Extraction method for ferulic acid in rice bran meal

Abstract

The invention discloses an extraction method for ferulic acid in rice bran meal. According to the method, cross-linking fixation is carried out on biomagnetic nanometer materials such as magnetosome and feruloyl esterase by adopting transglutaminase so as to obtain immobilized feruloyl esterase, then ferulic acid ester in rice bran meal after rice bran oil is extracted is pretreated by adopting the immobilized feruloyl esterase, extraction is carried out by using isopropyl alcohol after pretreatment, after solid-liquid separation of the extracting solution, then microfiltration and nanofiltration two-stage decontamination and low-temperature vacuum concentration are adopted, and activated carbon decoloration and recrystallization carried out on concentrated solution, so that a ferulic acid product with the purity of more than 98% is obtained. Natural ferulic acid is extracted from rice bran meal by adopting the immobilized feruloyl esterase, so that the problems of environmental pollution, low safety and high industrialized production cost existing in the prior art are overcome, and the extraction method has preferable application prospects.

Description

technical field

[0001] The invention belongs to the technical field of extracting ferulic acid, and in particular relates to a method for extracting ferulic acid with a purity of ≥98% from rice bran meal after extracting rice bran oil. Background technique

[0002] Sodium ferulate is widely found in Chinese herbal medicines such as Ferulicum, Angelica, Chuan Shao, Cimicifuga, Semen Jujuba, and food materials such as coffee, chaff, vanilla beans, wheat drums, and rice bran. It has anti-platelet aggregation, inhibits platelet The formation of thromboxane, the enhancement of prostaglandin activity, analgesia, and the relief of vasospasm are the basic raw materials for the production of drugs for the treatment of cardiovascular and cerebrovascular diseases and leukopenia. Studies in recent years have found that many ferulic acid and its derivatives have pharmacological effects and biological activities such as anti-inflammatory and anti-aging, and have low toxicity, so they are ...