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Embedding type sunscreen cream and preparation method thereof

A kind of sunscreen and embedding technology, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve the problems of low light resistance and light stability, achieve good drug release, reduce irritation, reduce Effects of Drug Leakage

Active Publication Date: 2018-01-09
上海格兰化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the state of pure compound, octyl methoxycinnamate has high photostability, but in the emulsification system of sunscreen cosmetics, especially in the presence of water and surfactants, its light resistance under ultraviolet light or low photostability

Method used

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  • Embedding type sunscreen cream and preparation method thereof
  • Embedding type sunscreen cream and preparation method thereof
  • Embedding type sunscreen cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1: as figure 1 As shown, an embedded sunscreen, each component and its corresponding weight percentage are shown in Table 1, and are prepared through the following steps:

[0045] Step 1: Mix solid lipid and emulsifier, heat at constant temperature to 85-90°C, then add sunscreen and mix evenly to form lipid phase;

[0046] Step 2, mixing polysorbate-80, pentylene glycol, lecithin, and water and heating at a constant temperature to 85-90°C to form a water phase;

[0047] Step 3, adding the lipid phase into the water phase and mixing evenly, keeping the temperature at 85-90°C to form a mixed phase;

[0048] Step 4, put the mixed phase into a high-pressure homogenizer for pre-emulsification at a speed of 8000 rpm for 3 minutes to form a mixed phase emulsion;

[0049] Step 5: pressurize the high-pressure homogenizer to 600 bar, and cycle 3 times to obtain embedded sunscreen.

[0050] Wherein, the sunscreen agent comprises octyl methoxycinnamate, octocrylene, b...

Embodiment 2-10

[0051]Example 2-10: An embedded sunscreen, the difference from Example 1 is that each component and its corresponding weight percentage are shown in Table 1.

[0052] Each component and weight percent thereof in table 1 embodiment 1-10

[0053]

[0054]

Embodiment 11-20

[0055] Examples 11-20: An embedded sunscreen, the difference from Example 1 is that each component and its corresponding weight percentage are shown in Table 2.

[0056] Each component and weight percent thereof in table 2 embodiment 11-20

[0057]

[0058]

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Abstract

The invention discloses an embedding type sunscreen cream and a preparation method thereof, and relates to the technical field of cosmetics. The embedding type sunscreen cream is prepared from the following components in percentage by weight: 14 to 20% of solid lipid, 4.5 to 6% of emulsifier, 8 to 14% of sunscreen agent, 1 to 3% of polysorbate-80, 0.5 to 1.5% of pentanediol, 0.5 to 1.5% of lecithin, and the balance of water. The embedding type sunscreen cream has the advantages that the solid lipid is used as the raw material to prepare the sunscreen cream embedded with the composite sunscreenagent, so that the embedding rate is high, the medicine carrying amount is high, the stability is high, the irritation property is low, the medicine release property is good, and the like; by compounding three types of sunscreen agents, the good synergistic function on the sunscreen effect is realized, and the SPF (sun protect factor) value and PFA (protection factor of ultraviolet A) value are improved; the particle size is increased by the molecules of the solid lipid, so that the sunscreen agents are stayed at the skin surface to realize the sunscreen function; the periphery of each sunscreen agent is coated with the solid lipid, so that the medicine can be effectively released, the leakage of medicine is reduced, and the irritation to the skin is reduced; the liquid oil grease is notneeded, so that the greasiness is reduced; the organic solvent is not needed, so that the irritation property is decreased.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an embedded sunscreen and a preparation method thereof. Background technique [0002] Nowadays, due to environmental pollution, the atmosphere has been damaged to varying degrees, and the impact of ultraviolet rays on the skin is becoming more and more serious. Skin can be damaged when it is exposed to the sun for a long time without taking any protective measures. The ultraviolet rays contained in sunlight are divided into long-wave ultraviolet rays (UVA) of 320nm to 400nm by the skin science community, medium-wavelength ultraviolet rays (UVB) of 280nm to 320nm, and short-wave ultraviolet rays (UVC) of 200nm to 280nm. Ultraviolet rays below 280nm are absorbed by the ozone layer and cannot reach the ground. The ultraviolet rays reaching the ground will have various effects on people's skin. The UVB can cause erythema or blisters on the skin, promote the formation of melanin, c...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/55A61K8/40A61K8/37A61K8/14A61K8/35A61Q17/04
Inventor 陈宝祺庞振宜潘颀钧冯彩琴
Owner 上海格兰化妆品有限公司
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