Traditional Chinese medicine composition having blood sugar reducing effect and application thereof

The technology of a composition and a diabetes drug is applied in the field of traditional Chinese medicine compositions with hypoglycemic effect, which can solve problems such as large side effects and achieve the effects of small side effects, repairing damaged pancreatic islet cells, and preventing and treating diabetes complications.

Inactive Publication Date: 2018-02-09
HENAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have their own limitations, especially chemical hypoglycemic drugs have side effects such as large side effects

Method used

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  • Traditional Chinese medicine composition having blood sugar reducing effect and application thereof
  • Traditional Chinese medicine composition having blood sugar reducing effect and application thereof
  • Traditional Chinese medicine composition having blood sugar reducing effect and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1: the preparation of hypoglycemic traditional Chinese medicine composition granule

[0019] (1) The proportioning of each raw material is as follows: 30 parts of astragalus, 25 parts of raspberry, 15 parts of salvia miltiorrhiza, 12 parts of yam, 10 parts of angelica, and 8 parts of taurine.

[0020] (2) Crush raspberry and yam into fine powder, pass through a 60-mesh sieve; mix astragalus, salvia miltiorrhiza, and angelica, and decoct 3 times with water, each time for 1 to 2 hours, combine the decoction liquid, filter, and concentrate the filtrate to the relative The density is 1.20, cooled to room temperature, adding an equal volume of ethanol, standing, filtering, concentrating the supernatant into a thick paste for later use, and recovering the ethanol; adding raspberry and yam crushed fine powder, taurine, starch to the above thick paste , dextrin, and glucose are evenly stirred to obtain a soft material with suitable elasticity and moderate hardness, e...

Embodiment 2

[0021] Embodiment 2: the preparation of hypoglycemic traditional Chinese medicine composition capsule:

[0022] (1) The following raw materials are prepared in parts by weight: 30 parts of astragalus, 25 parts of raspberry, 15 parts of salvia miltiorrhiza, 12 parts of yam, 10 parts of angelica, and 8 parts of taurine.

[0023] (2) Decoct astragalus, raspberry, salvia miltiorrhiza, yam, and angelica with water for 3 times, each time for 1-2 hours, combine the decoction liquid, filter, concentrate the filtrate, cool to room temperature, add an equal amount of ethanol, and let stand. Filter the supernatant, concentrate to a relative density of 1.2-1.3, recover ethanol, add taurine, starch, dextrin, and glucose, stir evenly, granulate, pack into capsules, and pack. Each capsule is filled with 0.65g of granules, which is equivalent to 8.5g of crude drug content (total weight of astragalus, raspberry, salvia, yam, angelica and taurine).

Embodiment 3

[0024] Embodiment 3: the preparation of hypoglycemic traditional Chinese medicine composition tablet:

[0025] (1) The following raw materials are prepared in parts by weight: 30 parts of astragalus, 25 parts of raspberry, 15 parts of salvia miltiorrhiza, 12 parts of yam, 10 parts of angelica, and 8 parts of taurine.

[0026] (2) Crush raspberry and yam into fine powder, pass through a 60-mesh sieve; decoct astragalus, salvia miltiorrhiza, and angelica with water for 3 times, each time for 1 to 2 hours, combine the decoction liquid, filter, and concentrate the filtrate to a relative density of 1.20, cool to room temperature, add an equal volume of ethanol, let it stand, filter the supernatant, recover the ethanol, concentrate the supernatant into a thick paste for later use; add raspberry and yam crushed fine powder and taurine to the above thick paste , starch, dextrin, and glucose were evenly stirred and granulated, dried at 50-60°C for 5-6 hours, talcum powder, magnesium st...

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Abstract

A traditional Chinese medicine composition having a blood sugar reducing effect includes, by weight parts, 20-50 parts of radix astragali, 10-20 parts of radix salviae miltiorrhizae, 10-30 parts of raspberry, 8-20 parts of yam, 5-15 parts of radix angelicae sinensis and 3-10 parts of taurine. In application of the traditional Chinese medicine composition having the blood sugar reducing effect in preparation of diabetes drugs, and the drugs for treating diabetes are granules, capsules or tablets. In the composition, the radix astragali and the yam benefit qi, strength the spleen and promote thesecretion of saliva or body fluid; the raspberry benefits the liver and the kidney; the radix salviae miltiorrhizae and the radix angelicae sinensis promote circulation and remove stasis; and the taurine reduces blood sugar. The reasonable compatibility of the materials enables various materials to produce a good synergistic effect in terms of efficacy, and the made composition has good effects of reducing blood sugar, repairing damaged islet cells, enhancing activity of insulin and accelerating glucose metabolism, thereby achieving the goal of reducing blood sugar.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition with hypoglycemic effect and application thereof. Background technique [0002] Diabetes mellitus is a chronic comprehensive disease mainly caused by the disorder of glucose metabolism caused by hereditary or acquired insufficient secretion of insulin by the pancreas or insulin resistance. Clinically, hyperglycemia is the main feature. In typical cases, symptoms such as polyuria, polydipsia, polyphagia, and emaciation may appear, that is, symptoms of "three excesses and one deficiency". With the improvement of living standards, the incidence of diabetes is increasing year by year, and it has become the third chronic disease that seriously endangers human health after tumors and cardiovascular and cerebrovascular diseases. Due to the great harm that diabetes has brought to human beings, the World Healt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P3/10A61K31/185
CPCA61K31/185A61K36/232A61K36/481A61K36/537A61K36/73A61K36/8945A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 谢欣梅庞晓斌杨杰张佳琳刘富甲田子夏郭姗姗王乐乐魏召艺
Owner HENAN UNIVERSITY
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