3D printing personalized customization artificial vertebral body and preparation method thereof

A 3D printing and vertebral body technology, applied in the field of spinal vertebral body reconstruction, can solve problems such as complications in the donor area, immune rejection, and slow replacement of allogeneic bone, so as to promote bone tissue ingrowth, enhance mechanical locking, Good long-term fixative effect

Pending Publication Date: 2018-02-16
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, autologous iliac crest transplantation has shortcomings such as insufficient bone mass, complications in the bone donor site, and inability to provide immediate stability. Allogeneic bone transplantation has immune rejection, virus infection, and slow replacement of allogeneic bone, so its clinical application is limited.
For the traditional titanium mesh and titanium alloy artificial vertebral body, the strength is high, but the elastic modulus (110GPa) is much higher than that of natural bone (cortical bone is about 3-12GPa), and there is a problem of metal-bone interface, which will cause stress shielding , leading to bone resorption and implant loosening, collapse, displacement and other complications

Method used

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  • 3D printing personalized customization artificial vertebral body and preparation method thereof
  • 3D printing personalized customization artificial vertebral body and preparation method thereof

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Embodiment Construction

[0019] The present invention will be described in further detail below in conjunction with the accompanying drawings.

[0020] see figure 1 , 2, the present invention comprises the porous spindle type artificial vertebral body that is hollow, the height of both ends is transparent and the distance between the normal vertebral body endplates adjacent to the defective vertebral body is equal, and the porous structure 8 adopts a regular dodecahedron structure or a small bone Beam structure, the diameter of both ends of the vertebral body is 2mm-4mm smaller than the outer diameter of the normal vertebral body endplate adjacent to the diseased vertebra; the diameter of the middle section of the vertebral body is 25%-35% smaller than the endplates at both ends and is connected with the two ends to form a streamline Body, the aperture of the porous spindle-shaped artificial vertebral body is 0.4mm-0.6mm, the wire diameter is 0.25mm-0.4mm, and the porosity is 55%-75%. 2mm upper and l...

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Abstract

The invention discloses a 3D printing personalized customization artificial vertebral body and a preparation method thereof. Pre-operation CT scanning is performed on a coloboma vertebra to build a 3Dmodel, due to the optimized design, a 3D porous bionic personalized spine vertebra is printed, and the biological compatibility is improved due to biological activity processing. Compared with the prior art, the personalized vertebra precisely replaces coloboma, the immediate stability of the artificial vertebra is improved, the vertebra biological compatibility is improved due to activated processing, the vertebra and peripheral bone combining capacity is improved, and long-term stability of the artificial vertebra inside the human body is improved.

Description

technical field [0001] The invention relates to the field of spinal vertebral body reconstruction after total vertebral body resection, and specifically relates to a 3D printing personalized customized artificial vertebral body and a preparation method thereof. Background technique [0002] Vertebral tumors, tuberculosis, fractures and other factors can often lead to serious damage to the vertebral body, resulting in spinal fractures, instability, symptoms of nerve and spinal cord damage, and even paraplegia. Such patients often require surgery to remove the diseased vertebrae to fully decompress the spinal cord, thereby relieving pain and improving neurohormonal function. However, the operation will cause local bone defects, damage the continuity of the spine, and seriously affect the support function and stability of the spine. Therefore, it is very important to restore the continuity of the spine and rebuild the stability of the spine. At present, the incidence of spina...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/44B22F3/105C25D11/26B33Y10/00B33Y80/00
CPCA61F2/44C25D11/026C25D11/26B33Y10/00B33Y80/00A61F2002/30199A61F2002/30092A61F2002/30593A61F2002/30327A61F2002/30985B22F10/00B22F10/38B22F10/62B22F10/36B22F10/28B22F10/362Y02P10/25
Inventor 郭征石磊栗向东付军李小康裴延军吴智钢赵军刚吴杰
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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