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Traditional Chinese medicine composition for treating recurrent oral ulceration and preparation method thereof

A technique for oral ulcers and recurrence, which is applied in the field of traditional Chinese medicine compositions for the treatment of recurrent oral ulcers and the field of preparation thereof, can solve the problems of insignificant treatment effect and the like, and achieve the effects of remarkable effect and definite curative effect.

Inactive Publication Date: 2015-07-22
QINGDAO STOMATOLOGICAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The technical problem to be solved by the present invention is that most of the medicines for treating recurrent oral ulcers in the prior art use western medicines, which are mainly anti-inflammatory and bactericidal, and the therapeutic effect is not obvious.

Method used

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  • Traditional Chinese medicine composition for treating recurrent oral ulceration and preparation method thereof
  • Traditional Chinese medicine composition for treating recurrent oral ulceration and preparation method thereof
  • Traditional Chinese medicine composition for treating recurrent oral ulceration and preparation method thereof

Examples

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preparation example Construction

[0072] The preparation process of the oral buccal agent for external use of the present invention is as follows: 1000g of peppermint, 1000g of Qingdai, and 1000g of ebony plum are distilled and extracted by the steam method, and the extracted white crystals are crushed, passed through a fine sieve of 120-150 mesh, and set aside; Tea 1000g, black nightshade 1000g, forsythia 1000g, capillary wormwood 1000g, comfrey 1000g, isatidis root 1000g, peony cortex 1000g, bletilla striata 1000g, scutellaria baicalensis 1000g, diffusa hedyotis 1000g, add 10 times the mass of ethanol to soak 2- 3 hours, then heated and refluxed for 2 extractions, 1 to 2 hours each time, combined the 2 extracts and stood still; combined the above two extracts, recovered ethanol under reduced pressure and concentrated to a concentration of 0.6g crude drug / mL , after suction filtration, the relative density of the filtrate is about 1.06 at 20°C; reduce the pressure to 0.03-0.08MPa, keep the temperature at 60-80...

Embodiment 1

[0118] Example 1: Zhang, male, 45 years old, self-reported repeated mouth ulcers for 2 years, took oral dexamethasone, vitamins, and externally applied oral ulcer membranes, and the treatment was effective. After 1 week of drug withdrawal, mouth ulcers appeared again, and contact irritation Sexual food pain, restricted eating, poor sleep at night recently, sweating, sore waist and knees, constipation. Examination: There are multiple scattered ulcers of different sizes on the lips and buccal mucosa, the center is sunken and yellowish, the surrounding is congested in a red halo shape, the tongue is red and thin yellow, and the pulse is thready. Diagnosed as recurrent oral ulcer, card belongs to hyperactivity of fire due to deficiency of YIN. Oral basic prescription: Angelica 12g, Gentiana 12g, Imperata 13g, Astragalus 11g, Anemarrhena 13g, Cornus officinalis 12g, Polygala 12g, Atractylodes macrocephala 13g, Bupleurum 12g, Phellodendron 11g, Ligustrum lucidum 12g, Dandelion 12g, ...

Embodiment 2

[0119] Embodiment 2: Kim, female, 48 years old. Patient's oral ulceration, pharynx, tongue dryness pain, show effect repeatedly 6 years, increase the weight of in January. When visiting the doctor, the mucous membranes on both sides of the oral cavity showed diffuse ulceration, the ulcers in the tongue were in pieces, the movement was inflexible, the upper and lower lips were also ulcerated, it was difficult to open the mouth and swallow, the stool was dry, accompanied by abdominal pain, especially when it was cold, and dry mouth Bitter, red tongue, thick and greasy fur, stringy and rapid pulse. Taking vitamin B2, multivitamins and Chinese patent medicines Niuhuang Jiedu Tablets, Niuhuang Qingwei Pills, etc. were all ineffective, and the stool became drier, abdominal distension and pain, and dry mouth aggravated. This is caused by accumulation of damp and heat, stagnation of the spleen and stomach, prolonged stagnation of deficiency and cold in the middle Jiao, and inflammati...

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Abstract

The invention provides a traditional Chinese medicine composition for treating recurrent oral ulceration. An internal-use medicine comprises the following components in parts by weight: 10-20 parts of Chinese angelica, 10-20 parts of Chinese gentian, 10-20 parts of lalang grass rhizome, 10-20 parts of milkvetch root, 10-20 parts of common anemarrhena rhizome, 10-20 parts of common macrocarpium fruit, 10-20 parts of thin leaf milkwort root-bark, 10-20 parts of large head atractylodes rhizome, 10-20 parts of radix bupleuri, 10-20 parts of bark of Chinese corktree, 10-20 parts of glossy privet fruit, 10-20 parts of mongolian dandelion herb, 10-20 parts of yerbadetajo herb, 10-20 parts of codonopsis pilosula, 10-20 parts of red paeony root, 10-20 parts of spreading hedyotis herb, 10-20 parts of herb of shorthorned epimedium and 10-20 parts of common lophantherum herb. An external-use medicine comprises the following components in parts by weight: 10-20 parts of catechu, 10-20 parts of black nightshade herb, 10-20 parts of virgate wormwood herb, 10-20 parts of root of sinkiang arnebia, 10-20 parts of mint, 10-20 parts of indigowoad root, 10-20 parts of tree peony bark, 10-20 parts of common bletilla pseudobulb, 10-20 parts of baikal skullcap root, 10-20 parts of spreading hedyotis herb, 10-20 parts of dark plum fruit and 10-20 parts of natural indigo. The whole formula of the traditional Chinese medicine composition is mainly used for nourishing the liver and the kidney, and is secondary used for soothing liver-qi stagnation, purging fire and removing toxin to simultaneously perform reinforcing and reducing methods and mutually aiding yin and yang; and the medicine is taken internally and externally, systemic medicine administration and local medicine administration are combined, symptoms and signs of traditional Chinese medicine are combined, and the effect is remarkable.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating recurrent oral ulcers and a preparation method thereof. Background technique [0002] Recurrent oral ulcers, also known as oral recurrent aphthous ulcers, are clinically common and frequently occurring oral diseases. Modern medicine is not yet clear about its pathogenesis, but it is believed to be related to immune abnormalities, microcirculation disorders, digestive system diseases, and endocrine disorders. [0003] Traditional Chinese medicine believes that although the disease occurs in the mouth, it is closely related to the meridians of the viscera, because the spleen opens to the mouth, the heart opens to the tongue, the kidney veins connect to the tongue, and the cheeks and gums belong to the stomach and large intestine meridian. Injury due to factors such as diet...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P1/02
Inventor 于艳玲韩晓红唐仲良王万春
Owner QINGDAO STOMATOLOGICAL HOSPITAL