Preparation method of biological ink material for 3D printing

A bio-ink and 3D printing technology, applied in the field of 3D printing, can solve the problem of rapid curing molding that is difficult to balance cell compatibility, bioactivity and mechanical properties, cell activity, poor mechanical properties of scaffolds and biocompatibility, and rapid curing molding Difficulties and other problems, to achieve good healing effect, good biocompatibility, good mechanical properties
CN107744602AInactive Publication Date: 2018-03-02GUANGDONG TAIBAO MEDICAL DEVICE TECH RES INST CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGDONG TAIBAO MEDICAL DEVICE TECH RES INST CO LTD
Publication Date
2018-03-02
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The invention discloses a preparation method of a biological ink material for 3D printing. The preparation method mainly comprises preparing modified sodium alginate, and preparing a biological ink material. According to the present invention, the materials used by the preparation method comprise active cells, a cell culture medium, a photoinitiator, modified sodium alginate and antioxidant enzyme; sodium alginate is modified through light curing, such that the modified sodium alginate can retain the original good biocompatibility and the original good hemostasis of the sodium alginate, and can further has double cross-linking property due to the linking of the light-curable group to the molecule chain of the sodium alginate, such that the rapid curing molding can be achieved; the biological material has good biocompatibility with active cells so as to achieve active printing; and the hydrogel formed through the curing molding of the biological ink material has advantages of good mechanical property, healing promoting, bleeding stopping and good biocompatibility.
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Description

technical field

[0001] The invention belongs to the field of 3D printing, and in particular relates to a preparation method of a bio-ink material which can be used for 3D printing. Background technique

[0002] 3D printing technology is a new manufacturing technology that has emerged in recent years. This technology is mainly under the control of a computer, according to the computer-aided design (CAD) model or computer tomography (CT) of the printed object. Accurate 3D stacking, digital molding technology that quickly manufactures 3D objects of specified shape.

[0003] So far, most of the products manufactured by 3D printing technology are used for implanting organs in the body, and there are still great challenges for soft tissue repair, among which the development of biomaterials suitable for 3D printing is the key.

[0004] In the process of soft tissue repair, there are problems such as long healing period and easy scar hyperplasia. Currently, high-end medical dressin...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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