13results about How to "Reduce hydrolysis" patented technology

This invention relates to the field of skincare technology, disclosing a composition containing acetylated curcumin, its preparation method, and its application. The composition comprises 0.01-0.50 wt% acetylated curcumin, 0.10-0.5 wt% ferulic acid, 0.05-0.40 wt% citric acid compounds, and 5.00-20.00 wt% polyol. Ferulic acid quenches reactive oxygen species and improves the stability of acetylated curcumin; citric acid compounds stabilize the pH of the system, chelate metal ions, block the Fenton reaction, and inhibit the generation of •OH free radicals; the polyol enhances the water solubility of acetylated curcumin and improves the stability of ferulic acid. This invention, through the compounding of ferulic acid, citric acid compounds, and polyol, significantly reduces the problems of discoloration, off-flavor, and pH decrease caused by the decomposition of acetylated curcumin aqueous solutions under high temperature or light conditions. Furthermore, the preparation process is simple, easy to operate, and highly adaptable to various processes.

A system and method for separating aluminum trichloride from cold-hydrogenated silicon tetrachloride includes a pressure-reducing tank, a condenser, a first extraction tank, a second extraction tank, a clear liquid filter, and a clear liquid tank. The system is characterized by: a silicon tetrachloride inlet pipe at the top of the pressure-reducing tank; the bottom of the pressure-reducing tank being connected to the first and second extraction tanks via pipes; the bottoms of the first and second extraction tanks being connected to a dryer via pipes; the side walls of the first and second extraction tanks being connected to the clear liquid filter via pipes; the tops of the first and second extraction tanks being connected to the condenser via pipes; the bottom of the condenser having a liquid outlet pipe connected to the top of the clear liquid tank; and the bottom of the clear liquid tank having a silicon tetrachloride recovery pipe; and the clear liquid filter being connected to the liquid outlet pipe via a pipe. This invention improves the clogging situation of the entire cold hydrogenation system, solves the problem of long-term operation of the cold hydrogenation system, and reduces the equipment failure rate.

This invention relates to a water purification agent with post-adjusted basicity, its preparation method, and its application, belonging to the field of water purification agent technology. The invention provides a method for preparing a water purification agent with post-adjusted basicity, the specific steps of which are: adding a regulator to a water purification agent to obtain a water purification agent with post-adjusted basicity; wherein the water purification agent is an iron salt solution, specifically FeCl3 solution, and the regulator is aluminum citrate solution; or the water purification agent is an aluminum salt solution, and the regulator is at least one of an organic acid and dilute hydrochloric acid. This invention, through the method of post-adjusting basicity, changes the basicity of the water purification agent system, thereby improving the utilization rate of the water purification agent. The prepared water purification agent with post-adjusted basicity ensures water quality treatment effect and stability, and reduces the dosage, thereby reducing the cost of the reagent. In high-alkalinity water bodies, the hydrolysis rate decreases by 50%, and the reagent utilization rate increases to 88%.

The application belongs to the field of pharmaceutical preparations and discloses a soothing pharmaceutical preparation and a preparation method thereof. The preparation method comprises the following steps: firstly, preparing synthetic naphazoline hydrochloride by using compound 1 containing a cyano group, wherein a composite solvent composed of toluene and ethyl acetate is used for condensation reaction in the synthesis process, and dilute hydrochloric acid is used for salt formation; secondly, preparing synthetic pheniramine maleate by using compound 2 containing a halogen group and compound 3 containing a cyano group, wherein a weak base catalyst is used for condensation reaction in the synthesis process; finally, adding functional additives, naphazoline hydrochloride and pheniramine maleate into water, stirring and dissolving, and filling to obtain the soothing pharmaceutical preparation, wherein the pH of the soothing pharmaceutical preparation is 5.7-6.3. The soothing pharmaceutical preparation prepared by the above method can effectively avoid the adverse influence of impurities in naphazoline hydrochloride and pheniramine maleate on the soothing effect.

