Quantitative glucose beverage for glucose tolerance detection test and production technology thereof

A technology of glucose and laboratory, applied in the field of quantitative glucose beverage and its production process, can solve the problems of unknown influence of glucose metabolism, no description of glucose, failure to meet clinical needs, etc., achieve accurate measurement, good taste, and ensure drug safety Effect

Inactive Publication Date: 2017-08-08
岱那生物科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Therefore, the current glucose tolerance testing method in the hospital is not accurate enough, and the inspectors need to prepare oral glucose solution, or use medical glucose solution, which cannot meet the cli

Method used

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  • Quantitative glucose beverage for glucose tolerance detection test and production technology thereof
  • Quantitative glucose beverage for glucose tolerance detection test and production technology thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: Quantitative glucose beverage production process required for the glucose tolerance test of 50g anhydrous glucose amount, formula is as follows:

[0044] 300ml / bottle 1 bottle

[0045] Anhydrous glucose 50g

[0046] Sodium benzoate 0.01~0.9g (as acid)

[0047] Citric acid amount

[0048] Sunset yellow 0.01~0.03g

[0049] Allure Red 0.01~0.03g

[0050] Appropriate amount of flavoring agent

[0051] Purified water to 300ml

[0052] production process:

[0053] Step 1: Weigh 50g of anhydrous glucose with a predetermined weight and dissolve it in 1 / 2~2 / 3 volume of purified water of 300ml of the total amount of purified water, that is, dissolve 50g of anhydrous glucose in 150~200ml of purified water, stir and heat to Anhydrous glucose is completely dissolved to obtain solution I, the stirring time is generally 10-20 minutes, and the heating temperature is 60-80°C.

[0054] Step 2: Add sodium benzoate, sunset yellow, allura red, and flavoring agents to s...

Embodiment 2

[0069] Embodiment 2: Quantitative glucose beverage production technology required for the glucose tolerance test of 50g anhydrous glucose amount, formula is as follows:

[0070] 300ml / bottle 1000 bottles

[0071] Anhydrous glucose 50000g

[0072] Sodium benzoate 10~900g (as acid)

[0073] Citric acid amount

[0074] Sunset yellow 10~30g

[0075] Allure Red 10~30g

[0076] Appropriate amount of flavoring agent

[0077] Purified water up to 300000ml

[0078] production process:

[0079] Step 1: Weigh 50,000g of anhydrous glucose with a predetermined weight, and dissolve it in 1 / 2~2 / 3 volume of purified water of 300,000ml of purified water, that is, dissolve 50,000g of anhydrous glucose in 150,000~200,000ml of purified water, stir and heat to Anhydrous glucose is completely dissolved to obtain solution I, the stirring time is generally 10-20 minutes, and the heating temperature is 60-80°C.

[0080] Step 2: Add sodium benzoate, sunset yellow, allura red, and natural season...

Embodiment 3

[0095] Embodiment 3: Quantitative glucose beverage production process required for the glucose tolerance test of 75g anhydrous glucose amount, formula is as follows:

[0096] 300ml / bottle 1 bottle

[0097] Anhydrous glucose 75g

[0098] Sodium benzoate 0.01~0.9g (as acid)

[0099] Citric acid amount

[0100] Gum Arabic 0.01~3g

[0101] Allure Red 0.01~0.03g

[0102] Appropriate amount of flavoring agent

[0103] Glycerin abietic acid ester (rosin glyceride) 0.01~0.03g

[0104] Purified water to 300ml

[0105] production process:

[0106] Step 1: Weigh 75g of anhydrous glucose with a predetermined weight and dissolve it in 1 / 2~2 / 3 volume of purified water of 300ml of the total amount of purified water, that is, dissolve 75g of anhydrous glucose in 150~200ml of purified water, stir and heat to Anhydrous glucose is completely dissolved to obtain solution I, the stirring time is generally 10-20 minutes, and the heating temperature is 60-80°C.

[0107] Step 2: Add sodium b...

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Abstract

The invention provides a quantitative glucose beverage for glucose tolerance detection test and a production technology thereof. The quantitative glucose beverage is prepared from 100 to 400ml of purified water, 25g or 50g or 75g or 100g of anhydrous glucose, and 0.1 to 10g of non-sugar additive, wherein the non-sugar additive is selected from one or several of a preservative, an acidulant, a flavoring agent, a coloring agent, an emulsifier and a thickener. The quantitative glucose beverage has the advantages that the added components of non-sugar additive are clear, the purity is higher, and the obtained quantitative glucose beverage for glucose tolerance detection test has the advantages of sterility, accurate metering, good mouth feel, high safety property and the like; no sugar is introduced, so that the influence to the result is avoided; while the safety of medicines or apparatuses or foods is guaranteed, the liquid has a pleasant color, so that the purposes of flavoring and coloring are realized; by adding the thickener, the retention time of the glucose beverage in digestive tracts is effectively prolonged, and the digestion function of a patient is restored.

Description

technical field [0001] The invention relates to the field of pharmaceutical manufacturing, in particular to a quantitative glucose beverage required for a glucose tolerance test and a production process thereof. Background technique [0002] Glucose tolerance test, also known as Oral glucose tolerance test (OGTT), is a medical experiment to test the metabolism level of blood sugar in the human body. The specific steps are that the subjects are required to measure the fasting blood glucose level under fasting conditions, then drink 75g of glucose, and then detect the changes of blood glucose in 30 minutes, 1 hour, 2 hours and 3 hours respectively. Children are calculated at 1.75g / kg, but not more than 75g. According to the standards promulgated by the World Health Organization, if the blood glucose is higher than 11.1mmol / L after 2 hours in the glucose tolerance test, it can be diagnosed as diabetes. [0003] Glucose that can be used by organisms is dextrose, molecular form...

Claims

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Application Information

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IPC IPC(8): A23L2/38A23L2/52G01N1/28
CPCA23L2/38A23L2/52A23L2/56A23L2/58G01N1/28A23V2002/00A23V2200/10A23V2200/04A23V2200/16A23V2200/222A23V2200/242A23V2250/032A23V2250/5114A23V2250/5028A23V2250/1614
Inventor 周强华徐晋
Owner 岱那生物科技(上海)有限公司
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