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Application of alkali modified molecular sieve serving as catalyst in reaction for conjugation preparation of conjugated linoleic acid though coin oil

A conjugated linoleic acid and molecular sieve technology, which is used in molecular sieve catalysts, physical/chemical process catalysts, preparation of organic compounds, etc., to achieve the effects of high conjugated conversion rate, easy availability of raw materials and less dosage

Active Publication Date: 2015-12-30
ZHONGKAI UNIV OF AGRI & ENG +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor found through experiments that the linoleic acid in corn oil can be converted into conjugated linoleic acid by using alkali-modified molecular sieve as a catalyst, while unmodified molecular sieve has no such catalytic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] The preparation method of alkali-modified molecular sieve of the present invention comprises the following steps:

[0022] 1) Add ethyl orthosilicate to water, stir and heat up to 50-60°C, then add dodecylamine and anhydrous sodium metaaluminate, and stir evenly;

[0023] 2) Add 0.5-1.0mol / L alkali solution dropwise until the pH of the solution is 10-11, and continue to stir for 2-3 hours;

[0024] 3) Transfer the solution in step 2) into a high-pressure hydrothermal reaction kettle, remove oxygen, fill in hydrogen until the pressure in the kettle is 0.8-2.0MPa, then raise the temperature to 110-160°C, react for 40-60 hours, and terminate the reaction ;

[0025] 4) Suction filtration, washing the obtained solid with water until neutral, drying at 80-100° C. for 8-10 hours, grinding the solid and heat-treating at 450-650° C. for 5-7 hours to obtain an alkali-modified molecular sieve.

[0026] Preferably, the mass ratio of ethyl orthosilicate, water, dodecylamine, and a...

Embodiment 1

[0037] 1) Preparation of alkali-modified molecular sieves:

[0038] Add 20g of tetraethyl orthosilicate to 200mL of deionized water, stir at a constant temperature of 55°C, then add 2g of dodecylamine and 0.1g of anhydrous sodium metaaluminate, and then add dropwise 0.5mol / L NaOH solution to adjust the pH value to 10~ 11. After continuing to stir for 2 hours, transfer the solution into a polytetrafluoroethylene-lined high-pressure reactor, replace the oxygen in the reactor with nitrogen after sealing, then fill in hydrogen until the pressure in the reactor is 1.5MPa, and then raise the temperature to 160 °C, react for 40 hours. After the reaction, the material was taken out by depressurization and suction filtered, the solid was washed with deionized water until it became neutral, and then dried at 100°C for 8 hours. After the solid was ground, it was heat-treated at 550°C for 6 hours to obtain an alkali-modified molecular sieve. After measurement, the specific surface (BET...

Embodiment 2

[0042] 1) Preparation of alkali-modified molecular sieves:

[0043] Add 20g of tetraethyl orthosilicate to 250mL of deionized water, stir at a constant temperature of 50°C, then add 3g of dodecylamine and 0.15g of anhydrous sodium metaaluminate, and then add dropwise 0.7mol / L NaOH solution to adjust the pH value to 10~ 11. After continuing to stir for 2.5 hours, transfer the solution into a polytetrafluoroethylene-lined high-pressure reactor, replace the oxygen in the reactor with nitrogen after sealing, and then fill in hydrogen until the pressure in the reactor is 0.8MPa, and then raise the temperature to 130 °C, react for 48 hours. After the reaction, the material was taken out by depressurization and suction filtered, the solid was washed with deionized water to neutrality and then dried at 90°C for 9 hours, the solid was ground and then heat-treated at 450°C for 7 hours to obtain an alkali-modified molecular sieve. After determination, the specific surface (BET) of mol...

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Abstract

The invention discloses application of an alkali modified molecular sieve serving as a catalyst in a reaction for conjugation preparation of conjugated linoleic acid though coin oil. The process of using the alkali modified molecular sieve to catalyze the corn oil for conjugation preparation of the conjugated linoleic acid comprises the following steps that the corn oil, the alkali modified molecular sieve and a solvent are added into a high-pressure reaction kettle, oxygen is removed, protection gas is introduced, stirring is conducted till the temperature is raised to 180-220 DEG C, an reaction is conducted for 3-5 hours and then ended, the catalyst and the solvent are removed, and the conjugated linoleic acid is obtained. The molecular sieve is modified by adding alkali in the preparing process, the conjugation catalytic activity of the molecular sieve on the corn oil is achieved, and the pore diameter of the molecular sieve is effectively regulated by regulating the hydrogen pressure in the hydrothermal reaction process. Raw materials of the molecular sieve are easy to obtain, the preparing method is simple, and the catalyzing efficiency is high. When the molecular sieve serves as the catalyst for conjugation preparation of the conjugated linoleic acid reaction through the coin oil, the using amount is small, the conjugation conversion rate is high, products can be easily separated, and the technological process are environmentally friendly.

Description

technical field [0001] The invention relates to the application of an alkali-modified molecular sieve as a reaction catalyst for preparing conjugated linoleic acid by conjugating corn oil. Background technique [0002] Conjugated Linoleic Acid (CLA) is a class of octadecadienoic acid containing cis or trans conjugated double bonds at the 9 and 11, 10 and 12 or 11 and 13 carbon atoms. A mixture of fatty acid isomers different from the unsaturated double bond position and spatial configuration of linoleic acid. [0003] Conjugated linoleic acid has anti-tumor, anti-oxidation, lower animal and human cholesterol, triglyceride and low-density lipoprotein, increase muscle, resist atherosclerosis, improve immunity, increase bone density, inhibit obesity, prevent and treat diabetes, etc. It has a variety of important physiological functions and has broad application prospects in the fields of medicine, health products, food and feed. [0004] However, in nature, the content of con...

Claims

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Application Information

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IPC IPC(8): B01J29/00B01J35/10C07C57/12C07C51/353
Inventor 刘其海王荣辉贾振宇周新华胡文斌
Owner ZHONGKAI UNIV OF AGRI & ENG