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Chinese and western medicinal composition and preparation method thereof

A composition, the technology of Chinese and Western medicine, applied in the field of Chinese and Western medicine composition and its preparation, can solve the problems that bacitracin zinc is difficult to achieve the effect of disease prevention and growth promotion, aggravate the non-standard degree of drug production in animal husbandry, and increase the cost of feeding, etc., to achieve Increased therapeutic effect, superior disintegration speed performance, uniform distribution effect

Active Publication Date: 2015-09-02
中芝堂药业(山东)有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the intensification of animal husbandry production and the impact of non-standard drug use in animal husbandry production, the factors affecting the growth of livestock and poultry in animal husbandry production are becoming more and more complicated. It is difficult to achieve good disease prevention and control with a single use of bacitracin zinc and growth-promoting effects, while livestock producers will inevitably put more antibiotics in the process of raising livestock and poultry in order to pursue good disease prevention and growth-promoting effects. Non-standard degree, forming a never-ending vicious circle of abuse of antibiotics

Method used

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  • Chinese and western medicinal composition and preparation method thereof
  • Chinese and western medicinal composition and preparation method thereof
  • Chinese and western medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] (1) Investigation of the curative effect of different drug combinations on paratyphoid fever in piglets

[0042] Ingredients: Roasted Licorice, Coptidis Rhizome, Dried Ginger and Bacitracin Zinc (all commercially available products).

[0043] Case: 120 cases of paratyphoid fever in piglets with natural onset in pig farms, showing intractable diarrhea, water samples of feces, yellow green, dark green, dark brown, blood necrotic tissue or cellulose flakes mixed in feces, foul smell, symptoms On and off, recurrent; laboratory-diagnosed salmonella infection.

[0044] Prepare granules according to the raw materials in Table 1, and obtain test product 1 to test product 5 respectively; under the same feeding conditions, the diseased pigs were randomly divided into test group 1, test group 2, test group 3, test group 4, test group 5 and blank group; Test 1 to Test 5 were mixed with 2% of test product 1 to test product 5 into the piglet ration, once a day, for 3 consecutive day...

Embodiment 2

[0068] Group 1: Take 10kg of dried ginger, grind it, and pass it through a No. 9 sieve to obtain fine powder of dried ginger; take 56 kg of Coptidis rhizome, crush it, and pass it through a No. 9 sieve to obtain a fine powder of Coptis chinensis; take 15 kg of roasted licorice, add 3 times the amount of water, After boiling on high heat, decoct on low heat for 1 hour, filter, and take the filtrate; add about 2.5 times the amount of water to the dregs, boil on high heat, decoct on low heat for 40 minutes, filter, and take the filtrate; add 2 times the amount of water to the dregs, and boil on high heat Boil on low heat for 20 minutes, filter, and take the filtrate; combine the filtrate obtained three times, concentrate to the same weight as Coptidis rhizome; add bacitracin zinc 0.08kg, sodium chloride 0.2kg, sodium glutamate (MSG) 0.12kg, low Substitute 2.4kg of hydroxypropyl cellulose (L-HPC), 0.05kg of sodium dodecyl sulfate (SDS), 0.12kg of sodium glycyrrhizinate and 0.03kg o...

Embodiment 3

[0082] The type, dosage and combination of auxiliary materials are important factors of the preparation, which are directly related to whether the preparation can be obtained and the quality of the preparation obtained. The most important inspection indicators are palatability and dissolution rate. In order to prepare Jiangliancao microgranules with good palatability and fast disintegration speed, the formulation of the preparation is screened in the present invention. The specific formula is shown in Table 7.

[0083] Table 7 The preferred scheme of Gingerliancao microgranule formulation

[0084]

[0085] The above formula is prepared into fine granules by the following method: take dried ginger, pulverize it, and pass it through a No. 9 sieve to obtain a fine powder of dried ginger; take Coptidis Rhizoma, pulverize it, and pass it through a No. 9 sieve to obtain a fine powder of Coptis Rhizoma; 3 times the amount of water, boil on high heat, decoct on low heat for 1 h...

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Abstract

The invention relates to the field of veterinary medicines, in particular to a Chinese and western medicinal composition and a preparation method thereof. The Chinese and western medicinal composition is mainly prepared from dried ginger, coptis, prepared liquorice root and zinc bacitracin, and comprises 6-40 parts of dried ginger, 4-60 parts of coptis, 10-60 parts of prepared liquorice root and 0.06-2 parts of zinc bacitracin by weight. The dried ginger is pungent and hot, warms middle burner, and dispels cold coagulation of spleen and stomach; the coptis is bitter and cold and used for clearing away heat and can thicken intestines and stop dysentery; the zinc bacitracin is antibacterial and can promote growth; the dried ginger is combined with the coptis so that acrid diffuses and bitter descends, warmth and coldness are combined, internal stasis of heat is cleared and accumulation of cold is eliminated to coordinate intestines and stomach; coptis is combined with zinc bacitracin so the antibacterial effect can be improved and the drug resistance of bacteria can also be prevented; the prepared liquorice root is sweet-warm and qi-benefiting, can detoxify and coordinates the drug actions of the prescription; the four medicines are combined for use to together harmonize intestines and stomach, stop dysentery and promote growth. The preparation method is simple and easy; the prepared micro granules have good palatability, the disintegration speed performance is superior and the composition is easy to digest.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to a Chinese and Western medicine composition and a preparation method thereof. Background technique [0002] As an antibiotic with growth-promoting function and anti-bacterial infection, bacitracin zinc is widely used in animal husbandry and has achieved good results. However, with the intensification of animal husbandry production and the impact of non-standard drug use in animal husbandry production, the factors affecting the growth of livestock and poultry in animal husbandry production are becoming more and more complicated. It is difficult to achieve good disease prevention and control with a single use of bacitracin zinc and growth-promoting effects, while livestock producers will inevitably put more antibiotics in the process of raising livestock and poultry in order to pursue good disease prevention and growth-promoting effects. The degree of irregularity forms an endles...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/12A61K9/16A61P3/00A61P31/04A61K36/9068A61K33/14A61K31/198
Inventor 丁晓刚房春林杨海涵
Owner 中芝堂药业(山东)有限公司
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