Asymmetric anionic copolymerization method of methacrylate chiral polymer

Abstract

The invention provides an asymmetric anionic copolymerization method of a methacrylate chiral polymer. The method comprises the following steps: reacting methacrylic acid with trityl chloride to generate a large-volume triphenylmethyl acrylate monomer, carrying out an asymmetric anionic copolymerization reaction on the large-volume triphenylmethyl acrylate monomer and a self-made chiral function monomer under specific anion conditions to obtain a large-volume methacrylate chiral polymer; and purifying the polymer to finally obtain a target product. The structural characterization and analysis of the obtained polymer are carried out by using nuclear magnetic resonance hydrogen spectrum (<1>H-NMR) and an element analysis technology to determine that the molecular structure of the polymer and proportions of all components of the polymer accord with design requirements. Performances of the synthesized copolymer are deeply analyzed through using a gel permeation chromatograph and a polarimeter to obtain the molecular weight of the novel chiral copolymer and the distribution thereof, and the optical active characteristics of the copolymer. The method has the advantages of clear and feasible synthesis route, manure process, simple operation, easy realization, and large-scale batch production.

Description

technical field [0001] The invention relates to a synthesis method of a functional polymer material, in particular to an asymmetric anion copolymerization method of a methacrylate chiral polymer. Background technique [0002] Due to the great potential in the fields of formation mechanism, stereoregularity, and asymmetric functionalization, the asymmetric synthesis of optically active polymers has become a research hotspot that polymer scientists have paid much attention to in recent years. Some unique bulky monomers, such as trityl methacrylate (TrMA) and its homologues, can not only form highly isotactic polymers through the initiation of butyllithium in anionic polymerization systems, but also can be synthesized by All kinds of chiral anionic initiators directly form optically active polymers in asymmetric synthesis systems. The chirality of the formed polytrityl methacrylate mainly comes from its stable one-handed helical conformation, and the helical conformation forme...

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Problems solved by technology

[0003] The above researches explored the bulky methacrylate monomers and their polymerization process through the homopolymerization method, but there were relatively few studies on the copolymerization system of such bulky monomers and other functional monomers (J Am Chem Soc, 1995,117,5377; Proc Natl Acad Sci USA,2004,101,5461), and the research on the copolymerization behavior of chiral functional monomers and bulky methacrylates, and the composition and structure of such copolymers are important for their two The effects of order structure, stereoregularity and optical activity have not been reported so far.

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