Preparation method of tumor targeted photothermal therapy nanocarrier and application
A photothermal therapy and tumor targeting technology, which is applied in the field of preparation of nanocarriers for tumor-targeted photothermal therapy, can solve the problems of normal cell damage, patient trauma and complications, and achieves good photothermal therapy effect and good photothermal therapy. Transfer characteristics, mild effects
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0040] A method for preparing a tumor-targeted photothermal therapy nanocarrier, comprising the following steps:
[0041] S1. Preparation of GO-MoS 2 Composite: get ammonium molybdate 0.265g, sodium sulfide 1.152g, dissolve in 25ml water respectively, obtain ammonium molybdate and sodium sulfide solution; get 2.5ml (mass concentration is 1%) graphene oxide sol, dilute to 100ml, GO solution was obtained; the ammonium molybdate solution was added to the GO solution, magnetically stirred for 30 minutes, then the sodium sulfide solution was slowly added, and 10ml of 5mol / L hydrochloric acid was added dropwise, and the reaction was carried out for 1 hour;
[0042] S2. Then add 2 g of L-cysteine to the reaction solution, adjust the pH to 4.5, put it into a hydrothermal kettle and react at 200° C. for 24 hours;
[0043] S3, after the reaction solution is cooled, centrifuge and wash at 3500 rpm for 5 min (repeat 6 times), discard the supernatant; obtain sample A;
[0044] S4. Modi...
Embodiment 2
[0049] Repeat Example 1, the only difference is: in the preparation of GO-MoS 2 In the compound process, adjust the addition of sodium sulfide to 0.58g or 2.30g, and the rest of the steps are the same as in Example 1, and MoS can be obtained 2 Samples with different loading ratios.
Embodiment 3
[0051] Repeat Example 1, the only difference is: in the preparation of GO-MoS 2 In the composite process, the graphene oxide powder obtained by the modified Hammers method is used instead of the graphene oxide sol, and the rest of the steps are the same as in Example 1, and GO-MoS can also be prepared 2 The complex can be used to compare the effect of different raw materials on the cytotoxicity of the vector.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com