Hedyotis caudatifolia volatile oil extraction technology

A technology for the extraction process of flavescens, which is applied in the field of extraction process of volatile oil of cloverleaf, can solve problems such as easy destruction and volatilization of active ingredients, difficult maintenance, lack of production process reports, etc., and achieves simple and easy extraction method Effect

Inactive Publication Date: 2015-09-16
NANJING ZELANG MEDICAL TECH
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In recent years, researchers have conducted in-depth studies on the microstructure and chemical components of volatile oils of S. flavescens, but there is a lack of corresponding production process reports.
The common extraction methods of volatile oil in traditional Chinese medicine include steam distillation and supercritical CO 2 Extraction methods, etc., all have many disadvantages:

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0014] Example 1:

[0015] Take the flag leaf ear herbal medicine, crush it, and pass it through a 40-mesh sieve; add 1% cellulase (activity 30U / mg) of the raw material, spray 0.5 times the raw material with an acetic acid / sodium acetate buffer solution of pH 4.5 to reach the hand Just hold it into a dough; take the fermented raw materials, add 60% ethanol solution equivalent to 4 times the quality of the raw materials, and use continuous countercurrent ultrasonic extraction method to continuously extract for 2 hours under the conditions of 50℃ and 20KHz, filter, and filter the filtrate through petroleum Ether extraction, concentration under reduced pressure, etc., to obtain yellow volatile oil of Eriocheir sinensis with a yield of 2.3%.

Example Embodiment

[0016] Example 2:

[0017] Take the flag leaf auricularia herb material, crush it, and pass it through a 40-mesh sieve; add 3% cellulase (activity 50U / mg) of raw material quality, spray an acetic acid / sodium acetate buffer solution of pH 5.0 equal to 1 times of the raw material to reach the hand Hold it into a dough; take the fermented raw material, add 65% ethanol solution equivalent to 6 times the weight of the raw material, and use continuous countercurrent ultrasonic extraction to extract continuously for 3 hours at 55℃ and 20KHz, filter, and filter the filtrate with ether Extraction, concentration under reduced pressure, etc., to obtain yellow volatile oil of Eriocheir sinensis with a yield of 3.1%.

Example Embodiment

[0018] Example 3:

[0019] Take the flag leaf ear herb material, crush it, and pass it through a 40-mesh sieve; add 2% cellulase (activity 40U / mg) of the raw material mass, spray 0.5 times the raw material with an acetic acid / sodium acetate buffer solution of pH 5.5 to reach the hand Just hold it into a dough; take the fermented raw material, add 70% ethanol solution equivalent to 5 times the weight of the raw material, and use continuous countercurrent ultrasonic extraction method to continuously extract 3 hours under the conditions of 60℃ and 20KHz, filter, and filter the filtrate through organic Solvent extraction, concentration under reduced pressure, etc., to obtain yellow volatile oil of Eriocheir sinensis with a yield of 2.8%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a hedyotis caudatifolia volatile oil extraction technology. The technology includes the following steps that the medical material of hedyotis caudatifolia is fetched and smashed and passes a 40-mesh screen; cellulose occupying 1-3% of the mass of the raw material is added, an acetic acid/sodium acetate buffer solution which is 0.5-1.5 times of the raw material is sprayed until the solution is clustered when being held by hand, and the pH of the buffer solution is 4.5-5.5; and extraction is carried out for 1-3 h through a continuous reflux ultrasonic extraction method, and hedyotis caudatifolia volatile oil is obtained. The extraction method is simple and easy to use, only little organic solvent is needed, and the technology is safe, non-toxic and suitable for industrial production.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a process for extracting the volatile oil of C. saponifera. Background technique [0002] Sword leaf ear grass is a shrub-like herb with upright branches of Rubiaceae Auricularia, also known as juvenile red, millennium tea, and iron broom. It is flat in nature, bitter in taste, and pungent. It is used to treat bronchial asthma, bronchitis, tuberculosis, hemoptysis, malnutrition in children, bruises, surgical bleeding, fever in children, sore throat, diarrhea, etc. Among the volatile constituents of P. saponifera, the main ones are aliphatic derivatives, terpenoid derivatives and aromatic derivatives. Terpenoids have various biological activities and are the main active ingredients of some traditional Chinese medicines. [0003] In recent years, researchers have carried out in-depth studies on the microstructure and chemical components of volatile oils of...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/748
Inventor 刘东锋杨成东
Owner NANJING ZELANG MEDICAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap