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Preparation method of pharmaceutical composition for treating acnes

A composition and drug technology, which is applied in the preparation of medicines, pharmaceutical compositions, and cosmetics, and can solve problems such as the abuse of antibiotics

Inactive Publication Date: 2015-05-27
JINAN KANGZHONG PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many anti-acne products on the market, and the abuse of antibiotics, glucocorticoids, and chemicals is very serious, and the results are worrying

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Prescription: Ephedra 1g, Pueraria 1g, Reed Rhizome 2g, Dihuanghua 2g, Licorice 1g.

[0087] Preparation method: Take ephedra, kudzu root, reed rhizome, rehmannia glutinosa, and licorice, add glucose 0.5g, peptone 2g, zinc sulfate 0.044g, iron sulfate 0.01g, sodium sulfate 0.002g, magnesium sulfate 0.7g, manganese sulfate 0.005g, phosphoric acid Potassium dihydrogen 0.001g, dipotassium hydrogen phosphate 0.001g, add water to 1000g, heat to boiling for 1 hour to sterilize, when the temperature drops to 38°C, add 10g of bifidobacterium seed solution, culture at 38°C for 72 hours, filter, heat Sterilize by boiling for 1 hour. Add 10g of Carbopol (940), 2g of polysorbate (80), 4g of sodium hydroxide, add distilled water to 1000ml, stir evenly, subpackage and sterilize to get the gel.

Embodiment 2

[0089] Take 3g of ephedra, 3g of kudzu root, 9g of Yeguanmen, 9g of Rehmannia glutinosa, 1g of licorice, 0.5g of glucose, 2g of peptone, 0.044g of zinc sulfate, 0.01g of iron sulfate, 0.002g of sodium sulfate, 0.7g of magnesium sulfate, 0.005g of manganese sulfate, Potassium dihydrogen phosphate 0.001g, dipotassium hydrogen phosphate 0.001g, add water to 1000g, heat to boiling for 1 hour to sterilize, when the temperature drops to 38°C, inoculate the seeds of Bifidobacterium, Lactobacillus acidophilus, and Lactobacillus plantarum Into the fermentation medium, the inoculation amount of each strain of bacterial seed liquid is 10g, cultivated at 38°C for 48 hours, filtered, heated to boiling and concentrated to a relative density of 1.2, dried under reduced pressure at 60°C, and pulverized to obtain a dried traditional Chinese medicine fermented product.

[0090] Take 120 g of stearic acid, 100 g of castor oil, and 100 g of liquid paraffin, put them in an evaporating dish, heat on...

Embodiment 3

[0092]Take 5g of Scutellaria baicalensis and 6g of honeysuckle, decoct twice with water, 1.5h each time, combine the two extracts, filter, add 3g of bezoar, 0.5g of glucose, 2g of peptone, 0.044g of zinc sulfate, 0.01g of iron sulfate, 0.002g of sodium sulfate g, magnesium sulfate 0.7g, manganese sulfate 0.005g, potassium dihydrogen phosphate 0.001g, dipotassium hydrogen phosphate 0.001g, add water to 1000g, heat sterilization, when the temperature drops to 37 ℃, bifidobacterium, acidophilus milk Bacillus and Lactobacillus plantarum seed solution are inserted into the fermentation medium, the inoculum amount of each strain is 10g, cultivated at 38°C for 80 hours, filtered, heated to boiling and concentrated to a relative density of 1.12, dried under reduced pressure at 60°C, and pulverized , to obtain the dried product of traditional Chinese medicine fermentation.

[0093] Take 220g of stearyl alcohol and 250g of white vantulin, melt it on a water bath, heat it to 80°C, add...

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PUM

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Abstract

The invention discloses a preparation method of a pharmaceutical composition for treating acnes. The method is characterized by comprising a step of fermenting traditional Chinese medicinal materials with bifidobacterium, lactobacillus acidophilus and lactobacillus plantarum. Cosmetics are prepared by a conventional method in pharmaceutics. An experiment proves that the curative effect can be further improved.

Description

technical field [0001] The invention relates to medicines, in particular to a preparation method of a medicine composition for treating acne, and belongs to the technical fields of medicines and cosmetics. Background technique [0002] Acne, commonly known as acne, is an inflammatory lesion that occurs in the pilosebaceous gland and its surrounding tissues. It is more common in various groups of people, especially young people. For this reason, many cosmetic companies have launched acne-removing products. The type and content of active ingredients in anti-acne products not only determine the effect of anti-acne, but also have a certain impact on the health of consumers. Antibiotics and glucocorticoids have a certain therapeutic effect on acne and are often used in external medicine. Salicylic acid has moderate anti-acne and antibacterial properties, and is less irritating to the skin, so it is also commonly used as an acne treatment. Compared with drugs, cosmetics have hi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K36/539A61K36/804A61K8/99A61K8/98A61K8/97A61P17/10A61P31/04A61K35/413
Inventor 田原方方周冉伦立军冯巧巧
Owner JINAN KANGZHONG PHARMA TECH DEV
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