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Universal medicinal oil ointment for traumatic injury and preparation method thereof

A technology of wanhua oil and ointment, which is applied in the field of medicine, can solve the problems of high fluidity, increased cost, and inconvenient use, and achieve the effects of reducing surface tension, improving stability, and definite curative effect

Active Publication Date: 2018-10-12
广州白云山敬修堂药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This product is an external preparation. Since the original dosage form is liniment in liquid state, with low viscosity and high fluidity, it stays in the local area for a short time, which not only affects the efficacy of the drug, but also is inconvenient to store, carry, and transport. Disadvantages such as easy to stain clothes
In order to explore the use value of the traditional Chinese patent medicine Dieda Wanhua Oil, by improving the extraction process of the original Chinese medicinal materials and using supercritical carbon dioxide extraction method, the Dieda Wanhua Oil spray and cataplasm have been researched and developed to solve the problem. However, there are also many problems and deficiencies: the stability of Dieda Wanhua Oil Spray is poor, and its microemulsion state is easily destroyed during storage (especially in a lower temperature environment). Destruction leads to stratification, and at the same time, some substances are precipitated to block the nozzle
And its diluent is distilled water, and it is more difficult to evaporate dry in actual use, needs a small amount of repeated use just can reach best effect, and there is inconvenience in use; Some patients have problems such as allergies and itching during actual use. At the same time, it is difficult to use on joints, fingers, etc., and the dosage is not easy to control
Moreover, compared with the original type of liniment and spray, cataplasms need to use more auxiliary materials and packaging materials, and the cost is greatly increased.

Method used

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  • Universal medicinal oil ointment for traumatic injury and preparation method thereof
  • Universal medicinal oil ointment for traumatic injury and preparation method thereof
  • Universal medicinal oil ointment for traumatic injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of embodiment of Dieda Wanhuayou ointment of the present invention, its prescription is composed as follows:

[0029] 1. Medicinal parts:

[0030] Feed according to the following prescription: 288g of wild chrysanthemum, 75g of black medicine, 188g of water wenghua, 75g of Xu Changqing, 150g of garlic, 75g of purslane, 150g of chive, 75g of honeysuckle leaf, 150g of black tiger, 75g of clematis, 75g of kapok skin , Asarum 75g, kudzu flower 138g, sensual grass 75g, stretching tendon rattan 100g, cnidium 75g, iron-clad gold 100g, buckle grass 75g, sumac 100g, rhubarb 75g, mountain angelica 100g, cinnabar root 75g, Guotang 100g snake, 75g Jiujie tea, 100g Dianthus 100g, 75g dianhong, 100g double-faced needle, 75g Zeilan, 100g safflower, 75g Gujingcao, 100g Tutianqi, 138g kapok, 75g duck foot moxa, 75g Fangfeng, 75g of orientalis leaves, 75g of nuxychia, 75g of Dafeng AI, 75g of wintersweet flowers, 50g of Eclipta, 50g of basil, 50g of willow branches, 50g of garden...

Embodiment 2

[0044] A kind of embodiment of Dieda Wanhua oil ointment of the present invention, the prescription proportion of Dieda Wanhua oil ointment of 100g is as shown in Table 2:

[0045] Table 2 Dieda Wanhua Oil Ointment Prescription Ratio

[0046]

Prescription 1

Prescription 2

Prescription 3

Prescription 4

Prescription 5

Prescription 6

Medicinal part A (g)

3.68

3.68

3.68

3.68

3.68

3.68

Medicinal part B(g)

6.32

6.32

6.32

6.32

6.32

6.32

Vaseline (g)

21.60

25.71

27.00

30.40

32.38

34.00

Cetyl alcohol (g)

21.60

20.57

20.25

27.20

25.90

25.50

Isopropyl myristate (g)

10.80

7.71

6.75

13.60

9.71

8.50

Glycerin (g)

34.88

34.88

34.88

16.88

20.08

20.08

Sodium Lauryl Sulfate (g)

0.75

0.80

0.82

1.42

1.51

1.55

Tween-60(g)

0.15

0.10

0.08

0.28

0.19

0.15

Ethylparaben ...

Embodiment 3

[0050] An embodiment of the Dieda Wanhuayou ointment of the present invention, the prescription components and preparation method of the Dieda Wanhuayou ointment are the same as those in Example 1, except that the water phase system is water.

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PUM

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Abstract

The invention discloses universal medicinal oil ointment for traumatic injury. The universal medicinal oil ointment for traumatic injury is prepared from the following components in percentage by mass: 5 to 15 percent of medicinal parts, and the balance of ointment base. Then ointment base is prepared from the following components in percentage by mass: 60 to 80 percent of an oil-phase system, 18.75 to 38.75 percent of a water-phase system, 1 to 2 percent of a surface active agent, and 0.25 percent of ethylparaben. Meanwhile, the invention also discloses a preparation method of the universal medicinal oil ointment for traumatic injury. The ointment provided by the invention has the advantages of durability, convenience in use, stable quality, safety without irritability, lower cost, obvious curative effect, no obvious adverse reaction and the like.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a Dieda Wanhuayou ointment and a preparation method thereof. Background technique [0002] At present, anti-inflammatory and analgesic drugs widely used clinically can be divided into oral dosage forms and external dosage forms. Common external dosage forms include ointments, liniments, sprays and patches. Among these external dosage forms, ointments are relatively convenient to use and carry. Especially in the treatment of bruises, sprains, muscle pain, joint pain, fracture pain and other diseases, the ointment has shown the advantages of being safe, effective, convenient to use and easy to promote clinically. [0003] The Dieda Wanhua Oil involved in the present invention is recorded in the "National Drug Standards of the State Food and Drug Administration", and the standard number is WS 3 -B-3508-98-2016. It is made of 86 Chinese medicinal materials such as Cni...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/06A61P29/00A61K47/06A61K47/10A61K47/14A61K31/045A61K31/125A61K31/618
CPCA61K9/0014A61K9/06A61K31/045A61K31/125A61K31/618A61K36/11A61K36/126A61K36/14A61K36/15A61K36/185A61K36/19A61K36/21A61K36/23A61K36/232A61K36/234A61K36/236A61K36/237A61K36/238A61K36/264A61K36/27A61K36/28A61K36/282A61K36/286A61K36/287A61K36/30A61K36/355A61K36/36A61K36/38A61K36/47A61K36/48A61K36/483A61K36/488A61K36/53A61K36/534A61K36/54A61K36/56A61K36/57A61K36/59A61K36/61A61K36/62A61K36/65A61K36/67A61K36/704A61K36/708A61K36/71A61K36/716A61K36/718A61K36/72A61K36/736A61K36/744A61K36/752A61K36/758A61K36/76A61K36/79A61K36/85A61K36/86A61K36/88A61K36/8884A61K36/8905A61K36/8962A61K36/898A61K36/902A61K36/906A61K36/9062A61K36/9064A61K36/9066A61K36/9068A61K47/06A61K47/10A61K47/14A61K2236/37A61P29/00A61K2300/00
Inventor 陈晓坚江涛彭红英苏锐辉何蓉蓉李怡芳栗原博曾利杰杨滨宾陈丽斯
Owner 广州白云山敬修堂药业股份有限公司