The invention belongs to the technical field of organic fertilizers, and particularly relates to a compound fertilizer for promoting flower growth and a preparation method thereof. The compound fertilizer for promoting flower growth comprises the following components: an organic matter, a nitrogen fertilizer, a phosphate fertilizer, a synergist and an anti-caking agent, the overall caking rate is low, after the compound fertilizer is compounded with an organic fertilizer, fertilization is performed in the flower growth period, sufficient nitrogen supply promotes functional leaf extension and chlorophyll synthesis, the photosynthetic efficiency is improved, and a continuous assimilation substance source is provided for underground rhizomes and overground branches. The plant is more robust, and the commodity character is obviously improved.

The application discloses a synthesis method of a thiophene pyrimidine derivative, and the method comprises the following steps: in the presence of aluminum chloride and a first solvent, a compound 2 is reacted with N-methyl indole to generate a compound 3; in the presence of a second solvent and methane sulfonic acid, the compound 3 is reacted with 4-fluoro-2-methoxy-5-nitroaniline to generate a compound 4; in the presence of a third solvent and a first base, the compound 4 is reacted with N,N,N'-trimethylethylenediamine to generate a compound 5; in the presence of a fourth solvent and anhydrous potassium carbonate, the compound 5 is reacted with sodium hydrosulfite; then in the presence of a fifth solvent and an acid, a compound 6 is generated; in a sixth solvent, the compound 6 is reacted with 3-chloropropionyl chloride to generate a compound 7; then the compound 7 is reacted with a third base to generate a compound 8; and in a seventh solvent, the compound 8 is reacted with methane sulfonic acid to generate a compound 1. The application further discloses application of the method in preparation of a medicine for treating diseases caused by abnormal cell proliferation caused by overexpression of EGFR and the like.

The invention discloses a preparation method of a coordination polymer containing CuII and research on the inhibition effect of the coordination polymer on soil urease and nitrifying bacteria, and relates to the technical field of fertilizer.The preparation method comprises the steps that 3-aminopyridine and fumaric acid serve as raw materials to synthesize N1, N4-bis (3-pyridyl)-2-butenamide, then CuCl2. 2H2O and the synthesized N1, N4-bis (3-pyridyl)-2-butenamide are used for preparing the coordination polymer containing CuII. The novel coordination polymer [Cu (3-bbpa) (5-HIPA). H2O] is synthesized from N, N, N, N ', N'-bis (3-pyridyl)-2-butenamide and 5-hydroxyisophthalic acid by a hydrothermal method, and the crystal structure of the novel coordination polymer [Cu (3-bbpa) (5-HIPA). H2O] is analyzed to research the influence of the novel coordination polymer as an inhibitor on soil urease and nitrifying bacteria. The difunctional inhibitor is studied to delay the conversion process of urea from urea nitrogen to ammonium nitrogen and ammonium nitrogen to nitrate nitrogen, overcomes the defect of single inhibition capability of a traditional inhibitor, is strong in inhibition capability, low in toxicity, low in cost and simple in synthesis method, can effectively improve the utilization rate and stability of the fertilizer urea, and has a wide application prospect. Nitrogen loss in agricultural activities is reduced, the fertilization cost is reduced, and the grain yield is increased.

The application belongs to the technical field of high polymer materials, and particularly relates to a PET-based long-acting antistatic master batch as well as a preparation method and application thereof. The application adopts HBP-IM and HOOC-PEG-COOH as comonomers, and anchors the antistatic active chain segment to the PET main chain through in-situ polycondensation reaction, so as to avoid the resolution and diffusion loss of the antistatic agent in the subsequent use or washing process. The hyperbranched structure provides sufficient free volume for the imidazole salt ion group, and cooperates with the effective passivation of trimethyl phosphate on the catalyst activity and the end capping of the carbodiimide on the carboxyl group, so as to jointly inhibit the ester exchange side reaction that may be intensified in the polycondensation process. The reaction process is precisely controlled through a stepwise reduced-pressure polycondensation program, the functionalized PET copolymer melt obtained from the polymer kettle is directly pumped into a double-screw extruder for blending and granulation in a molten state without cooling and granulation, and the hydrolysis and thermal cracking probability of the PET molecular chain in the secondary heating process is greatly reduced.

