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Magnetically therapeutic antibacterial haemostatic wound dressing and preparation method thereof

A hemostatic dressing, magnetic therapy technology, applied in magnetic therapy, electrotherapy, treatment and other directions, can solve problems such as affecting physical health, limited drug absorption, reducing drug effect, etc., to reduce skin deformity and hyperplasia, increase blood circulation, improve effect of treatment

Active Publication Date: 2015-12-23
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with traditional dressings, single-functional dressings have certain functions such as hemostasis, antibacterial, and wound healing, but the effect is effective
Although the effect of the drug is relatively significant, the drug is likely to cause side effects and affect the health of the body, and the absorption of the drug on the surface of the skin is limited, which greatly reduces the effect of the drug
Adding substances with magnetic therapy function to functional dressings, combining the physical curative effect with the curative effect of biological dressings to treat wounds, stop bleeding and relieve pain, promote wound healing, inhibit scars, and antibacterial research has not been reported so far.

Method used

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  • Magnetically therapeutic antibacterial haemostatic wound dressing and preparation method thereof
  • Magnetically therapeutic antibacterial haemostatic wound dressing and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0032] A magnetic therapy antibacterial and hemostatic dressing, which consists of the following components in parts by weight: 0.5 part of alginate, 0.5 part of chitosan, 0.5 part of crosslinking agent, 0.1 part of permanent magnet nanoparticles, 0.5 part of nano silicon dioxide, Growth factor 0.005 parts. The alginate is sodium alginate, the cross-linking agent is calcium chloride, the deacetylation degree of the chitosan is greater than 95%, and the molecular mass is 10000~20000Da; the permanent magnet magnetic nanoparticles It is a neodymium-iron-stilbene magnet particle, and the magnetic field strength is 0.15-0.35 tesla; the pore size of the nano-silicon dioxide is 20-80 μm; the growth factor is fibroblast growth factor or epidermal growth factor.

[0033] A preparation method of a magnetic therapy antibacterial hemostatic dressing, comprising the steps of:

[0034] S1. Dissolve alginate in purified water, mix and stir for 0.5h~1h until uniform, and prepare solution A; ...

Embodiment 2

[0041]A magnetic therapy antibacterial hemostatic dressing and a preparation method thereof, which consist of the following components in parts by weight: 2 parts of alginate, 3 parts of chitosan, 2 parts of crosslinking agent, 1 part of permanent magnet nanoparticles, and nanometer dioxide Silicon 2 parts, growth factor 0.2 parts. The alginate is sodium alginate, the cross-linking agent is calcium chloride, the deacetylation degree of the chitosan is greater than 95%, and the molecular mass is 10000~20000Da; the permanent magnet magnetic nanoparticles It is a neodymium-iron-stilbene magnet particle, and the magnetic field strength is 0.15-0.35 tesla; the pore size of the nano-silicon dioxide is 20-80 μm; the growth factor is fibroblast growth factor or epidermal growth factor.

[0042] A preparation method of a magnetic therapy antibacterial hemostatic dressing, comprising the steps of:

[0043] S1. Dissolve alginate in purified water, mix and stir for 0.5h~1h until uniform,...

Embodiment 3

[0050] A magnetic therapy antibacterial hemostatic dressing and a preparation method thereof, which consist of the following components in parts by weight: 4 parts of alginate, 6 parts of chitosan, 4 parts of crosslinking agent, 2 parts of permanent magnet nanoparticles, nanometer dioxide Silicon 4 parts, growth factor 0.5 parts. The alginate is sodium alginate, the cross-linking agent is calcium chloride, the deacetylation degree of the chitosan is greater than 95%, and the molecular mass is 10000~20000Da; the permanent magnet magnetic nanoparticles It is a neodymium-iron-stilbene magnet particle, and the magnetic field strength is 0.15-0.35 tesla; the pore size of the nano-silicon dioxide is 20-80 μm; the growth factor is fibroblast growth factor or epidermal growth factor.

[0051] A preparation method of a magnetic therapy antibacterial hemostatic dressing, comprising the steps of:

[0052] S1. Dissolve alginate in purified water, mix and stir for 0.5h~1h until uniform, a...

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Abstract

The invention belongs to the field of medicinal dressings, and particularly relates to a magnetically therapeutic antibacterial haemostatic wound dressing and a preparation method thereof. The magnetically therapeutic antibacterial haemostatic wound dressing is prepared from the following components in parts by weight: 0.5-4 parts of alginate, 0.5-6 parts of chitosan, 0.5-4 parts of a crosslinking agent, 0.1-2 parts of permanent magnetic nano-particles, 0.5-4 parts of nano-silicon dioxide and 0.005-0.5 part of growth factors. The magnetically therapeutic antibacterial haemostatic wound dressing can be used for quickly stopping bleeding, inhibiting bacteria, diminishing inflammation and promoting healing of a wound, is simple in preparation process, and is good in stability and convenient to carry.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a magnetic therapy antibacterial hemostatic dressing and a preparation method thereof. Background technique [0002] The skin can store electric charges or maintain a polarized state for a long time. The magnetic field acts on the human body tissue to affect the current distribution of the human body, the movement of charged particles, the permeability of the membrane system and the magnetic moment orientation of biological and other molecules, so that the physiological state of tissue cells , Changes in biochemical processes, causing skin vasodilation and increased blood circulation, play a role in promoting blood circulation, reducing swelling and pain, and promoting wound healing. At present, electrostatic or magnetic therapy is mostly used to treat symptoms such as bone injuries and joints, and is rarely used for clinical wound care. [0003] Chitosan and alginate are natura...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61N2/08
Inventor 卢亢陈锦涛李婷何立彬
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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