Perilla oil oral emulsion with lipid-lowering nutritious function and preparation method thereof

A technology of perilla seed oil oral emulsion and nutritional effect, which is applied in the field of preparation of perilla seed oil oral emulsion, can solve the problems of perilla seed oil soft capsules, such as high price, discomfort for patients with ulcers, greasy taste, etc., to achieve convenience Large-scale production, good thermodynamic stability, good absorption effect

Inactive Publication Date: 2016-02-03
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, perilla seed oil products circulating in the market are mainly perilla seed oil and perilla seed oil soft capsules, among which perilla seed oil is inconve...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take 2ml of perilla seed oil, 800.6g of Tween, and 0.5g of glyceryl monostearate, mix and disperse evenly as the oil phase; add 3ml of water, use high shear to help emulsify, repeat 3 times, each time for 3 minutes to obtain colostrum , add the remaining 4ml of water, mix with colostrum evenly, transfer to a high-pressure homogenizer and homogenize for 5-10 times under 50-90MPa pressure, filter and fill, sterilize in a rotating water bath at 115°C-121°C for 30min, 4- Refrigerate at 20°C away from light. The measured content of α-linolenic acid is: 2.5%-30%.

[0018] Centrifugal stability test of the emulsion: Put the oral emulsion of perilla seed oil in a 10ml centrifuge tube, centrifuge at 4000r / min for 30min, take it out for observation, no stratification is found, which proves that the stability is good.

[0019] Thermal stability test of the emulsion: put the perilla seed oil oral emulsion in a test tube, seal it, put it in a constant temperature water bath at 37°C...

Embodiment 2

[0021] Take 2ml of perilla seed oil, 800.6g of Tween, and 0.5g of glyceryl monostearate, mix and disperse evenly as the oil phase; take 0.001g of sodium saccharin and dissolve it in 3ml of water, mix it with the oil phase, and use high shear to help Emulsification, repeated 3 times, each time for 3 minutes to obtain colostrum, add the remaining 4ml of water, mix with colostrum evenly, transfer to a high-pressure homogenizer for 5-10 times under 50-90MPa pressure, filter and pot, 115 Sterilize in a rotating water bath at ℃-121℃ for 30min, and refrigerate at 4-20℃ in the dark.

Embodiment 3

[0023] Take 2ml of perilla seed oil, 800.6g of Tween, and 0.5g of glyceryl monostearate, mix and disperse evenly as the oil phase; dissolve 0.001g of sodium saccharin and 0.02g of citric acid in 3ml of water, and mix well with the oil phase. Use high shear to help emulsify, repeat 3 times, each time for 3 minutes to get colostrum, add the remaining 4ml of water, mix with colostrum evenly, transfer to a high-pressure homogenizer for 5-10 times under 50-90MPa pressure, filter After filling and sealing, sterilize in a rotating water bath at 115°C-121°C for 30 minutes, and refrigerate at 4-20°C in the dark.

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PUM

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Abstract

The invention discloses a perilla oil oral emulsion with a lipid-lowering nutritious function, and a preparation method thereof. The invention discloses an oil-in-water type perilla oil oral emulsion and the preparation method thereof. The emulsion takes perilla oil as a main raw material, and is characterized by being prepared through the following components according to proportion: 5 to 50 percent of the perilla oil, 0.5 to 30 percent of an emulgator, 0 to 0.5 percent of a corrigent and the balance of purified water, and emulsification is adopted as the preparation method. Based on the perilla oil, the perilla oil oral emulsion has a delicate flavor and also has an anti-oxidation effect, and an antioxidant and a smell mask are not required to add. Compared with a conventional product, the emulsion provided by the invention is high in perilla oil content, good in taste and convenient to eat, is wide in applicable human populations, and can obtain a better effect under low dosage; the emulsion is relatively good in dispersibility and thermodynamic stability, has low probability of phase splitting and precipitating, is easy to store, simple in process, convenient for large scale production, and has great social value and economic value.

Description

technical field [0001] The invention relates to a preparation method of perilla seed oil oral emulsion which has lipid-lowering nutrition and can assist in lowering blood fat and blood pressure. Background technique [0002] α-linolenic acid is an essential fatty acid for the human body. It undergoes a series of metabolism in the human body to produce two substances that are important to the human body, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Memory, improving cardiovascular and cerebrovascular functions, and delaying the aging of the body all have significant effects. Perilla seed oil contains 50% to 70% α-linolenic acid, which means that daily intake of 3-5g perilla seed oil can meet the amount of α-linolenic acid required by the human body. Since α-linolenic acid has fewer double bonds than EPA and DHA, perilla seed oil has stronger oxidation stability than fish oil, and perilla seed oil does not contain cholesterol contained in fish oil, and has high...

Claims

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Application Information

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IPC IPC(8): A61K36/535A61K9/107A23L33/10A61P9/12A61P3/06
CPCY02A40/90
Inventor 易醒肖小年孟培侯海涛刘唤桂静芬
Owner NANCHANG UNIV
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