The present application belongs to the technical field of polycarbonate recycling, and relates to a regenerated transparent polycarbonate material and a preparation method thereof. The material comprises the following components in parts by weight: 95.5-99.87 parts of waste polycarbonate chips, 0.1-0.5 parts of an antioxidant compound, 0.01-3.0 parts of a chain extender, and 0.01-0.5 parts of a lubricant. The preparation method comprises the following steps: (1) drying; (2) mixing; and (3) melt granulation. The regenerated transparent polycarbonate material obtained by the present application has excellent mechanical properties and color stability, and is more likely to replace the application of virgin polycarbonate materials, thereby achieving effective recycling and utilization of waste transparent polycarbonate products.

The invention discloses a preparation method of a CoCrFeNiCuPrx high-entropy alloy based on H3Pr, and relates to a CoCrFeNiCuPrx high-entropy alloy. The H3Pr powder and the high-entropy alloy are prepared through a direct hydrogenation method and a powder metallurgy method respectively, and Co, Cr, Fe, Ni and Cu elementary substance powder and intermediate hydride H3Pr powder are weighed according to the proportion; and after high-energy mechanical ball milling, the powder is pressed and molded into a small round ingot, and the small round ingot is sintered through a vacuum rapid hot pressing sintering process, so that all elements are fully diffused. According to the preparation method disclosed by the invention, the CoCrFeNiCuPrx high-entropy alloy is prepared on the basis of H3Pr; the problems that the strength and hardness of the CoCrFeNiCu high-entropy alloy are low and the strength and hardness of the CoCrFeNiCu high-entropy alloy are not obviously improved by elemental Pr are solved, the decomposition temperature of H3Pr during heating is lower than the melting point of metal Pr, released Pr atoms can enter surrounding high-entropy alloy matrix crystal lattices only through short-distance diffusion, segregation of matrix elements and the oxidation tendency of Pr are greatly relieved, and the strength and hardness of the CoCrFeNiCu high-entropy alloy is improved. And a microstructure with relatively uniform components is obtained.

The application discloses a preparation method and application of a Co-based spinel material for catalyzing low-temperature regeneration of a rich-amine solution, and the Co-based spinel material is prepared by the following steps: taking anhydrous oxalic acid solution as a coprecipitator, forming a precipitate from (CH3COO)2Co·4H2O and acetate dissolved in H2O and C2H5OH, and aging the precipitate under stirring for 12 hours to form a transition metal doped Co-based composite metal oxide; taking an ammonia solution to provide an alkaline environment to promote hydrolysis of tetrabutyl titanate and perform outer dynamic coating of a TiO2 core-shell structure; and taking a sulfuric acid solution to impregnate to anchor graft an acidification group and form a sulfuric acid acidification core-shell structure Co-based spinel. The prepared catalyst has excellent catalytic activity for low-temperature intensified regeneration of a rich-amine solution.

The present invention relates to poly(pentafluorophenyl ester)-based polymers for manufacturing electrochemical sensors, wherein the polymers have high reactivity with amine functional groups, cause less hydrolysis, maintain good solubility in organic solvents for general purposes, and have less steric hindrance and toxicity or side effects compared to polymers having similar structures, and thus are useful in insertion-type devices, especially continuous glucose monitoring systems whose part is inserted into the human body.

The invention relates to the field of medicinal chemistry, in particular to a synthesis process of a 2-TBS adenosine phosphoramidite monomer. Comprising the following steps: S1, carrying out silylation protection on 2 ', 3' and 5 'hydroxyl groups of adenosine to obtain a compound A; s2, reacting the compound A with benzoyl chloride to obtain a compound B; s3, carrying out selective deprotection on the compound B and a hydrogen fluoride-pyridine complex to obtain a compound C; s4, reacting the compound C with 4, 4 '-dimethoxytriphenylmethyl chloride to obtain a compound D; and S5, carrying out phosphorylation reaction on the compound D and a phosphorus reagent to obtain a compound E. According to the method, the problems that the total yield of the 2-TBS adenosine phosphoramidite monomer is low, and the stability and the purity of an intermediate product are poor are effectively solved, through a high-selectivity reaction system, the synthesized target product has high selectivity, the yield and the purity are improved, and the separation and purification steps are simplified by stabilizing groups of the intermediate product.