Composition for improving treating or preventing constipation comprising Cassia fermented by lactic acid bacteria as an active ingredient and preparation method thereof

A cassia seed lactic acid bacterium and its manufacturing method are applied in the field of constipation improvement, treatment or prevention composition and its manufacture with the cassia seed lactic acid bacterium fermented product as an active ingredient, which can solve the problem that the effect cannot be fully verified scientifically, the reliability of the product is low, Can not solve the fundamental problem of constipation improvement, etc., to achieve the effect of improving constipation treatment, high safety, and less possibility of side effects

Inactive Publication Date: 2016-04-20
HEANAM NATURAL FARMING ASSOC COOPERATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, so far, various medicines and health functional foods for treating or improving constipation are being sold, but most of the medicines use stimulant medicines containing anthraquinone derivatives such as senna and rhubarb, so there are abdominal pain, Diarrhea and other side effects, and there are problems in taking or continuing to take during pregnancy. As far as health functional foods are concerned, most of their effects cannot be fully verified scientifically, and the fundamental problem of constipation improvement cannot be solved. The reliability of the product is low

Method used

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  • Composition for improving treating or preventing constipation comprising Cassia fermented by lactic acid bacteria as an active ingredient and preparation method thereof
  • Composition for improving treating or preventing constipation comprising Cassia fermented by lactic acid bacteria as an active ingredient and preparation method thereof
  • Composition for improving treating or preventing constipation comprising Cassia fermented by lactic acid bacteria as an active ingredient and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

manufacture example 1

[0074] Production example 1: Production of cassia seed hot water extract

[0075] The cassia seeds are selected from the Korean cassia (Cassiatora L.) purchased from the Jeonnam Herbal Medicine and Agriculture Cooperative Association (Hwasun-gun). After washing, they are uniformly crushed with a grinder to produce cassia seed powder with an average particle diameter of 300 μm, which is stored and used in refrigeration.

[0076] Put distilled water 10 times the weight of the pulverized cassia seeds into a reflux extractor, extract twice at 100°C for 3 hours, then cool, filter, concentrate with a vacuum concentrator, and freeze-dry to obtain a cassia seed hot water extract powder. The yield was 2.2%.

manufacture example 2

[0077] Production Example 2: Production of Semen Cassiae Ethanol Aqueous Extract

[0078] Add 50% by weight alcohol (ethanol aqueous solution) that is 4 times the weight of the pulverized cassia seeds of the above-mentioned Production Example 1, extract at room temperature for 3 days, filter, concentrate with a vacuum concentrator, and freeze-dry to obtain a cassia seed ethanol aqueous solution extract. powder. The yield was 9.8%.

manufacture example 3

[0079] Production example 3: Production of cassia seed water dilution

[0080] The pulverized cassia seeds of Production Example 1 and water were mixed so that the cassia seeds became 7% by weight, and an aqueous dilution of cassia seeds was produced.

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Abstract

The invention relates to a composition for improving treating or preventing constipation comprising Cassia fermented by lactic acid bacteria as an active ingredient and a preparation method thereof. The Cassia fermented by lactic acid bacteria can used for a long time, is high in safety, and is low in side effect when be used as a crude drug. The Cassia fermented by lactic acid bacteria has an effect that more than one of the excrement amount, the moisture content and the excrement weight is increased, the effect is the same as that of a commercial Dulcolax-S with sennoside or bisacodyl and docusate sodium as the active ingredient, the commercial Dulcolax-S is an irritant constipation therapeutic agent and is forbidden to be used for health care foods due to the side effect. Thus, the Cassia fermented by lactic acid bacteria can be applied to pharmaceutical compositions for constipation treatment or prevention, or health care foods for constipation improvement or prevention. Furthermore, the Lactobacilluskefiri MJ90 bacterial strain is beneficial to the preparation of Cassia fermented by lactic acid bacteria for improving treating or preventing constipation.

Description

technical field [0001] The invention relates to a health functional food for improving or preventing constipation, a pharmaceutical composition for treating or preventing constipation, and a method for producing a fermented product of lactic acid bacteria cassia that increases the water content and weight of feces. Moreover, this invention relates to the manufacturing method of the said cassia lactic acid bacteria fermentation product, and the strain used for it. Background technique [0002] Constipation is medically defined as constipation when defecating less than 3 times a week or defecating less than 30g a day. Under normal conditions, feces are formed and excreted 24 hours after ingesting food, but people with constipation defecate once every few days or even every day, but the amount is small, and as a result, the intestinal retention time of the ingested food becomes longer. [0003] Causes of constipation include low colon motility due to ignoring breakfast, insuff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/30A61K36/482A61P1/10C12N1/20A61K35/744C12R1/225
CPCA23L33/105A61K36/482A23V2002/00A23V2200/3202A61K2236/19A23V2400/11A23V2400/31A23V2400/51
Inventor 黄相德龙金述龙周炫龙周善宋龙寿
Owner HEANAM NATURAL FARMING ASSOC COOPERATION
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