Intravascular fluorescent-photoacoustic-ultrasonic multi-mode imaging device and method

Abstract

The invention belongs to the field of intravascular endoscope imaging and discloses an intravascular fluorescent-photoacoustic-ultrasonic multi-mode imaging device and method. The device comprises a computer, a fluorescence excitation and acquisition system, a photoacoustic signal excitation and acquisition system, an ultrasonic signal excitation and acquisition system and an integrated probe. The fluorescence excitation and acquisition system comprises a pulsed laser, a first optical filter, a collimator, a first optical fiber coupler, an optical fiber circulator, a photoelectric sliding ring, a second optical fiber coupler, a second optical filter, a photoelectric multiplier tube, a first signal amplifier and a first acquisition card. An intravascular endoscope imaging system in a fluorescent imaging mode, an intravascular endoscope imaging system in a photoacoustic imaging mode and an intravascular endoscope imaging system in an ultrasonic imaging mode are integrated, and due to combination of the advantages of the three imaging modes, structural information of multiple parameters of vessels and component information of corresponding substances can be obtained.

Description

technical field [0001] The invention relates to the research field of vascular endoscopy, in particular to an intravascular fluorescence-photoacoustic-ultrasound multimode imaging device and method. Background technique [0002] Cardiovascular and cerebrovascular diseases are diseases with a relatively high mortality rate, and the accuracy of blood vessel detection and diagnosis has higher requirements. The means of modern medicine to detect blood vessels include magnetic resonance (MRI) angiography, angiography (IVUS) and intravascular fluorescence imaging. The above detection methods can better present the external shape or internal contour and components of blood vessels. information, but cannot provide local details of the vessel wall and lumen. Intravascular fluorescence imaging is the use of injecting fluorescent substances into blood vessels and then irradiating them with laser light to generate fluorescence. By receiving fluorescence information, blood vessels can b...

AI Technical Summary

Problems solved by technology

The end of the optical fiber of this device directly emits light at 90°, the laser is divergently irradiated on the object to be measured, the laser is not converged, and there is also the problem of poor resolution of the photoacoustic image, and in the device disclosed in this technology, the coupling of the laser and the optical fiber is adopted The way of direct coupling, in this way, the deviation is very easy to occur during the rotation of the fiber, which leads to the reduction of the transmission efficiency of the laser to the fiber, and directly affects the generation of photoacoustic signals

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