Preparation technology of disodium adenosine triphosphate capable of reducing energy consumption

Abstract

The invention discloses a preparation technology of disodium adenosine triphosphate capable of reducing energy consumption. An appropriate amount of room temperature reverse osmosis water is used for dissolving adenosine to prepare an adenosine solution, the energy consumption is saved by 15% or higher, the operation is simple, and the damage to enzymes is effectively avoided. In the prior art, magnesium sulfate is selectively used as an enzymatic reaction metal ionic compound in a biochemical reaction, but the adsorption capacity of strong basic anion resin used in a subsequent technology for sulfate ions is extremely high, a great difficulty is brought for later resin regeneration treatment, and new foreign ions can be introduced; however, when magnesium chloride is used for replacing the magnesium sulfate, the adsorption capacity of strong basic anion resin for chloride ions is weaker than that of strong basic anion resin for sulfate ions, the later resin regeneration treatment is facilitated, and new foreign ions cannot be introduced. According to the preparation technology, benzalkonium bromide is used as an active agent; the benzalkonium bromide is a nontoxic and innocuous disinfectant , and the difficulty is not increased for later treatment, so that the benzalkonium bromide is a reasonable substitute; a two-stage method is adopted for vacuum drying, so that not only is the pollution avoided, but also the time is saved.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a preparation process of energy-saving adenosine triphosphate disodium. Background technique [0002] Adenosine triphosphate disodium, chemical name: adenosine-5'-triphosphate disodium salt trihydrate, molecular formula: C 10 h 14 N 5 Na 2 o 13 P 3 ·3H 2 O, molecular weight: 605.19, is a nucleotide derivative and participates in the metabolism of fat, protein, sugar, nucleic acid and nucleotide in the body. When energy is needed for absorption, secretion, muscle contraction and biochemical synthesis reactions in the body, adenosine triphosphate is decomposed into adenosine diphosphate and phosphate groups, and energy is released at the same time. Adenosine triphosphate disodium can penetrate the blood-cerebrospinal fluid barrier, improve the stability and reconstruction ability of the membrane structure of nerve cells, and promote the regeneration of ne...

AI Technical Summary

Problems solved by technology

[0004] In the existing technology, drugs such as ATP are generally produced in accordance with the process steps recommended by the State Food Administration or Pharmacopoeia and other guidance documents. If a drug manufacturer changes the production process for a product that has already received approval, it needs to reapply for approval. Increase the cost of manpower and material resources