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Composition containing resveratrol and used for treating ulcerative colitis

A technology of ulcerative colitis and resveratrol, applied in the direction of drug combination, effective ingredients of hydroxyl compounds, food ingredients containing natural extracts, etc., can solve the problems of not advocating long-term use, large toxic and side effects, and no control of diseases. To achieve the effect of color coordination and moderate sweet and sour taste

Inactive Publication Date: 2018-04-20
天津药食同源健康产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing therapeutic drugs are 5-aminosalicylic acid, steroid hormones and immunosuppressants, but these therapeutic drugs have the disadvantages of low patient compliance, large toxic and side effects, and uncertain long-term efficacy.
For example, adding hydrocortisone to normal saline enema treatment is inconvenient and patients are unwilling to use it; application of hormone therapy in the acute attack period is valuable, because it has certain side effects, so most do not advocate long-term use; the immunosuppressant thiazole Purines help reduce corticosteroid use in chronic cases but have no disease control role when the disease is exacerbated

Method used

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  • Composition containing resveratrol and used for treating ulcerative colitis
  • Composition containing resveratrol and used for treating ulcerative colitis
  • Composition containing resveratrol and used for treating ulcerative colitis

Examples

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Effect test

Embodiment 1

[0044] Granule containing the composition of the present invention and its preparation method:

[0045] Crush and sieve the prebiotics, and select fine powder under a 60-mesh sieve. Take by weighing 1Kg of resveratrol, 5Kg of grape extract, and 10Kg of prebiotics according to the proportioning ratio. well mixed. Add the mixed fine powder to the binder, the binder is alcohol with a mass concentration of 80%, and the amount of the binder is 4% of the sum of the mass of the remaining components to make 60-mesh granules. Dry under certain conditions, the drying time is 60 minutes, pack separately, and get final product.

Embodiment 2

[0047] Granule containing the composition of the present invention and its preparation method:

[0048] The prebiotics were crushed and sieved, and fine powder was selected through a 80-mesh sieve. Take by weighing resveratrol 5Kg, grape seed extract 10Kg, prebiotic 40Kg according to proportioning. well mixed. Add the mixed fine powder to the binder, the binder is alcohol with a mass concentration of 80%, and the amount of the binder is 3% of the sum of the mass of the remaining components to make 60-mesh granules. Dry under certain conditions, the drying time is 60 minutes, pack separately, and get final product.

Embodiment 3

[0050] Granule containing the composition of the present invention and its preparation method:

[0051] The prebiotics were crushed and sieved, and fine powder was selected through a 80-mesh sieve. Take by weighing 8Kg of resveratrol, 10Kg of grape seed extract, and 40Kg of prebiotics according to the proportioning ratio. well mixed. Add the mixed fine powder to the binder, the binder is alcohol with a mass concentration of 80%, and the amount of the binder is 3% of the sum of the mass of the remaining components to make 60-mesh granules. Dry under certain conditions, the drying time is 60 minutes, pack separately, and get final product.

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Abstract

The invention provides a composition containing resveratrol and used for treating ulcerative colitis. The composition consists of the following components in parts by weight: 1-10 parts of resveratrol, 5-20 parts of a grape seed extract, 10-50 parts of prebiotics and an adhesive which is 2-5% of the total weight of other components, and the binder namely the adhesive is water or an alcohol solution of 80-95%. The components of the composition cooperate for common use, so that the in vivo cell factors can be regulated, and the inflammation can be restrained; and after experiment mice induced with dextran sulfate sodium are intervened with the composition, the symptom of acute colitis is relieved, the weight reduction is restrained, and the colon shrinking degree is obviously improved. The composition preparation is harmonious in color after being brewed and is moderate in mouth feel.

Description

technical field [0001] The invention relates to functional food or health food, in particular to a composition capable of treating ulcerative colitis and its application. Background technique [0002] Ulcerative colitis (Ulcerative colitis, UC) is an inflammatory bowel disease (Inflammatory bowel disease, IBD), characterized by inflammation and ulceration of rectal, colonic mucosa and submucosa. At present, it is believed that the pathogenesis of the disease is the result of the interaction between host response caused by foreign substances, gene and immune influence. Patients with UC will experience clinical symptoms such as periodic diarrhea, abdominal pain, rectal bleeding, blood in the stool, intestinal infection, edema, and ulcers. The course of the disease is long, often lingering and difficult to heal, protracted and repeated, and difficult to cure. In my country, the incidence of ulcerative colitis presents an increasing trend year by year, seriously affecting the ...

Claims

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Application Information

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IPC IPC(8): A23L33/105A23L33/21A61K36/87A61P1/04A61P1/00A61K31/05
CPCA23L33/105A23L33/21A23V2002/00A61K31/05A61K36/87A61K2300/00A23V2200/32A23V2250/21A23V2200/23
Inventor 李赫宇晏仁义范冬辉张东星王磊于滢慧胡丹
Owner 天津药食同源健康产业有限公司
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