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Flaxseed preparation for detoxification, effect enhancement and anti-oxidation and preparation method thereof

A technology of linseed and linseed oil, which is applied in the field of medicine, can solve the problems of complex mutual influence factors, many components, unfavorable preparation and storage of preparations, achieve uniform appearance, simple preparation method, and improve the effect of antioxidant capacity

Active Publication Date: 2018-10-12
江西樟树市正康医药生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although the antioxidant preparations disclosed in the prior art have a certain antioxidant effect, they often have many components and complex interaction factors, which are not conducive to the preparation and storage of the preparations.

Method used

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  • Flaxseed preparation for detoxification, effect enhancement and anti-oxidation and preparation method thereof
  • Flaxseed preparation for detoxification, effect enhancement and anti-oxidation and preparation method thereof
  • Flaxseed preparation for detoxification, effect enhancement and anti-oxidation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Flaxseed self-emulsifying powder formulation: linseed oil 13% by weight, flax lignans 4% by weight, vitamin C 2.5% by weight, xylitol 2.0% by weight, Tween 80 8.0% by weight, glycerin 11.5% by weight, p-hydroxybenzene 0.15% by weight of methyl formate and 58.85% by weight of lactose.

[0021] Preparation steps: heat and mix Tween 80 and glycerin at 35°C, then add linseed oil, linseed lignan, xylitol, vitamin C, and methyl p-hydroxybenzoate, stir and mix evenly, and cool to room temperature. Form concentrated oily milk, then add lactose, mix to form powder, that is. The powder was completely dispersed in 500ml of water at 37°C until it became a uniform and clear liquid, and the microemulsion particle size was 26.2nm after testing.

Embodiment 2

[0023] Flaxseed self-emulsifying powder formulation: 8.0% by weight of linseed oil, 4.0% by weight of flax lignans, 4.5% by weight of vitamin C, 4.0% by weight of xylitol, 5.0% by weight of polyoxyethylene hydrogenated castor oil, and 8.0% by weight of n-butanol % by weight, ethylparaben 2.0% by weight and sorbitol 64.5% by weight.

[0024] Preparation steps: heat and mix polyoxyethylene hydrogenated castor oil and n-butanol at 40°C, then add linseed oil, linseed lignan, xylitol, vitamin C, and ethyl p-hydroxybenzoate, stir and mix evenly, Cool to room temperature to form a concentrated oil emulsion, then add sorbitol and mix to form a powder. The powder was completely dispersed in 500ml of water at 37°C until it became a uniform and clear liquid, and the particle size of the microemulsion was 26.7nm after testing.

Embodiment 3

[0026] Flaxseed self-emulsifying powder formulation: linseed oil 18.0% by weight, flax lignans 3.6% by weight, vitamin C 1.8% by weight, xylitol 2.6% by weight, Tween 80 6.4% by weight, lecithin 3.6% by weight, PEG400 12.0% by weight, 1.2% by weight of butylparaben, 25.0% by weight of sucrose and 25.8% by weight of mannitol.

[0027] Preparation steps: heat and mix Tween 80, lecithin, and PEG400 at 30°C, then add linseed oil, linseed lignan, xylitol, vitamin C, and butyl p-hydroxybenzoate, stir and mix evenly, and cool to At room temperature, it forms a concentrated oil emulsion, then adds sucrose and mannitol, mixes to form a powder, and obtains it. The powder was completely dispersed in 500ml of water at 37°C until it became a uniform and clear liquid, and the particle size of the microemulsion was 26.5nm after testing.

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Abstract

The invention relates to a flaxseed preparation for removing toxin, improving effect and resisting oxidization and a preparation method therefor. A flaxseed self-emulsifying composition includes a flaxseed extract, vitamin C, xylitol, an emulsifier, a processing aid and a preservative, wherein the flaxseed extract is flaxseed oil and flax lignans. The self-emulsifying composition can be further processed into a powder by adding a pharmaceutically acceptable excipient. The flaxseed preparation significantly improves anti-oxidizing capability, is high in bioavailability, has simple preparation method, is prepared from easy-to-obtained raw materials, and has good stability.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a detoxification-improving and anti-oxidation linseed preparation and a preparation method thereof. Background technique [0002] With the advancement and development of science and technology, people's pace of life is accelerating day by day. Many people in the fierce competition experience nervousness, irritability, depression, headache, fatigue, memory loss, insomnia, dreaminess, loss of appetite, Symptoms such as dry skin, but there was no abnormality through physical signs and laboratory tests. In the middle state of non-health and non-disease, it is also called sub-health. There are many reasons for sub-health. Excessive tension and pressure, bad lifestyle and habits, adverse effects of environmental pollution, bad mental and psychological stimulation, etc. can all lead to the occurrence of sub-health. The harm caused by sub-health cannot be ignored. Most diseases suc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/55A61K9/14A61K47/26A61P37/04A61P39/06A61K31/375A61K31/047A61K31/7034
CPCA61K9/145A61K31/047A61K31/375A61K31/7034A61K36/55A61K2300/00
Inventor 莫小干任国蓝
Owner 江西樟树市正康医药生物科技有限公司