Preparation method of embedded double-layer bletilla striata dressing

An embedded technology of Bletilla striata, applied in the field of biomedicine, can solve the problems of reducing hemostatic effect and wound healing speed, difficult to apply wounds, unfavorable dressings, etc., to achieve efficient hemostasis, antibacterial and healing effects, pure color, The effect of saving resources

Inactive Publication Date: 2018-11-30
WUHAN TEXTILE UNIV
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is not easy to take when used, the surface layer is easy to dissolve, and it is not easy to stick to the wound, which reduces its hemostatic effect and wound healing speed
[0004] The existing Bletilla striata dressing will dissolve and stick because of the blood on the gloves worn by doctors during surgical operations, which is not conducive to the application of the dressing on the wound

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0033] A kind of preparation method of embedded double-layer bletilla striata dressing, described preparation method is carried out according to the following steps:

[0034] a Bletilla striata polysaccharide extraction

[0035] Soak dried bletilla striata stems and distilled water at a mass ratio of 1:3 to 1:10 for 3 to 20 minutes at a temperature of 25 to 40°C, filter through gauze to remove soluble and insoluble impurities , collect the initially cleaned stems of Bletilla striata and dry them in an oven at 30-50°C for 18-24 hours.

[0036] Soak the stems of Bletilla striata after preliminary cleaning and drying with absolute ethanol at a mass ratio of 1:3 to 1:10 for 1 to 3 hours at a soaking temperature of 20 to 30°C, filter through gauze to remove soluble pigments, Collect the stems of Bletilla striata and dry them in an oven at 30-50°C for 18-24 hours.

[0037] Take the depigmented Bletilla striata stem and soak it in distilled water at a mass ratio of 1:3 to 1:10 for ...

Embodiment 1

[0052] a Bletilla striata polysaccharide extraction

[0053] Soak the dried stems of Bletilla striata with distilled water at a mass ratio of 1:3, the soaking time is 3min, the soaking temperature is 25°C, filter through gauze, remove soluble and insoluble impurities, and collect the initially cleaned stems of Bletilla striata Dry in an oven at 30°C for 24h.

[0054] Soak the bletilla striata stems after preliminary cleaning and drying with absolute ethanol at a mass ratio of 1:6, soaking time is 1h, soaking temperature is 30°C, filter through gauze, remove soluble pigments, collect bletilla striata stems and put them in an oven at 50°C Dry for 18h.

[0055] The depigmented Bletilla striata stems were soaked in distilled water at a mass ratio of 1:3 for 3 hours at a soaking temperature of 60°C, filtered through gauze, and the Bletilla striata polysaccharide filtrate was collected.

[0056] Continue the soaking and filtering process of extracting the Bletilla striata polysacc...

Embodiment 2

[0069] a Bletilla striata polysaccharide extraction

[0070] Soak the dried stems of Bletilla striata with distilled water at a mass ratio of 1:5, soak for 10 minutes, soak at 25°C, filter through gauze, remove soluble and insoluble impurities, and collect initially cleaned stems of Bletilla striata Dry in an oven at 30°C for 24h.

[0071] Soak the stems of Bletilla striata after preliminary cleaning and drying with absolute ethanol at a mass ratio of 1:10 for 1 hour, soaking temperature at 30°C, filter through gauze to remove soluble pigments, collect stems of Bletilla striata in an oven at 30°C Dry for 24h.

[0072] The depigmented bletilla striata stems were soaked in distilled water at a mass ratio of 1:10 for 0.5 h at a soaking temperature of 90°C, filtered through gauze, and the bletilla striata polysaccharide filtrate was collected.

[0073] Continue to extract the Bletilla striata polysaccharide filtrate from the Bletilla striata stem block after extracting the Bleti...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a preparation method of embedded double-layer bletilla striata dressing, and belongs to the technical field of biological medicines. The preparation method comprises the following steps: dissolving bletilla striata polysaccharide extracted from bletilla striata tuber in water, thus preparing a casting solution, taking part of the bletilla striata polysaccharide casting solution, carrying out treatment by adopting sodium hydroxide, thus obtaining an embedded-layer casting solution, carrying out directional freezing on the bletilla striata polysaccharide casting solutionfor film forming, carrying out groove carving on the surface of the formed film, pouring the embedded-layer casting solution on the formed film with groove carving under liquid nitrogen refrigeration, thus a double-layer formed film is obtained through refrigeration, and carrying out freeze drying on the double-layer formed film, thus obtaining the embedded double-layer bletilla striata dressing.According to the preparation method provided by the invention, the double-layer bletilla striata dressing is prepared by adopting groove carving and freezing, the combination is reliable, the processis simple, and the problems that during taking for use, the bletilla striata dressing is easily soluble, can adhere to gloves, and has difficulty in separating from the applied wound are solved. Theobtained bletilla striata dressing can be degraded and absorbed in the body, has good compatibility with the living body, and has no side effects to the wound, the directional pore structure guarantees the efficient absorption of the dressing for the penetrating fluid, and meanwhile, the dressing is soft and can not cause injuries to the wound.

Description

technical field [0001] The invention relates to a preparation method of an embedded double-layer bletilla striata dressing, which belongs to the technical field of biomedicine. Background technique [0002] In the clinical use of surgery, the rapid hemostasis of the wound has an important impact on the postoperative recovery of patients. Bletilla striata is a hemostatic material in traditional Chinese medicine, and its tuber extract, Bletilla striata polysaccharide, has excellent hemostasis and strong antibacterial properties, and is a water-soluble substance. Bletilla striata polysaccharide is widely used in the field of wound dressing because of its excellent astringent hemostasis, antibacterial and anti-inflammatory effects, removing putrefaction and promoting muscle growth, and its biological properties are good, biodegradable, and non-toxic and side effects. The existing Bletilla striata dressing is mainly made into a porous structure to improve its water absorption an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/42A61L15/28A61L15/64A61L15/44A61L15/46
CPCA61L15/42A61L15/28A61L15/425A61L15/44A61L15/46A61L15/64A61L2300/232A61L2300/404A61L2300/412A61L2400/04C08L5/00
Inventor 杨红军王晗李美辰翁雅雪张骞陈欣汪林锋庄燕徐卫林
Owner WUHAN TEXTILE UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap