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Bacterial cellulose compound cuprous oxide antimicrobial dressing and preparation method thereof

A technology of bacterial cellulose and cuprous oxide, applied in medical science, bandages, absorbent pads, etc., can solve problems such as limited application, and achieve the effects of excellent antibacterial properties, simple and controllable preparation method, and high water content

Active Publication Date: 2016-02-10
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore limit the application of this patent method aspect antibacterial dressing

Method used

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  • Bacterial cellulose compound cuprous oxide antimicrobial dressing and preparation method thereof
  • Bacterial cellulose compound cuprous oxide antimicrobial dressing and preparation method thereof
  • Bacterial cellulose compound cuprous oxide antimicrobial dressing and preparation method thereof

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Embodiment 1

[0034] A preparation method of bacterial cellulose composite cuprous oxide antibacterial dressing, firstly, a bacterial cellulose hydrogel film is prepared, and the bacterial cellulose hydrogel film is used as a base material, which is obtained after the pure bacterial cellulose hydrogel film is processed ; The pure bacterial cellulose hydrogel film is produced by the secretion of Acetobacter xylinum, and the bacteria protein and the residual medium adhered to the cellulose film are separated and purified to reach the bacterial dressing grade of bacterial cellulose. The mass percentage of pure bacterial cellulose hydrogel film is 1%. Separation and purification refers to that the secreted bacterial cellulose hydrogel film is soaked in 5% NaOH aqueous solution at a temperature of 80°C. Heat for 3 hours, and then rinse repeatedly with double distilled water until neutral. The grade of medicinal dressings refers to the hygienic standard GB15980-1995 for disposable medical supplies...

Embodiment 2

[0041] A preparation method of bacterial cellulose composite cuprous oxide antibacterial dressing, firstly, a bacterial cellulose hydrogel film is prepared, and the bacterial cellulose hydrogel film is used as a base material, which is obtained after the pure bacterial cellulose hydrogel film is processed ; The pure bacterial cellulose hydrogel film is secreted by Acetobacter acetogenes, after separation and purification to remove bacterial protein and residual culture medium adhering to the cellulose film, the bacterial cellulose reaches the grade of medicinal dressings, and the bacterial cellulose accounts for The mass percentage of pure bacterial cellulose hydrogel film is 5%. Separation and purification refers to that the secreted bacterial cellulose hydrogel film is soaked in a 5% NaOH aqueous solution at a temperature of 100°C. Heat for 4 hours, then rinse repeatedly with double distilled water until neutral. The grade of medicinal dressings refers to the hygienic standar...

Embodiment 3

[0046] A preparation method of bacterial cellulose composite cuprous oxide antibacterial dressing, firstly, a bacterial cellulose hydrogel film is prepared, and the bacterial cellulose hydrogel film is used as a base material, which is obtained after the pure bacterial cellulose hydrogel film is processed The pure bacterial cellulose hydrogel film is secreted by Acetobacter acetibacterium, after separation and purification to remove the bacteria protein and the residual culture medium adhered to the cellulose film to reach the bacterial dressing grade of bacterial cellulose, the bacterial cellulose accounts for The mass percentage of pure bacterial cellulose hydrogel film is 3%, and the separation and purification refers to that the secreted bacterial cellulose hydrogel film is soaked in a 5% NaOH aqueous solution at a temperature of 90°C. Heat for 3 hours, then rinse repeatedly with double distilled water until neutral. The grade of medicinal dressings refers to the hygienic s...

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Abstract

The invention discloses a bacterial cellulose compound cuprous oxide antimicrobial dressing and a preparation method thereof. The bacterial cellulose compound cuprous oxide antimicrobial dressing lies in that cuprous oxide particles are adhered into a three-dimensional porous network structure of a bacterial cellulose hydrogel film, the cuprous oxide particles are of octahedral crystal forms, and the antimicrobial dressing is obtained by soaking a bacterial cellulose hydrogel film containing a glucose solution into a NaOH water solution and copper ion water solution mixed solution and heating and pressurizing for reaction. The bacterial cellulose compound cuprous oxide antimicrobial dressing is simple and convenient in preparation process and low in cost, has not only excellent bacteria resistance but also the advantages of high water content, good air permeability, excellent degradation property, no cytotoxicity and the like, and can well meet the demand of wet-process treatment for various wounds.

Description

technical field [0001] The invention relates to a bacterial cellulose antibacterial dressing and a preparation method thereof, in particular to a bacterial cellulose composite cuprous oxide antibacterial dressing and a preparation method thereof. Background technique [0002] Skin is an important part of the human body, which plays a role in protecting the internal environment of the body and maintaining its stability. When the skin is damaged, the function and form of the limbs will be seriously affected. However, skin trauma is a common disease in modern society, and it shows a gradually increasing trend. In order to effectively treat skin wounds, people continue to seek effective treatments, and the medical community has been studying this issue. Applying dressings to treat skin wounds is one of the most basic and important methods. Wound dressings can not only cover and bandage the wound surface to temporarily protect the wound, but also have the functions and function...

Claims

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Application Information

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IPC IPC(8): A61L15/18A61L15/46A61L15/28A61L15/20A61L15/42
Inventor 陈仕艳王蕾李喆王宝秀关方怡姚晶晶刘娜王华平
Owner DONGHUA UNIV
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