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Oral preparation of probiotics as well as preparation method thereof

A technology of oral preparations and probiotics, which is applied in the field of oral preparations of probiotics and its preparation, can solve the problems of short medicinal effect, unstable quality, and low number of viable bacteria, and achieve stable product quality, long-lasting drug effect, and viable bacteria high number of effects

Inactive Publication Date: 2016-06-15
西安木本贞生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many types of probiotic-related products on the market, but the quality is generally unstable, the number of viable bacteria is low, and they are quickly inactivated after being exposed to the air, and the medicinal effect is short.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] To achieve the above object, the present invention provides a probiotic oral preparation, the weight percentage of each component is: 6% of Bifidobacterium infantis powder, 6% of Lactobacillus acidophilus powder, 6% of Enterococcus faecalis powder, wax Bacillus-like bacteria powder 6%, attapulgite 6%, fresh orange concentrated powder 20%, lactobacillus spray-dried powder 20%, porous starch 30%.

[0025] The present invention also provides a preparation method of probiotic oral preparation, comprising the following steps:

[0026] Step (1): Purify the attapulgite, soak the attapulgite in deionized water for 20 hours, use ultrasonic ultrasound for 40 minutes, let it stand for stratification, take the attapulgite suspension in the middle layer, vacuum freeze-dry at -30°C, grind , sieve, reserve;

[0027] Step (2): Prepare porous starch, medical starch is dried at 35°C, and crushed to obtain pregelatinized starch; the pregelatinized starch is prepared into an emulsion, and...

Embodiment 2

[0032] To achieve the above object, the present invention provides a probiotic oral preparation,

[0033] The weight percentage of each component is: 4% of Bifidobacterium infantis powder, 4% of Lactobacillus acidophilus powder, 4% of Enterococcus faecalis powder, 4% of Bacillus cereus powder, 6% of attapulgite, and concentrated fresh orange 20% powder, 20% spray-dried lactobacillus powder, and 38% porous starch.

[0034]The present invention also provides a preparation method of probiotic oral preparation, comprising the following steps:

[0035] Step (1): Purify the attapulgite, soak the attapulgite in deionized water for 28 hours, use ultrasonic ultrasound for 60 minutes, let it stand for stratification, take the attapulgite suspension in the middle layer, vacuum freeze-dry at -40°C, grind , sieve, reserve;

[0036] Step (2): Prepare porous starch, medical starch is dried at 45°C, and crushed to obtain pregelatinized starch; the pregelatinized starch is prepared into an e...

Embodiment 3

[0041] In order to achieve the above object, the present invention provides a probiotic oral preparation, each component and percentage by weight are: 3% of Bifidobacterium infantis powder, 3% of Lactobacillus acidophilus powder, 3% of Enterococcus faecalis powder, 3% of Bacillus cereus powder, 6% of attapulgite, 20% of fresh orange concentrated powder, 20% of lactobacillus spray-dried powder, and 42% of porous starch.

[0042] The present invention also provides a preparation method of probiotic oral preparation, comprising the following steps:

[0043] Step (1): Purify the attapulgite, soak the attapulgite in deionized water for 25 hours, use ultrasonic ultrasound for 50in, let it stand for stratification, take the attapulgite suspension in the middle layer, vacuum freeze-dry, the drying temperature is -25°C, Grind, sieve, reserve;

[0044] Step (2): Prepare porous starch, medical starch is dried at 40°C, crushed to obtain pregelatinized starch; the pregelatinized starch is...

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PUM

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Abstract

The invention discloses an oral preparation of probiotics as well as a preparation method thereof. The oral preparation comprises the following components in percentages by weight: 3-6% of Bifidobacterium infantis powder, 3-6% of Lactobacillus acidophilus powder, 3-6% of Enterococcus faecalis powder, 3-6% of Bacillus cereus powder, 3-6% of attapulgite, 10-20% of fresh orange concentrate powder, 10-20% of Lactobacillin spray dry powder, and 30-60% of porous starch. The probiotics are embedded in cavity of porous starch, and the product has the advantages of large number of live bacteria, stable quality, improved structure of intestinal flora, effects for inhibiting pathogen, long storage life, lasting drug effects, and substantial effects for adaptation diseases.

Description

technical field [0001] The invention relates to a probiotic oral preparation and a preparation method thereof. Background technique [0002] At present, antibiotics have become the first choice of doctors and patients when adults or children are sick. However, extensive use of antibiotics will bring strong toxic side effects and directly damage the body, especially for children's hearing. The most serious side effect of antibiotics is allergic reaction. Studies have shown that each antibiotic has different degrees of harm to the human body. For example, streptomycin and kanamycin can cause dizziness, tinnitus, and deafness; gentamicin, kanamycin, and vancomycin can damage the kidneys and so on. The ear is most sensitive to the side effects of antibiotics. For example, streptomycin, gentamicin, and kanamycin are most likely to affect ear hair cells, resulting in hearing loss; excessive use of antibiotics will cause bacteria to develop drug resistance, making antibiotics les...

Claims

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Application Information

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IPC IPC(8): A23L33/135A23L33/125A23L2/39
CPCA23L2/39A23V2002/00A23V2400/529A23V2400/113A23V2200/30
Inventor 郗伟
Owner 西安木本贞生物科技有限公司
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