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A method for co-processing of echinocandin bacteria residue and sludge mixed wet anaerobic digestion

An echinocandin and anaerobic digestion technology, which is applied in biological sludge treatment, pyrolysis sludge treatment, fermentation, etc., can solve the problems of large equipment footprint, low treatment efficiency, and large resource consumption, and achieve sustainable Effects of improving biochemical properties, improving nutrient ratio, and reducing residual risk

Active Publication Date: 2021-02-09
NANJING AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods generally have disadvantages such as large resource consumption, low processing efficiency, large odor, and large equipment footprint in engineering applications.
So far, there are no successful examples of modification and disposal of echinocandin residues at home and abroad

Method used

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  • A method for co-processing of echinocandin bacteria residue and sludge mixed wet anaerobic digestion
  • A method for co-processing of echinocandin bacteria residue and sludge mixed wet anaerobic digestion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] (1) Alkali-thermal modification of echinocandin bacteria residue

[0026] Get 2L of echinocandin bacterial residue (pH value 7.1, water content 97%, volatile solid VS 92.5%, crude protein 38.1%, crude fiber 8.91%, crude fat 2.01%) of certain biopharmaceutical factory; With 0.05g ( NaOH) / g(TS) ratio was added to NaOH, then treated in a 70°C water bath for 2h, cooled to room temperature, and set aside.

[0027] (2) thermal hydrolysis of sludge

[0028] Take 1L of sewage biochemical treatment sludge (pH value 6.75, water content 96.5%, VS 56.2%), put the sludge in a high-temperature cooking pot at 121°C for 30 minutes, cool to room temperature, and set aside.

[0029] (3) Mixing of bacteria residue and sludge

[0030] The echinocandin bacterial residue modified by step (1) and the sludge thermally hydrolyzed in step (2) are uniformly mixed at a volume ratio of 2:1 to obtain a mixed material of bacterial residue and sludge.

[0031] (4) Anaerobic digestion to produce bio...

Embodiment 2

[0045] (1) Alkali-thermal modification of echinocandin bacteria residue

[0046] Take 3L of echinocandin bacteria residue (pH value 7.3, water content 96%, VS 93.7%, crude protein 49.3%, crude fiber 1.79%, crude fat 5.23%) from a biopharmaceutical factory. Add NaOH at a ratio of 0.08g(NaOH) / g(TS), then treat in a water bath at 80°C for 1h, and cool to room temperature for use.

[0047] (2) thermal hydrolysis of sludge

[0048] Take 1L of sewage biochemical treatment sludge (pH value 6.5, water content 97.2%, VS 52%), and put the sludge in a high-temperature cooking pot at 150° C. for 15 minutes for hydrolysis. Cool to room temperature and set aside.

[0049] (3) Mixing of bacteria residue and sludge

[0050] The echinocandin bacterial residue modified by step (1) and the sludge thermally hydrolyzed in step (2) are uniformly mixed at a volume ratio of 3:1 to obtain a mixed material of bacterial residue and sludge.

[0051] (4) Anaerobic digestion to produce biogas

[0052]...

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Abstract

The invention discloses a method for mixed wet anaerobic digestion co-processing of echinocandin slag and sludge. Anaerobic digestion realizes the co-processing of two types of organic waste. Through alkali-thermal modification, the echinocandin bacteria residue is rapidly broken, the cytoplasm is dissolved, the long-chain organic matter is hydrolyzed into short-chain organic matter, and the biodegradability of the bacteria residue is improved. Moreover, the reasonable compatibility of bacterial residue and sludge changes the nutrient ratio of the anaerobic digestion system, ensures the activity of methane bacteria, and significantly improves the anaerobic digestion rate and gas production. The echinocandin basically has no residue after being treated by the method of the invention, and has remarkable environmental protection benefit and economic benefit.

Description

technical field [0001] The invention belongs to the technical field of solid waste treatment, and relates to a method for harmless treatment of echinocandin slag, in particular to a method for co-processing of mixed wet anaerobic digestion of echinocandin slag and sludge. Background technique [0002] Echinocandin is a natural microbial product discovered in the 1970s. It is a new class of lipopeptide antifungal drugs. It has broad antibacterial spectrum, strong antibacterial effect, long half-life, few and mild adverse reactions, and is widely used in clinical practice. . According to statistics, the production of echinocandin source drugs in my country accounts for more than 70% of the world. However, in the process of biosynthesis and extraction of echinocandins, a type of hazardous waste—bacteria residue (classified as HW02 medical waste in the National Catalog of Hazardous Wastes) will be produced. The main components of echinocandin slag are mycelium, remaining mediu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P5/02C02F11/10C02F11/04
CPCC02F11/04C02F11/10C12P5/023Y02E50/30
Inventor 方迪白雪
Owner NANJING AGRICULTURAL UNIVERSITY