Nano-level ferrous sulfate nutritional supplement micro-capsule product and preparation process thereof

A nutritional supplement, ferrous sulfate technology, applied in the direction of microcapsules, capsule delivery, food ingredients, etc., can solve the problems of product shelf life and nutritional value, accelerate the oxidation speed of ferrous ions, reduce nutritional value and other problems, and achieve a metallic taste Good covering effect, improved acceptability and reduced production cost

Active Publication Date: 2016-04-13
NAT INST FOR NUTRITION & HEALTH CHINESE CENT FOR DISEASE CONTROL & PREVENTION +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This type of product mainly has the following deficiencies: First, the size of microcapsules is generally large, ranging from tens of microns to hundreds of microns, and the particle size is not uniform, which limits its effective absorption in the intestinal mucosa to a certain extent; secondly , the inherent high temperature link in the spray drying process will partially accelerate the oxidation rate of ferrous ions, resulting in a decrease in the nutritional value of the product; The characteristics are poor, so that after such products are brewed with water or in the environment of the human stomach, the wall material will quickly disintegrate and release the embedded ferrous ions prematurely, which will also seriously affect the taste of the product
Furthermore, in the microencapsulation process similar to ferrous sulfate, there are generally problems such as relatively thin embedded wall materials and unavoidable wall material pores, which will also accelerate the contact of ferrous ions with the outside world and be oxidized, making The shelf life and nutritional value of the product is affected

Method used

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  • Nano-level ferrous sulfate nutritional supplement micro-capsule product and preparation process thereof
  • Nano-level ferrous sulfate nutritional supplement micro-capsule product and preparation process thereof
  • Nano-level ferrous sulfate nutritional supplement micro-capsule product and preparation process thereof

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Experimental program
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Effect test

Embodiment 1

[0040] (1) Inner water phase W 1 Preparation: Weigh 0.1g of water-soluble ascorbic acid, add it to 100ml of 20% ferrous sulfate aqueous solution, stir magnetically in a dark environment until well mixed;

[0041] (2) Internal oil phase O 1 Preparation of Span 80: Weigh 0.1g of Span 80, add it to 100ml of commercially available saturated edible oil, and stir until evenly mixed;

[0042] (3) External water phase W 2 Preparation: Weigh 0.1g of sucrose fatty acid ester (SE-15), add it to 100ml of 2% sodium alginate aqueous solution, and stir until uniform;

[0043] (4) Outer oil matching O 2 Preparation: Weigh 1g of polyglycerol fatty acid ester (PO-5S), add it to 100ml of sunflower oil, and stir until evenly mixed;

[0044] (5) Preparation of calcium chloride curing agent: Add 5ml of calcium chloride aqueous solution with a mass ratio of 5% to 30ml of the outer oil phase in step (4), and ultrasonically emulsify for 2min under the condition of setting the power at 30%;

[004...

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Abstract

The invention relates to a nano-level ferrous sulfate nutritional supplement micro-capsule product and a preparation process thereof. The preparation process includes firstly, preparing stable four-phase multiple emulsion by means of three times of premix membrane emulsification; secondly, preparing wall material based on sodium alginate through twice curing process by respectively adding calcium chloride and chitosan into the four-phase multiple emulsion. With particle size controlled within the nano level, the ferrous sulfate nutritional supplement micro-capsule products prepared by the process are uniform in size, have the advantages such as slow release, enteric coating, effective absorption and low production cost, and are particularly applicable to large range of food nutrition enrichment and prevention of iron deficiency anemia.

Description

technical field [0001] The invention relates to microencapsulation technology in the field of food processing and strengthening, in particular to a nano-scale ferrous sulfate nutritional supplement microcapsule and a preparation process thereof. Background technique [0002] Adults contain about 3-4g of iron, which is mainly concentrated in hemoglobin, myoglobin, transferrin and various enzymes. The most basic physiological function of iron is to combine with oxygen and transport it to various tissues of the body. The iron contained in the enzymes in the mitochondria is mainly involved in energy metabolism, and other iron-containing enzymes are also involved in the metabolism and regulation of various pathways. These include protein and lipid metabolism. Just because iron is widely involved in various metabolisms, iron deficiency will trigger a variety of chain reactions that are harmful to the body. Iron deficiency can occur in various periods, but due to special physiolo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/26A61K9/50A61K47/36A61K47/44A61P3/02A23L33/00
CPCA23V2002/00A61K9/5036A61K33/26A61K47/44A23V2200/30A23V2250/1592A23V2250/511A23V2250/51
Inventor 霍军生王连艳黄建杨婷媛张贵锋刘辉张博
Owner NAT INST FOR NUTRITION & HEALTH CHINESE CENT FOR DISEASE CONTROL & PREVENTION
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