Magnetically therapeutic antibacterial haemostatic wound dressing and preparation method thereof

A hemostatic dressing, magnetic therapy technology, applied in magnetic therapy, electrotherapy, treatment and other directions, can solve problems such as affecting physical health, limited drug absorption, reducing drug effect, etc., to reduce skin deformity and hyperplasia, increase blood circulation, improve effect of treatment

Active Publication Date: 2015-12-23
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with traditional dressings, single-functional dressings have certain functions such as hemostasis, antibacterial, and wound healing, but the effect is effective
Although the effect of the drug is relatively significant, the drug is likely to cause side effects and affect the health of the body, and the absorption of the drug on the surface of the skin

Method used

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  • Magnetically therapeutic antibacterial haemostatic wound dressing and preparation method thereof
  • Magnetically therapeutic antibacterial haemostatic wound dressing and preparation method thereof

Examples

Experimental program
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Example Embodiment

[0031] Example 1

[0032] A magnetic antibacterial hemostatic dressing composed of the following components in parts by weight: 0.5 parts of alginate, 0.5 parts of chitosan, 0.5 parts of crosslinking agent, 0.1 parts of permanent magnet nanoparticles, 0.5 parts of nano-silica, 0.005 parts of growth factor. The alginate is sodium alginate, the crosslinking agent is calcium chloride, the degree of deacetylation of the chitosan is greater than 95%, and the molecular mass is 10,000 to 20,000 Da; the permanent magnet magnetic nanoparticles They are neodymium iron magnetite particles with a magnetic field strength of 0.15-0.35 Tesla; the nano-silica has a pore size of 20-80 μm; and the growth factor is fibroblast growth factor or epidermal cell growth factor.

[0033] A preparation method of a magnetic therapy antibacterial hemostatic dressing includes the following steps:

[0034] S1. Dissolve alginate in purified water, mix and stir for 0.5h~1h to uniformity to prepare solution A; diss...

Example Embodiment

[0040] Example 2

[0041] A magnetic antibacterial hemostatic dressing and a preparation method thereof, which are composed of the following components in parts by weight: 2 parts of alginate, 3 parts of chitosan, 2 parts of crosslinking agent, 1 part of permanent magnet nanoparticles, and nano-dioxide 2 parts of silicon and 0.2 parts of growth factor. The alginate is sodium alginate, the crosslinking agent is calcium chloride, the degree of deacetylation of the chitosan is greater than 95%, and the molecular mass is 10,000 to 20,000 Da; the permanent magnet magnetic nanoparticles They are neodymium iron magnetite particles with a magnetic field strength of 0.15-0.35 Tesla; the nano-silica has a pore size of 20-80 μm; and the growth factor is fibroblast growth factor or epidermal cell growth factor.

[0042] A preparation method of a magnetic therapy antibacterial hemostatic dressing includes the following steps:

[0043] S1. Dissolve alginate in purified water, mix and stir for 0...

Example Embodiment

[0049] Example 3

[0050] A magnetic therapy antibacterial hemostatic dressing and a preparation method thereof, which are composed of the following components in parts by weight: 4 parts of alginate, 6 parts of chitosan, 4 parts of crosslinking agent, 2 parts of permanent magnet nanoparticles, and nano-dioxide Silicon 4 parts, growth factor 0.5 parts. The alginate is sodium alginate, the crosslinking agent is calcium chloride, the degree of deacetylation of the chitosan is greater than 95%, and the molecular mass is 10,000 to 20,000 Da; the permanent magnet magnetic nanoparticles They are neodymium iron magnetite particles with a magnetic field strength of 0.15-0.35 Tesla; the nano-silica has a pore size of 20-80 μm; and the growth factor is fibroblast growth factor or epidermal cell growth factor.

[0051] A preparation method of a magnetic therapy antibacterial hemostatic dressing includes the following steps:

[0052] S1. Dissolve alginate in purified water, mix and stir for 0...

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Abstract

The invention belongs to the field of medicinal dressings, and particularly relates to a magnetically therapeutic antibacterial haemostatic wound dressing and a preparation method thereof. The magnetically therapeutic antibacterial haemostatic wound dressing is prepared from the following components in parts by weight: 0.5-4 parts of alginate, 0.5-6 parts of chitosan, 0.5-4 parts of a crosslinking agent, 0.1-2 parts of permanent magnetic nano-particles, 0.5-4 parts of nano-silicon dioxide and 0.005-0.5 part of growth factors. The magnetically therapeutic antibacterial haemostatic wound dressing can be used for quickly stopping bleeding, inhibiting bacteria, diminishing inflammation and promoting healing of a wound, is simple in preparation process, and is good in stability and convenient to carry.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a magnetic therapy antibacterial hemostatic dressing and a preparation method thereof. Background technique [0002] The skin can store electric charges or maintain a polarized state for a long time. The magnetic field acts on the human body tissue to affect the current distribution of the human body, the movement of charged particles, the permeability of the membrane system and the magnetic moment orientation of biological and other molecules, so that the physiological state of tissue cells , Changes in biochemical processes, causing skin vasodilation and increased blood circulation, play a role in promoting blood circulation, reducing swelling and pain, and promoting wound healing. At present, electrostatic or magnetic therapy is mostly used to treat symptoms such as bone injuries and joints, and is rarely used for clinical wound care. [0003] Chitosan and alginate are natura...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61N2/08
Inventor 卢亢陈锦涛李婷何立彬
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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