Amniotic fluid detection indicator composition, preparation thereof and corresponding amniotic fluid detection pad

Abstract

The invention discloses an amniotic fluid detection indicator composition, preparation thereof and a corresponding amniotic fluid detection pad. The amniotic fluid detection indicator composition is used by taking one or two of water, ethyl alcohol, acetone and N,N-dimethylformamide as a solvent or solvents, taking one or more than one of pulullan, sodium alginate, ethyl cellulose and sodium carboxymethylcellulose as a film-forming agent or film-forming agents, taking dioctyl phthalate as a plasticizer, taking ethylene glycol, glycerol and glycol ethylene ether as wetting agents, taking bromothymol blue sodium salt, bromoxylenol blue, sodium alizarine sulfonate and bromcresol purple as indicators, preparing an amniotic fluid detection indicator at the normal temperature, then coating a medical sanitary pad with the amniotic fluid detection indicator, and drying the medical sanitary pad to prepare an amniotic fluid detection pad. The amniotic fluid detection indicator composition is convenient to use, not easy to decolor and more easily acceptable to patients, and is capable of distinguishing amniotic fluid and urine; the whole process is simple to operate; the large-scale production is easy to implement.

Description

Technical field [0001] The invention belongs to the field of medical dressings, and relates to an amniotic fluid detection indicator composition, a preparation method thereof and a corresponding amniotic fluid detection pad. Background technique [0002] Rupture of fetal membranes (ROM) may occur at any time during pregnancy. Normally, it ruptures during full-term delivery. However, if there is an accident that ruptures prematurely before delivery, it will cause all kinds of pain to pregnant women. The rupture of the membranes before full-term delivery is called premature rupture of membranes or PROM; under normal circumstances, the incidence of premature rupture of membranes after 37 weeks of gestation is about 10%, and the incidence of ROM before 37 weeks of gestation is 2 3.5%, called PPROM. PROM is a major cause of pre- and post-natal complications, and it is the main cause of complications in newborns who must be admitted to NICU and premature delivery. Because medical sta...

AI Technical Summary

Problems solved by technology

However, the amount of amniotic fluid leakage is small, and the amniotic fluid for evaluation may not be visible in the vagina, and the amniotic fluid may also be contaminated with urine, cervical mucus, vaginal secretions, blood, or meconium, which may cause detection errors

Patent CN201220572286.7 discloses a protective pad for amniotic fluid detection. The pH test paper is placed in the protective pad, and whether the amniotic fluid leaks is detected by detecting the pH change of the vaginal transudate. However, when the vaginal transudate contains urine, the pH test paper remains the same. It may change color, so it is impossible to distinguish amniotic fluid and urine, which is easy to cause misjudgment, and the pH test paper is easy to decolorize when it encounters urine or amniotic fluid, thus contaminating the skin and clothing in contact

Patent CN201520302623.4 discloses a health care pad for amniotic fluid detection, which uses anthocyanin as an indicator to determine whether amniotic fluid leaks by detecting the pH change of vaginal fluid, but this method still cannot distinguish between amniotic fluid and urine, and the color changes Not obvious, easy to cause misjudgment

Patent CN03824113.7 discloses a device and method for detecting amniotic fluid in vaginal secretions. The PAMG-1 detection antibody is used to detect a small amount of amniotic fluid in the vagina. The detection method has high sensitivity, but the detection swab generally needs to penetrate 5-7cm into the vagina , easy to bring discomfort to pregnant women, and there is a certain risk

Images