Unlock instant, AI-driven research and patent intelligence for your innovation.

Dendrobium nobile alkaloid eye patch and preparation method thereof

The technology of Dendrobium chinensis and alkaloids is applied in the directions of drug combination, drug delivery, and pharmaceutical formulation, which can solve the problems of high production process requirements and large investment in production equipment, and achieve the effect of relieving eye swelling.

Active Publication Date: 2021-06-18
ZHEJIANG ACAD OF MEDICAL SCI
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the production equipment of this invention has a large investment and high production process requirements, so it is only suitable for pharmaceutical factories and qualified cosmetics enterprises to produce

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Dendrobium nobile alkaloid eye patch and preparation method thereof
  • Dendrobium nobile alkaloid eye patch and preparation method thereof
  • Dendrobium nobile alkaloid eye patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Dendrobium nobile alkaloid eye patch of the present embodiment, its raw material ratio is:

[0050] Raw materials: Dendrobium nobile alkaloids (preparation method: Dendrobium nobile coarse powder plus 10 times the volume and volume percentage of 70% ethanol aqueous solution for reflux extraction for 2 hours, so a total of 2 extractions, the combined filtrate is concentrated under reduced pressure until it has no alcohol smell and then used with quality Dissolve 5% hydrochloric acid aqueous solution, filter with suction, extract the acid aqueous solution 3 times with petroleum ether, basify it with concentrated ammonia water to pH 10.0, extract the alkaline aqueous solution twice with chloroform, concentrate, and dry) 5g, Cassia anthraquinone (Preparation method: add 10 times the volume of cassia seed coarse powder and 80% ethanol aqueous solution to reflux extraction for 2 hours, extract 3 times in total, combine the extracts to concentrate under reduced pressure and dry...

Embodiment 2

[0059] Dendrobium nobile alkaloid eye patch of the present embodiment, its raw material ratio is:

[0060] Raw material: Dendrobium nobile alkaloid 5g, cassia seed anthraquinone 2g, chrysanthemum flavonoid 2g, Budisma flavonoid 2g, lingonberry flavonoid 2g, borneol 1g, taurine 1g and vitamin C 1g.

[0061] Prepare according to the following specific methods:

[0062] (1) Weigh each raw material according to the formula ratio, add an appropriate amount of ethanol to dissolve, and mix well to obtain a raw material mixture solution (A).

[0063] (2) The skeleton material solution is made of the raw materials in the following mass percentages. Take carbomer (4%), hydroxypropyl methylcellulose (8%), polyvinyl alcohol (5%) and distilled water (balance) in Fully swell in a water bath at 50°C, add sodium hyaluronate (1%), laurocapram (1.5%), glycerin (5%), sodium lauryl sulfate (1.5%), methylparaben (0.2%) , sonicated to obtain a framework material solution.

[0064] (3) Add the ra...

Embodiment 3

[0068] Dendrobium nobile alkaloid eye patch of the present embodiment, its raw material ratio is:

[0069] Raw material: Dendrobium nobile alkaloid 5g, cassia seed anthraquinone 2g, chrysanthemum flavonoid 2g, Budisma flavonoid 2g, lingonberry flavonoid 2g, borneol 1g, taurine 1g and vitamin C 1g.

[0070] Prepare according to the following specific methods:

[0071] (1) Weigh each raw material according to the formula ratio, add an appropriate amount of ethanol to dissolve, and mix well to obtain a raw material mixture solution (A).

[0072] (2) The skeleton material solution is made of the raw materials in the following mass percentages, take carbomer (6%), hydroxypropyl methylcellulose (6%), polyvinyl alcohol (5%) and add distilled water (remainder) in Fully swell in a water bath at 50°C, add sodium hyaluronate (1%), laurocapram (1.5%), glycerin (5%), sodium lauryl sulfate (1.5%), methylparaben (0.2%) , sonicated to obtain a framework material solution.

[0073] (3) Add ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
electrical conductivityaaaaaaaaaa
Login to View More

Abstract

The invention discloses a dendrobium alkaloid eye patch with adjustable permeability and a preparation method thereof. The dendrobium alkaloid eye patch is prepared from the following raw materials in weight percentage: 2-10 parts of dendrobium alkaloid, 1-5 parts of cassia anthraquinone, 1-5 parts of chrysanthemum flavonoids, 1-5 parts of bougainvillea flavonoids, 1-5 parts of bilberry flavonoids, 1-5 parts of borneol, 1-3 parts of taurine, vitamin C1-3 share. The preparation method of the dendrobium alkaloid eye patch comprises the following main steps: preparation of raw material solution, preparation of mixed solution of eye patch reservoir, coating, drying, cutting, packaging and the like. The Dendrobium dendrobium alkaloid eye patch polymer skeleton material is composed of carbomer, hydroxypropyl methylcellulose and polyvinyl alcohol. According to the treatment needs of different groups of people, the ratio of the skeleton material is changed to adjust the biological content of the eye patch. According to the release rate of alkali, the Dendrobium alkaloid eye patch with different skin permeability can be obtained.

Description

technical field [0001] The invention relates to the technical field of eye protection patches, in particular to a Dendrobium nobile alkaloid eye patch with an eye protection effect and an adjustable permeability and a preparation method thereof. Background technique [0002] Eyes are the windows of the soul and the most important organ in our human senses. However, with the development of science and technology, modern electronic products such as mobile phones and computers are increasingly inseparable from work and life, and the use of a large number of electronic products will inevitably cause The damage to the eyes is mainly reflected in the visual fatigue of office workers, and the number of myopia is increasing year by year, and it is developing towards a younger age. Chinese people have gradually realized the importance of eye care, and research and development in this field have been paid more and more attention. [0003] The Chinese invention patent application whos...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K9/70A61M37/00A61P27/02A61P25/00A61P29/00A61P1/08A61P27/10A61P27/12A61P27/06A61K31/045A61K31/185A61K31/375
CPCA61K9/0048A61K9/7053A61K31/045A61K31/185A61K31/375A61K36/287A61K36/45A61K36/482A61K36/56A61K36/8984A61M37/00A61P1/08A61P25/00A61P27/02A61P27/06A61P27/10A61P27/12A61P29/00A61K2300/00
Inventor 吴月国陈峰阳赵铮蓉吴蓓丽刘骅张萍
Owner ZHEJIANG ACAD OF MEDICAL SCI