Separation and purification method of D,L-methionine

A technology for separation and purification of methionine, applied in the chemical industry, can solve problems such as energy waste and mother liquor circulation, and achieve the effects of low cost, reduced energy consumption, and simple operation

Active Publication Date: 2017-02-22
NINGXIA UNISPLENDOUR TIANHUA METHIONINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The purpose of the present invention is to provide a method for separation and purification of D,L-methionine, which can overcome the problem of circulation of potas...

Method used

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  • Separation and purification method of D,L-methionine
  • Separation and purification method of D,L-methionine
  • Separation and purification method of D,L-methionine

Examples

Experimental program
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Effect test

Embodiment 1

[0037] Take 3484.4 grams of 5-(2-methylthioethyl)-hydantoin aqueous solution and add it to the autoclave, wherein 5-(2-methylthioethyl)-hydantoin 696.88 grams (4mol) , then add 1658.4 grams of potassium carbonate aqueous solution with a mass fraction of 50%, close the autoclave, immediately raise the temperature to 180 ° C, keep the temperature for 20 minutes, and then release the pressure to normal pressure. The residual ammonia is less than 50ppm; carbon dioxide is passed into the saponified liquid after deammonification, the pressure of carbon dioxide is 0.5MPa, the neutralization temperature is 20°C, and the pH at the neutralization end point is 6.8, the crystals are suction filtered, washed with a small amount of water, and obtained The wet product of methionine is dried to obtain 415.9 grams of methionine product with a content of 99.3%; the washing water is combined with the mother liquor of suction filtration to obtain 3659.44 grams of potassium bicarbonate aqueous solu...

Embodiment 2

[0041] Take 3484.4 grams of 5-(2-methylthioethyl)-hydantoin aqueous solution and add it to the autoclave, wherein 5-(2-methylthioethyl)-hydantoin 696.88 grams (4mol) , then add 1474.13 grams of potassium carbonate aqueous solution with a mass fraction of 60%, close the autoclave, immediately heat up to 185 ° C, keep the temperature for 15 minutes, and then release the pressure to normal pressure. The residual ammonia is less than 40ppm; carbon dioxide is passed into the saponified liquid after deammonification, the pressure of carbon dioxide is 0.8MPa, the neutralization temperature is 15°C, and the pH at the neutralization end point is 6.0, the crystals are filtered by suction, washed with a small amount of water, and obtained The wet product of methionine is dried to obtain 445.65 grams of methionine product with a content of 99.3%; the washing water is combined with the mother liquor of suction filtration to obtain 3725 grams of potassium bicarbonate aqueous solution contain...

Embodiment 3

[0045] Take 3484.4 grams of 5-(2-methylthioethyl)-hydantoin aqueous solution and add it to the autoclave, wherein 5-(2-methylthioethyl)-hydantoin 696.88 grams (4mol) , then add 1474.13 grams of potassium carbonate aqueous solution with a mass fraction of 60%, close the autoclave, immediately heat up to 185 ° C, keep the temperature for 15 minutes, and then release the pressure to normal pressure. The residual ammonia of ammonia is less than 40ppm; carbon dioxide is introduced into the saponified liquid after deamination, the pressure of carbon dioxide is 0.8MPa, the neutralization temperature is 15°C, the pH of the neutralization end point is 6.0, and the crystals are filtered by suction to obtain the wet product of methionine , the obtained wet product is recrystallized, the crystals are suction filtered, and dried to obtain 312.0 grams of methionine product with a content of 99.6%. The obtained methionine product is analyzed by scanning electron microscope, as shown in figur...

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Abstract

The invention provides a separation and purification method of D,L-methionine. The separation and purification method is realized through the following steps: hydrolyzing 5-(2-methylthio-ethyl)-hydantoin through an alkaline potassium compound to obtain a potassium methionine saponified solution containing potassium carbonate, introducing carbon dioxide into the saponified solution, crystalizing and separating to obtain methionine and a potassium bicarbonate water solution containing less methionine respectively, carrying out homogeneous membrane electroosmosis, heterogeneous membrane electroosmosis and the like on the potassium bicarbonate water solution respectively. By adopting the method provided by the invention, energy consumption needed by subsequent purification and concentration can be reduced and the operation is simple; the purity of the obtained methionine reaches up to 99.4 percent, the retention rate of the methionine reaches 98.8 percent, and the salt removing rate reaches 99.5 percent; the method can avoid a condition that the methionine is decomposed after being heated for a long time to generate malodorous gas; the method is low in cost, a condition that a lot of acidic and odorous wastewater is discharged is avoided, the method is green and environment-friendly, and the separated potassium bicarbonate can be completely circulated to the step of hydrolyzing the 5-(2-methylthioethyl)-hydantoin; fresh potassium carbonate, potassium bicarbonate or potassium hydroxide does not need to be supplemented.

Description

technical field [0001] The invention belongs to the field of chemical industry, and in particular relates to a method for separating and purifying D,L-methionine. Background technique [0002] D, L-methionine, also known as methionine, is one of the basic units of protein and the only amino acid containing sulfur among the essential amino acids. In addition to participating in the transfer of methyl groups in animals, the metabolism of phosphorus and adrenaline, choline, In addition to the synthesis of creatine, it is also a raw material for the synthesis of protein and cystine. [0003] D, L-methionine is widely used in the fields of medicine, food, feed and cosmetics, among which the amount of feed additives is very large. The global demand for methionine has reached 1.8 million tons per year, and China's demand for methionine in 2015 exceeded In addition to the production of 100,000 tons of methionine produced by Ningxia Ziguang Tianhua Methionine Co., Ltd., my country al...

Claims

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Application Information

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IPC IPC(8): C07C319/28C07C323/58
CPCC07B2200/07C07C319/28C07C323/58
Inventor 吴传隆郑道敏姚如杰万霞秦岭
Owner NINGXIA UNISPLENDOUR TIANHUA METHIONINE CO LTD
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