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Anti-inflammatory cough lozenge pharmaceutical composition and preparation method thereof

A technology of anti-inflammatory cough tablets and compositions, applied in the field of traditional Chinese medicine compositions, which can solve the problems of high toxicity of ephedrine and achieve the effects of complete extraction, improved quality of the original drug, and low temperature

Inactive Publication Date: 2017-11-17
JILIN AODONG GROUP DALIAN PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, ephedrine in ephedra is highly toxic, especially cardiotoxicity, and a small dose can cause poisoning

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 A pharmaceutical composition for anti-inflammatory and cough-relieving tablets, comprising the following raw materials in parts by weight: 120 cotyledon leaves, 130 platycodon, 180 Radix Pseudostellariae, 90 centipede, 11 poppy shells, 35 daphnia japonica, 15 perilla seeds, Vitex 110, Ginseng 25, Andrographis 110, Honey Lily 60, Ume 35.

[0015] Soak Pseudostellariae Pseudostellaria, Platycodon grandiflorum, and Baibu with 8 times of water for 3 hours, then extract the medicinal materials together with the infiltration solution continuously and dynamically for 2.5 hours, and filter the extract for use; Dynamic countercurrent extraction for 2.5 hours, the extract was filtered and combined with the above filtrate, passed through a resin adsorption column with divinylbenzene as a crosslinking agent, toluene, xylene, etc. 45-55% ethanol for elution, the ethanol eluate is distilled to recover ethanol and then combined with the above-mentioned medicinal solution, co...

Embodiment 2

[0017] 160 cotyledon leaves, 160 bellflowers, 240 heterophylla, 130 centifolia, 14 poppy shells, 65 sunflowers, 45 perilla seeds, 160 yellow vitex seeds, 45 Nansha ginseng, 160 Andrographis paniculata, 100 honey lilies, and 60 black plums. The preparation method is the same as in Example 1.

Embodiment 3

[0019] 130 cotyledon leaves, 140 platycodon platycodon, 200 ginseng heterophylla, 100 centipeda, 12 poppy shells, 40 datura flowers, 25 perilla seeds, 130 vitex seeds, 30 nansha ginseng, 120 Andrographis paniculata, 75 honey lilies, 40 black plums. The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention provides an anti-inflammatory cough lozenge pharmaceutical composition. The anti-inflammatory cough lozenge pharmaceutical composition comprises the following raw materials of thorny elaeagnus leaf, platycodon grandiflorum, radix pseudostellariae, radix stemonae, pericarpium papaveris, flos daturae, perillaseed, negundo chastetree fruit, ladybell root, andrographis paniculata, honey lily and fructus mume. According to the anti-inflammatory cough lozenge pharmaceutical composition, the flos daturae is used for relieving cough and asthma, the perillaseed is used for lowering the adverse flow of qi to relieve the asthma, and the two medicines are used together and can replace ephedra in a prescription. Cough lozenge has the functions of being capable of diminishing inflammation, relieving the cough, reducing phlegm and stopping the asthma, is good in treatment effect and has no toxic and side effect. The anti-inflammatory cough lozenge pharmaceutical composition is prepared by applying the advanced techniques of dynamic countercurrent extraction, macroreticular adsorption, microwave sterilization and the like, and the quality of medicine is ensured.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medicinal composition of anti-inflammatory and cough-relieving tablets and a preparation method thereof. Background technique [0002] Cough is one of the most common symptoms in the respiratory system. It is a protective measure of the human body and is beneficial to the body. When the respiratory mucosa is stimulated by foreign bodies, inflammation, secretions or allergic factors, it will be caused reflexively. Cough helps to eliminate foreign bodies or secretions that invade the respiratory tract from the outside and eliminate respiratory irritation factors. Mild cough can remove sputum and foreign bodies in the trachea, and can be relieved naturally. Generally, it is not necessary to take cough medicine; strong and frequent cough, especially dry cough, may aggravate the condition and cause complications. Use cough medicine. There are many folk prescriptions fo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/28A61P11/14A61P29/00
CPCA61K9/2027A61K9/2806A61K36/185A61K36/19A61K36/342A61K36/346A61K36/36A61K36/535A61K36/66A61K36/736A61K36/81A61K36/85A61K36/8967A61K36/904A61K2236/331A61K2236/51A61K2236/55A61K2300/00
Inventor 刘德胜张春雷
Owner JILIN AODONG GROUP DALIAN PHARMACEUTICAL CO LTD