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Hydrogel emergency tobacco control patch formula and method for preparing tobacco control patch

A hydrogel and formula technology, applied in the field of hydrogel emergency tobacco control patch and preparation thereof, can solve the problem of low nicotine dosage and the like, and achieve the effects of relieving smoking symptoms, simple production process and less irritation

Inactive Publication Date: 2015-09-30
云南拓宝科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the problems existing in the existing smoking cessation and tobacco control patches, the purpose of the present invention is to provide a nicotine dosage that is low, prescribed for a short duration of use, has a good uniform and sustained release effect, is safe and controllable, has strong skin affinity, and has good adhesion properties. Composition for making hydrogel emergency tobacco control patch and method for preparing tobacco patch, which is convenient to carry and use, low in production cost, does not cause secondary environmental pollution, and has the function of alleviating and controlling smoking addiction

Method used

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  • Hydrogel emergency tobacco control patch formula and method for preparing tobacco control patch
  • Hydrogel emergency tobacco control patch formula and method for preparing tobacco control patch

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Weigh various raw materials to form the prescription of the hydrogel emergency tobacco control patch: 0.15g of natural tobacco extract, 1.1g of nicotine inclusion complex, 1.0g of peppermint extract, 6.5g of sodium polyacrylate, 1.0g of sodium carboxymethylcellulose g, 0.15 g of aluminum glycolate, 0.2 g of tartaric acid, 4.9 g of ethanol, 25 g of glycerin, and 60.0 g of purified water.

[0018] 1) Pour the weighed sodium polyacrylate, nicotine inclusion compound and aluminum glycylate into the mixing container of a vacuum mixer, add glycerin, stir it into a viscous paste liquid, then add natural tobacco extract, mint The extract and ethanol are stirred evenly to make a compound oil phase drug, which is set aside;

[0019] 2) Weigh 1.0g of sodium carboxymethyl cellulose and 0.2g of tartaric acid into the mixing drum, add 60.0g of purified water, stir evenly, and make a water phase material; glue preparation:

[0020] 3) Add the water phase material to the compounded oi...

Embodiment 2

[0023] Weigh 5g of sodium polyacrylate, 15g of nicotine clathrate and 2.0g of aluminum glycylate and pour it into a vacuum mixer stirring container, add 21.0g of glycerin, stir it into a viscous pasty liquid, and then add 0.1g of natural tobacco extract g, 3.0g of peppermint extract and 7.5g of ethanol, stir evenly to make a compound oil phase drug, and set aside; weigh 0.5g of sodium carboxymethylcellulose and 0.9g of tartaric acid and pour them into the mixing drum, add 45.0g of purified water , Stir evenly to make water-phase materials; Glue compounding: add water-phase materials to the oil-phase drug compounded in a vacuum mixer, and stir evenly for 25 minutes at a speed of 130 rpm; Coating: use hydrogel coating After finishing the coating, lamination, and curing of the adhesive stickers, they are cut by a punching and cutting machine, and then packaged to obtain the finished product. The tobacco control stickers are made into round stickers with a diameter of 3 cm, a total...

Embodiment 3

[0025] Weigh 5.0g of sodium polyacrylate, 5.0g of nicotine clathrate and 0.2g of aluminum glycylate into a vacuum mixer mixing container, add 23.0g of glycerin, stir it into a viscous paste liquid, add natural tobacco in turn to extract Stir 1.0g of mint extract, 1.6g of peppermint extract and 4.0g of ethanol to make a compound oil-phase drug for later use; weigh 2.0g of sodium carboxymethyl cellulose and 0.2g of tartaric acid and pour it into a mixing drum, add purified water 58.0g, stir evenly to make water-phase materials; glue compounding: add water-phase materials to the compounded oil-phase drug in a vacuum mixer, and stir evenly for 15 minutes at a speed of 110 rpm; coating: use hydrogel The coating machine completes the coating, lamination, and curing of the adhesive stickers. After being cut by a punching and cutting machine, the finished product is packaged. The specifications of the tobacco control stickers are made into circular stickers with a diameter of 3 cm, a t...

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Abstract

The invention discloses a hydrogel emergency tobacco control patch formula and a method for preparing a tobacco control patch. The method for preparing the tobacco control patch comprises the steps that hydrogel is prepared by mixing 0.1%-2.0% of natural tobacco extracts, 1%-15% of nicotine clathrate compound, 0.5%-3.0% of mint extracts, 5.0%-10.0% of sodium polyacrylate, 0.5%-3.0% of sodium carboxymethylcellulose, 0.1%-2.0% of dihydroxyaluminium aminoacetate, 0.2%-1.0% of dihydroxysuccinic acid, 4.0%-8.0% of ethyl alcohol, 20.0%-30.0% of glycerinum and 45.0%-60.0% of purified water, and then the hydrogel is smeared on base cloth. The tobacco control patch prepared through the method is low in nicotine content, long in stipulated use time, good in even slow-release effect, safe, controllable, high in skin friendliness, good in adhering performance and convenient to carry and use, the preparation technique is simple, secondary pollution to the environment is avoided, and the tobacco addiction can be released and controlled.

Description

technical field [0001] The invention belongs to the technical field of transdermal absorption patches, and in particular relates to a hydrogel emergency smoking control patch for relieving smoking addiction in a short period of time and a preparation method thereof. Background technique [0002] As we all know, the main hazards in cigarettes come from the six types of harmful substances released during the combustion process, including: aldehydes, nicotine, olefins, cyanide, benzopyrene, etc., among which nicotine is a The alkaloids in a variety of Solanaceae plants (Solanum) are also important components of tobacco, which are the main factors that make cigarettes addictive or dependent; at the same time, the second-hand smoke produced by burning cigarettes includes more than 40 carcinogens If it is inhaled by a non-smoker, it may also be mixed with the decay products of radon, causing great harm to human health; on February 27, 2005, the world's first convention aimed at re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K9/06A61K47/38A61P25/34A61K31/465
Inventor 刘维涓郭婷婷李鲜红熊伟左立玮
Owner 云南拓宝科技有限公司
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