The invention relates to a system for producing 2,3,5,6-4-methoxymethyl-tetrafluorobenzyl alcohol, which comprises a toluene material storage tank, a dimethyl sulfate material storage tank, a diol-alkali aqueous solution storage tank, a first heat exchanger, a mixer, a microchannel reactor, a first-stage layering tank group, a second-stage layering tank group, a washing mixer, a post-washing reaction liquid receiving tank, a second heat exchanger, a continuous desolventizer, a methylbenzene recovery tank, and a final product tank. A preparation process includes the following steps: a diol-alkali aqueous solution is prepared for later use; the diol-alkali aqueous solution is heated, dimethyl sulfate and toluene are mixed and heated, the diol-alkali aqueous solution and the dimethyl sulfate-toluene solution simultaneously enter the reactor and are mixed to react, reaction liquid undergoes layering and washing treatment, the washed reaction liquid is distilled to recover the toluene, and thereby crude benzyl alcohol is obtained. Continuous production is realized, the reaction rate is higher than the conventional reaction rate, the reaction time is short, the efficiency of production is high, the production of the byproduct diether is reduced, production yield is increased, and consumption in production is reduced.