Thin-layer chromatographic detection method of curcuma zedoary in Fushengkang tablet

A technique of thin-layer chromatography and detection method, which is applied in the field of thin-layer chromatography detection of Fushengkang Tablets, can solve the problems of high filtration difficulty, poor repeatability, easy gelatinization of ether, etc., and achieves reduction of potential harm and color development Accurate results and consistent results
CN107328890AInactive Publication Date: 2017-11-07青岛华仁太医药业有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
青岛华仁太医药业有限公司
Publication Date
2017-11-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a thin-layer chromatographic detection method of curcuma in Fushengkang tablets. This method uses ethyl acetate to extract the volatile oil in Fushengkang as the test solution; and uses the same method to process the reference medicinal material Curcuma to make a reference medicinal solution; petroleum ether (60-90°C)-ethyl acetate-glacial acetic acid is used as Developing agent, use silica gel thin-layer plate to develop, spray with newly prepared vanillin test solution, heat at 105°C until the spots are clear in color; If there are no spots, it means that the finished product of Fushengkang contains zedoary ingredients; and if the chromatogram of the test product does not show the main spot of the same color at the position corresponding to the chromatogram of the reference medicinal material, it means that the finished product of Fushengkang does not contain zedoary ingredients. The present invention uses ethyl acetate to reflux heat the sample instead of using ether to sonicate the sample, which solves the problems of sample gelatinization, adhesion, and difficult filtration, and reduces the potential harm to human health; the color development result is accurate: the spots are clear and reproducible Good performance and high accuracy.
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Description

technical field

[0001] The invention belongs to the technical field of drug detection, in particular to a thin-layer chromatography detection method of curcuma in Fushengkang tablets. Background technique

[0002] Fushengkang Tablets are made from the combination of Pukuizi, Xishuguo, Curcuma, Bupleurum, Gynostemma, Shiitake Mushroom, Astragalus and Licorice. Curative effect, curative effect of chemotherapy, and can enhance the immune function of the body and improve the clinical symptoms of patients with liver cancer. As an oral preparation of anti-cancer traditional Chinese medicine, Fushengkang is a pure traditional Chinese medicine anti-malignant drug exclusively produced in the country. It should have a quality detection method with good reproducibility and strong specificity.

[0003] The traditional Chinese medicine Curcuma is the dried rhizomes of Zingiberaceae plants, Curcuma Curcumae, Curcuma Curcumae, and Curcuma Curcuma. It was first published in "Medicinal Prop...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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