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A kind of preparation method of medical dressing

An electrospinning solution and the obtained technology are applied in the fields of medical science, rayon manufacturing, fiber chemical characteristics, etc., and can solve the problems of inconvenient observation of wound surfaces, opacity, and bacterial proliferation and easy infection.

Inactive Publication Date: 2017-07-07
NANYANG CITY CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after the adhesive layer absorbs a large amount of wound exudate, it often swells and even causes the wound to separate, and the body fluid it absorbs is not easy to evaporate, resulting in a large number of bacteria multiplying at the wound and prone to infection
Foaming polymer medical dressings have fast and powerful absorption capacity for exudate, but due to the strong absorption capacity, it may affect the self-cleaning process for low-level penetration wounds. In addition, foaming polymer medical dressings The dressing is opaque, making it difficult to observe the wound surface

Method used

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  • A kind of preparation method of medical dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A method for preparing a medical dressing includes the following steps:

[0025] Step 1. Dissolve polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with 80wt% ethanol aqueous solution to obtain the electrospinning solution initial material I, where polyvinyl acetate, methyl vinyl The weight ratio of ether-maleic anhydride copolymer and collagen is 3:2:4;

[0026] Step 2. Dissolve polymethacrylic acid, acrylamide and N,N-methylenebisacrylamide with 68wt% formic acid aqueous solution to obtain the electrospinning solution preliminary material II. Among them, polymethacrylic acid, acrylamide and N, The weight ratio of N-methylenebisacrylamide is 1:3:2;

[0027] Step 3. Mix the electrospinning solution initial material I obtained in Step 1 with the electrostatic spinning solution initial material II obtained in Step 2, add nano clay, nano silver, vitamin C, borax, ethylene glycol, and mannose, and then stir the mixture After emulsification, the electr...

Embodiment 2

[0033] A method for preparing a medical dressing includes the following steps:

[0034] Step 1. Dissolve polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with 80wt% ethanol aqueous solution to obtain the electrospinning solution initial material I, where polyvinyl acetate, methyl vinyl The weight ratio of ether-maleic anhydride copolymer and collagen is 6:4:8;

[0035] Step 2. Dissolve polymethacrylic acid, acrylamide and N,N-methylenebisacrylamide with 68wt% formic acid aqueous solution to obtain the electrospinning solution preliminary material II. Among them, polymethacrylic acid, acrylamide and N, The weight ratio of N-methylenebisacrylamide is 2:6:7;

[0036] Step 3. Mix the electrospinning solution initial material I obtained in Step 1 with the electrostatic spinning solution initial material II obtained in Step 2, add nano clay, nano silver, vitamin C, borax, ethylene glycol, and mannose, and then stir the mixture After emulsification, an electro...

Embodiment 3

[0042] A method for preparing a medical dressing includes the following steps:

[0043] Step 1. Dissolve polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen with 80wt% ethanol aqueous solution to obtain the electrospinning solution initial material I, where polyvinyl acetate, methyl vinyl The weight ratio of ether-maleic anhydride copolymer and collagen is 6:4:9;

[0044] Step 2. Dissolve polymethacrylic acid, acrylamide and N,N-methylenebisacrylamide with 68wt% formic acid aqueous solution to obtain the electrospinning solution preliminary material II. Among them, polymethacrylic acid, acrylamide and N, The weight ratio of N-methylenebisacrylamide is 4:5:7;

[0045] Step 3. Mix the electrospinning solution initial material I obtained in Step 1 with the electrostatic spinning solution initial material II obtained in Step 2, add nano clay, nano silver, vitamin C, borax, ethylene glycol, and mannose, and then stir the mixture After emulsification, an electro...

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Abstract

The invention discloses a preparation method of a medical dressing. Firstly, polyvinyl acetate, methyl vinyl ether-maleic anhydride copolymer and collagen are dissolved in an aqueous ethanol solution to obtain an electrospinning liquid primary material I, and then the polyvinyl acetate Dissolving methacrylic acid, acrylamide and N,N-methylenebisacrylamide with formic acid aqueous solution to obtain the electrospinning solution primary material II, and then mixing the electrospinning solution primary material I with the electrospinning solution primary material II, Adding nano clay, nano silver, vitamin C, borax, ethylene glycol and mannose, emulsifying after stirring, spinning the obtained electrospinning solution into a fiber film by electrospinning, vacuum filtering and drying to obtain a medical dressing. The obtained medical dressing can effectively sterilize and eliminate inflammation, improve the microcirculation of tissues around the injury, play the role of analgesia, inhibit bacterial reproduction and repair wounds, and is safe to use and has no toxic and side effects on human body.

Description

Technical field [0001] The invention belongs to the technical field of medical dressings, and specifically relates to a preparation method of medical dressings. Background technique [0002] In daily life, people will cause wounds due to trauma, burns, or surgery. In order to prevent harmful microorganisms from infecting the wound and accelerate the healing of the wound, it is usually necessary to apply a medical dressing to the wound. Medical dressing is a kind of covering to wrap wounds. It is mainly used to cover sores, wounds or other damages to protect the wound, absorb secretions, reduce infection and promote healing. [0003] Traditional medical dressings are mainly made of gauze, cotton and other materials whose main function is to clean or protect the wound. Such medical dressings can effectively protect the wound surface, have a strong ability to absorb exudate, and are low in cost, easy to obtain, and simple to make. reusable. But its shortcomings are particularly pro...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/32A61L15/24A61L15/44D01F8/10D01F8/02D01F1/10D01D5/00
Inventor 李明林马慧利
Owner NANYANG CITY CENT HOSPITAL
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