A flocculation and impurity removal process of Scutellaria baicalensis extract and its application

Abstract

The invention provides a flocculation impurity removing process for scutellaria baicalensis extracting solution. According to the flocculation impurity removing process, through the comprehensive application of a flocculant aid and a flocculant, the colloid system in the aqueous extracted solution is destroyed, impurities are removed in advance, thus the hydrolysis of active ingredients is reduced, meanwhile, the clarity of the extracted solution is effectively improved, and therefore, the content of the active ingredients of the scutellaria baicalensis extract and the yield of baicalin are effectively improved. The flocculation impurity removing process comprises the following specific steps: (1) adding a flocculant aid suspension into the scutellaria baicalensis extracting solution, and carrying out uniform stirring to obtain a solution I; (2) heating the solution I, adding a flocculant solution into the solution I, and carrying out uniform stirring to obtain a solution II; (3) adjusting the pH of the solution II to be 4.5-7.0, and carrying out heat preservation and standing treatment; and (4) taking the supernatant obtained after standing of the solution in step (3), carrying out filtering, and carrying out heating for acid adjustment, thus obtaining baicalin precipitate.

Description

technical field [0001] The invention belongs to the technical field of natural product extraction, and in particular relates to a flocculation and impurity removal process for extracting liquid of Scutellaria baicalensis and an application thereof. Background technique [0002] Scutellaria baicalensis is the dried root of the plant Scutellaria baicalensis Georgi, which has the functions of clearing away heat, detoxifying, hemostasis, and preventing miscarriage. It also has strong antioxidant and antitumor effects. The main active ingredient is baicalin. [0003] At present, the Scutellaria baicalensis extract and baicalin used in traditional Chinese medicine preparations and cosmetics are all extracted from Scutellaria baicalensis, and the content of baicalin is used as the main technical index. Scutellaria baicalensis extraction methods include water extraction acid precipitation method, ultrasonic method, ultrafiltration method, alcohol extraction acid precipitation method...

AI Technical Summary

Problems solved by technology

[0005] Some of the above flocculation and sedimentation methods are complicated in process and high in cost, and some of them have unsatisfactory effects, and it is difficult to obtain a transparent supernatant, or the alum is fluffy and difficult to filter, and a large amount of useful solution is entrained in the mud, resulting in a low extraction rate.

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