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Multifunctional Compound Skin Or Wound Dressing As Regenerative Skin Substitute

An alternative, multi-functional technology, applied in the direction of medical science, prosthesis, coating, etc., to achieve the effect of reducing scar formation, quick and easy to use, and accelerated healing

Inactive Publication Date: 2016-11-09
杭州弘复医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] On the other hand, overstimulation of fibroblasts or excessive deposition of collagen due to desiccation of the wound bed can lead to extensive scarring with profound functional and aesthetic consequences for the patient

Method used

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  • Multifunctional Compound Skin Or Wound Dressing As Regenerative Skin Substitute
  • Multifunctional Compound Skin Or Wound Dressing As Regenerative Skin Substitute
  • Multifunctional Compound Skin Or Wound Dressing As Regenerative Skin Substitute

Examples

Experimental program
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Effect test

example 1

[0175] image 3 Showing the treatment of a patient with a burn wound using an example of the dressing material of the present invention: Male, 10 years old; deep 2nd degree burn on left ankle caused by boiling water; treated with a burn ointment for 4 days but condition worsened followed by dressing of the present invention Examples of materials were treated and the dressing was changed every 1-2 days. image 3 A shows that there is a large amount of necrotic tissue and eschar on the wound before treatment, and the wound and surrounding tissues are red, swollen and inflamed. Application of the embodiment of the dressing material of the present invention after 1 day of treatment, the wound surface eschar is basically liquefied through autolytic debridement ( image 3 B), after washing with normal saline, the wound tends to be clean, leaving only a thin layer of scab ( image 3 C), the inflammation of the wound surface and surrounding tissues obviously subsided. After 14 days...

example 2

[0177] Figure 4 Showing the treatment of a patient with a burn wound using an embodiment of the dressing material of the present invention: male, 1 year and 5 months; deep 2nd to 3rd degree burns on the right forearm and hand caused by boiling water; treated with a burn ointment for 16 days but the condition Aggravated (exacerbated by tissue necrosis during winter exposure to the open air) and had a high fever for several days; subsequently treated with an embodiment of the dressing material of the present invention, and the dressing was changed every 1-2 days. Figure 4 A shows that the wound surface is covered with a large amount of necrotic tissue and hard eschar before treatment, and the wound surface and surrounding tissues are severely red, swollen and inflamed, accompanied by systemic inflammatory response. Application of the embodiment of the dressing material of the present invention is through 1 day of local treatment, and after supplemented with systemic antibacter...

example 3

[0179] Figure 5 , 6It shows that the embodiment of the dressing material of the present invention is used to treat the mother and two patients who were scalded by boiling water at the same time: the mother, 32 years old; the right foot and ankle were deeply scalded by boiling water; two kinds of burn ointment were used for 18 days but the condition worsened, and the level of injury deepened to become a 3rd degree wound. Subsequent treatments were performed with embodiments of the dressing material of the present invention and the dressing was changed every 1-2 days. Figure 5 A shows that there is a large amount of necrotic tissue, eschar, ulceration under the scab on the wound before treatment, and the wound and surrounding tissues are red, swollen and inflamed. Application of the embodiment of the dressing material of the present invention After 1 day of treatment, the wound surface eschar basically softens and liquefies, and after washing with physiological saline to rem...

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Abstract

Provided is a new bionic skin material with multiple functions and a high efficacy. With a compound microporous fibre net structure, the material imitates a skin barrier function, has anti-fouling properties, hygroscopic properties, moisture retention properties, air permeability, flexibility and adhesiveness, and can effectively absorb wound exudate and residues for rapid painless autolysis and debridement, ensure sufficient drainage by bidirectional regulation, maintain a semi-closed, local physiological wet environment favorable for the reparative metabolism and physiological healing of a wound, inhibit inflammation, reduce exudation, benefit the response inside and outside of cells, promote the migration of fibroblasts and epithelial cells of the body itself and the regeneration of granulation tissue and epithelial cells of the wound, accelerate the physiological healing and recovery of the wound, and reduce recurrences. It has been clinically proved that the dressing material can accelerate the healing of acute skin injuries and chronic ulcer wounds, achieve a high healing quality, avoid or reduce traumatic skin grafting to the greatest extent, reduce the pain of patients and the production of scars, and restore the physiological function and appearance of the body.

Description

[0001] The present application claims priority to U.S. Provisional Patent Application No. 62 / 168,124, filed May 29, 2015, and U.S. Provisional Patent Application No. 62 / 168,184, filed May 29, 2015 The priority of these two earlier applications is hereby incorporated by reference. technical field [0002] The present invention relates to a kind of skin or wound surface protection and healing material, and its preparation method and application method, especially relate to multifunctional skin or wound surface dressing as regenerative skin substitute and its application in regenerative medicine, wound rescue, wound care, medical cosmetology applications in other fields. Background technique [0003] Wound healing is a very well-organized and complex process. Acute wound healing usually follows a well-defined process, which is described as follows: coagulation; inflammation; cellular proliferation and repair of the matrix; epithelialization and reconstruction of scar tissue. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/50A61L27/00A61L27/56A61L27/60
CPCA61L27/00A61L27/50A61L27/56A61L27/60A61L27/446A61L15/18A61L15/225A61L15/425A61L15/52A61L2300/606A61L2420/02A61L2420/06
Inventor 陈晓英熊光明
Owner 杭州弘复医疗科技有限公司
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