, 20ml ethanol, 10ml polyethylene glycol 400, stir well to get a watery liquid; take the oily liquid and slowly add In the water-based liquid, stir while adding, stir ...

Embodiment 3

[0036] A kind of oral care solution, when preparing, take 5 parts of medicinal materials Perrin and 1 part of Cyperus chinensis, extract the volatile oil components of traditional Chinese medicine by steam distillation, and set aside; extract at the same time to obtain a water extraction solution, and then concentrate the water extraction solution to a relative density of 1.10g / ml, add ethanol to make the ethanol concentration 70%, remove insoluble substances to obtain drug ethanol solution, concentrate this solution to no alcohol, and obtain alcohol-soluble traditional Chinese medicine for later use; take 5.0g of Chinese medicine volatile oil, add 7g of poloxamer 188, stir Take 65g of alcohol-soluble traditional Chinese medicine, add 2g mogroside, 30ml glycerin, stir well to get water-based liquid; take oily liquid and slowly add to the water-based liquid, stir while adding, stir well, add water to dilute to 1000ml Add appropriate amount of sodium tartrate and tartaric acid t...

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PUM

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Abstract

The invention discloses an oral care solution and a preparation method thereof. The oral care solution comprises the following components by weight percent: 0.002-2.0% of traditional Chinese medicine volatile oil, 0.4-8.0% of alcohol soluble traditional Chinese medicine, 0.1-5.0% of solubilizer, 1.0-10.0% of cosolvent, 0.1-15.0% of corrigent and 60.0-98.0% of water, and the pH value range is 6.0-8.5; the traditional Chinese medicine volatile oil and the alcohol soluble traditional Chinese medicine are prepared from eupatorium and elsholtzia according to a mass ratio of 1: 1 to 10:1, by using a steam distillation method. The oral care solution disclosed by the invention is applied to oral care and has curative effects of sterilizing, diminishing inflammation and removing bad breath on such oral diseases as oral odor, periodontitis, gingivitis, and the like. The oral care solution disclosed by the invention is simple in raw materials, extract in principle and strong in pertinence, a modern mature process is adopted to well control the product quality, and the oral care solution is suitable for the demand of modern production technology, is conductive to market promotion and truly brings gospel to patients.

Description

technical field [0001] The invention relates to a medicine for treating oral diseases, in particular to an oral care solution containing traditional Chinese medicine ingredients and a preparation method thereof. Background technique [0002] Halitosis, also known as halitosis or oral odor, is a common disease and frequently-occurring disease, which seriously affects the social activities and mental health of patients. [0003] Causes of bad breath: The first is because food residues ferment in the mouth to form spoilage. The second is inflammation in the mouth, such as periodontitis, gingivitis, etc. The third cause of bad breath is what people often call "stomach heat and stomach fire". [0004] At present, the treatment methods for bad breath include western medicine treatment methods such as antibiotics and hormones, traditional Chinese medicine treatment methods such as traditional Chinese medicine, acupuncture and cupping, and daily oral care methods such as mouthwash...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61P1/02A61K36/28
Inventor 刘广覃江克姚迪华静赵彥春王红强李家元蒋毅民陈振锋
Owner GUANGXI NORMAL UNIV
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