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A kind of pure natural water-soluble human body lubricant and its preparation method and application

A human body lubricant and water-soluble technology, applied in the field of pure natural water-soluble human body lubricant and its preparation, can solve the problems of increasing the irritation of medical devices to mucous membranes, poor stability of silicone, easy accumulation of ecological environment, etc., and achieve excellent lubrication Good performance, improved performance, good stability

Active Publication Date: 2020-03-17
SHANGHAI YUKING WATER SOLUBLE MATERIAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is a relatively good method for preparing water-soluble gel lubricants, but it can also be seen from the formula that the raw materials used are mainly water-soluble polymers synthesized by polymers, and the gel matrix used is carbomer. Carbomer can only become a gel under alkaline conditions, so sodium hydroxide or potassium hydroxide needs to be added to adjust the lubricant to alkaline, but sodium hydroxide or potassium hydroxide will increase the irritation of medical devices to the mucous membrane
[0006] U.S. Patent No. 5,688,747 discloses a method for preparing a water-based lubricant for the surface treatment of catheters and other medical devices using silicone as a lubricating component. The main disadvantage is that silicones have poor stability and are easy to accumulate in the environment. ecological environment damage

Method used

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  • A kind of pure natural water-soluble human body lubricant and its preparation method and application
  • A kind of pure natural water-soluble human body lubricant and its preparation method and application
  • A kind of pure natural water-soluble human body lubricant and its preparation method and application

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0047] Preparation of plant extract lubricating fluid:

[0048] 1) The plant raw materials are cleaned with sterile water, air-dried, and pulverized by a high-speed pulverizer to obtain a coarse powder. Add sterile water twice the mass of the coarse powder to the coarse powder, soak for 24 hours, and then filter with a 300-mesh filter , to obtain the initial extract;

[0049] 2), using a microporous filter membrane with a pore size of 0.8 μm to filter the initial extract in step 1), filter out mechanical particles, and obtain a plant extract;

[0050] 3) Reverse osmosis is used to purify the plant extract in step 2), and impurities such as water and anthocyanin are selectively removed to obtain a plant extract lubricant.

Embodiment 1-7

[0051] Embodiment 1-7: the preparation of pure natural water-soluble human body lubricant

[0052] The concrete preparation steps of pure natural water-soluble human body lubricant are as follows:

[0053] 1) Vacuumize the vacuum gel reaction kettle filled with sterilized deionized water, add the formula gelling agent and emulsifier in turn under continuous stirring, control the vacuum degree to 0.1MPa, and control the temperature to 60℃~80℃ , the rotating speed is 500r / min, stirring for 3h, so that the gelling agent and emulsifier are completely dissolved;

[0054] 2) Weigh the plant extract lubricating liquid, thickener, pure honey and conditioning agent into the vacuum gel reaction kettle in sequence, keep the vacuum state during the feeding process, reduce the speed to 300r / min, and control the temperature at 60 ℃ ~ 80 ℃ heat preservation reaction for 5 hours, fully stirred until completely mixed uniformly, the vacuum degree in the reaction kettle is controlled to 0.1MPa ...

Embodiment 8

[0060] Embodiment 8: irritation and lubricity test

[0061] Use the pure natural water-soluble human body lubricant prepared by the embodiments of the present invention 1-7 and the conventional human body lubricant to carry out comparative tests respectively, and detect the irritation of the catheter coated with lubricant to the body cavity mucosa and the penetration and penetration of the catheter. Traction force, irritation score and force size (unit N) are shown in Table 3 and Table 4:

[0062] Table 3: Irritation test results

[0063]

[0064] Table 4: Penetration and traction test results

[0065]

[0066] As can be seen from the results of Table 3 and Table 4, the irritation score, penetration force and traction force of the catheter coated with the pure natural water-soluble personal lubricant of the present invention are significantly lower than those of the control group. The irritation of the pure natural water-soluble human body lubricant of the present inve...

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Abstract

The invention provides a pure natural water-soluble human body lubricant which is prepared from the following components by weight percent: 1%-10% of gelatinizing agent, 1%-10% of emulgator, 0.5%-2% of thickening agent, 0.1-1% of pure honey, 0.5%-10% of plant extracted lubricating fluid, 0.5%-2% of conditioner and the balance of sterilized deionized water. The lubricant provided by the invention has excellent lubricating property, high stability, safety and environmental protection; the plant extracted lubricating fluid is prepared according to a three-level filtering technology of mechanical screening filtering, micro-filtration and reverse osmosis concentration purification, and the active component with the highest practical value is remained; the product performance is promoted in the manner of combining vacuumizing and heating; the pure natural water-soluble human body lubricant has multiple effects of sterilizing, diminishing inflammation, restraining inflammation diffusion, draining secreta, promoting local metabolism, converging wound, preventing lesion and tumor, and the like.

Description

technical field [0001] The invention belongs to the technical field of medical device lubricants, in particular, it relates to a pure natural water-soluble human body lubricant and its preparation method and application. Background technique [0002] During the process of medical devices (diagnostic devices such as endoscopes, colposcopes, cervical forceps, and medical catheters) entering the cavity, it is often necessary to apply an appropriate amount of lubricant on the surface of the medical device to reduce the damage of the device to human tissue. Most gynecological clinics and inpatient departments of hospitals still use light liquid paraffin oil and petroleum jelly as lubricants. Liquid paraffin oil and petroleum jelly are not only difficult to clean, but also cause certain irritation to body cavities and other tissues, and are easy to breed mold. In the past, most of the human body lubricants used in medical treatment were oily lubricants. Due to the low polarity of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/04A61L31/00A61L31/16
CPCA61L31/005A61L31/042A61L31/16A61L2300/30A61L2300/404C08L5/00C08L1/284
Inventor 王宇熊俊超
Owner SHANGHAI YUKING WATER SOLUBLE MATERIAL TECH
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