Molybdenum dioxide nano photothermal conversion material and preparation method and application thereof

A technology of molybdenum dioxide and nano-materials, which is applied in the field of molybdenum dioxide nano-photothermal conversion materials and its preparation, can solve the problems of affecting light absorption effect, poor biodegradability, and high energy consumption for synthesis, and achieve excellent photothermal Stability and biocompatibility, simple and fast preparation method, high active crystallinity effect
CN106938857AActive Publication Date: 2017-07-11NANJING UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANJING UNIV OF SCI & TECH
Publication Date
2017-07-11

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Abstract

The invention discloses a molybdenum dioxide nano photothermal conversion material and a preparation method and application thereof. A high activity solvothermal precursor is obtained by laser ablation of high pure molybdenum in a mixed solution by combination of a liquid phase laser ablation technique and a solvothermal method; and molybdenum dioxide nano nanoparticles are synthesized by reaction under mild conditions by the solvothermal method. The prepared molybdenum dioxide nano nanoparticles have surface plasmon resonance properties, can produce strong light absorption in a near infrared band, can be used for effective conversion of absorbed light into heat so as to kill cancer cells under near infrared laser irradiation, have excellent photothermal stability and biological compatibility, and can be used for the preparation of a photothermal treatment reagent, the photothermal treatment reagent comprising the molybdenum dioxide nano photothermal conversion material is injected into a tumor site, tumor is irradiated by near infrared laser, the growth of the tumor can be effectively inhibited, and the molybdenum dioxide nano photothermal conversion material has wide application prospect in the field of tumor photothermal therapy.
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Description

technical field

[0001] The invention belongs to the field of photothermal conversion materials, and in particular relates to a molybdenum dioxide nanometer photothermal conversion material and its preparation method and application. Background technique

[0002] Photothermal therapy achieves the effect of treating cancer by injecting materials into tumors, using materials to absorb a large amount of light energy in the near-infrared band (biological window) and converting it into heat energy to kill cancer cells. Compared with traditional radiation therapy, chemotherapy and other cancer treatment technologies, photothermal therapy has the greatest advantage in precise treatment. It combines photothermal effect agents with antibodies, and can accurately reach around cancer cells through the targeting of antibodies. No harm to normal cells and tissues. In addition, the course of photothermal therapy is very short, just a few minutes, and has no other side effects. It is a can...

Claims

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