Moschus precious analgesic plaster for treating wind-cold-dampness arthralgia and tendon-vessel spasms and preparation method thereof

Abstract

The invention relates to the field of medical supplies, and particularly relates to a moschus precious analgesic plaster for treating wind-cold-dampness arthralgia and tendon-vessel spasms and a preparation method thereof. The moschus precious analgesic plaster comprises a base cloth layer, an isolation layer, a heating layer and a plaster layer in sequence, wherein the base cloth layer is non-woven cloth; the isolation layer is prepared from polyether wax; the heating layer is used for generating heat when being in contact with air; the plaster layer is a traditional Chinese medicine coatinglayer; and the traditional Chinese medicine coating layer has a coating area more than that of the heating layer, and is used for completely covering the heating layer. According to the moschus precious analgesic plaster, through arranging the heating layer between the isolation layer and the plaster layer, when a temperature is lower, the air can be enabled to be capable of penetrating through the isolation layer through ways of rubbing and the like to accordingly be in contact with the heating layer and release the heat; when the temperature is higher, the isolation layer can block the circulation of the air, so as to inhibit the heat release of the heating layer; the controlled release of the heat is realized; the heating time is prolonged; the precious analgesic plaster is enabled to be more lasting in pharmacodynamic effect, and is more easily absorbed by a human body; and further, the precious analgesic plaster cannot fall off from the skin due to excessive coldness.

Description

technical field

[0001] The invention relates to the field of medical supplies, in particular to a shexiangbaozhen ointment for treating wind-cold-damp arthralgia and tendon spasm and a preparation method thereof. Background technique

[0002] Wind-cold-damp arthralgia, collectively referred to as paralysis of movement, arthralgia of pain, and arthralgia of arrival, is caused by wind, cold, and damp pathogens attacking the meridians, resulting in impeded qi and blood blockage. This disease is commonly seen in rheumatic fever, Rheumatoid arthritis, rheumatoid arthritis, fibrous tissue inflammation and neuralgia etc., tendon spasm refers to limb tendon spasm, the symptom of unfavorable flexion and extension, the complication of this kind of disease is many, and the treatment method in the prior art also There are many, but the effect is often unsatisfactory. This is because the traditional plaster has no thermal effect. After it is applied on the surface of the human body, it d...

Examples

Embodiment 1

[0027] Embodiment 1: the preparation of Baozhen ointment comprises the following steps:

[0028] (1) Polyether wax is coated on the nonwoven fabric at 65°C, and the coating thickness of polyether wax is 3mm;

[0029] (2) Add 50g of acrylonitrile and 100g of polyethylene glycol into deionized water, stir evenly at 70°C, then add 1.5g of cerium ammonium nitrate, react at 40°C for 13h under the protection of argon, and then use deionized Washing with water, drying to obtain poly(acrylonitrile-ethylene glycol) block copolymer;

[0030](3) 20g poly(acrylonitrile-ethylene glycol) block copolymer is dissolved in 200gN, in the N-dimethylacetamide, add 35g tetraethyl ammonium tetrafluoroborate, 0.4g zinc powder and 0.04g gac, Stir evenly to obtain a polymer electrolyte solution;

[0031] (4) Coating the polymer electrolyte solution on the polyether wax, and volatilizing it to dryness under vacuum to obtain a heat generating layer with a thickness of 1 mm;

[0032] (5) Get the parts ...

Embodiment 2

[0033] Embodiment 2: the preparation of Baozhen ointment comprises the following steps:

[0034] (1) Polyether wax is coated on the nonwoven fabric at 75° C., and the coating thickness of polyether wax is 5 mm;

[0035] (2) Add 50g of acrylonitrile and 200g of polyethylene glycol into deionized water, stir evenly at 70-80°C, then add 2.5g of ammonium cerium nitrate, react at 60°C for 8h under the protection of argon, and then use Washing with deionized water, drying to obtain poly(acrylonitrile-ethylene glycol) block copolymer;

[0036] (3) 20g poly(acrylonitrile-ethylene glycol) block copolymer is dissolved in 400gN, in the N-dimethylformamide, add 20g tetraethyl ammonium tetrafluoroborate, 0.2g zinc powder and 0.08g gac, Stir evenly to obtain a polymer electrolyte solution;

[0037] (4) Coating the polymer electrolyte solution on the polyether wax, volatilizing it to dryness under vacuum to obtain a 2mm thick heating layer;

[0038] (5) Get parts by weight and be 2 parts ...

Embodiment 3

[0039] Embodiment 3: the preparation of Baozhen ointment comprises the following steps:

[0040] (1) Coat the polyether wax on the nonwoven fabric at 68° C., and the coating thickness of the polyether wax is 4.5 mm;

[0041] (2) Add 50g of acrylonitrile and 150g of polyethylene glycol into deionized water, stir evenly at 75°C, then add 0.2g of cerium ammonium nitrate, react at 50°C for 10h under the protection of argon, and then use deionized Washing with water, drying to obtain poly(acrylonitrile-ethylene glycol) block copolymer;

[0042] (3) 20g poly(acrylonitrile-ethylene glycol) block copolymer is dissolved in 300gN, in the N-dimethylformamide, add 60g tetraethyl ammonium tetrafluoroborate, 0.6g zinc powder and 0.1g gac, Stir evenly to obtain a polymer electrolyte solution;

[0043] (4) Coating the polymer electrolyte solution on the polyether wax, volatilizing to dry under vacuum to obtain a 3mm thick heating layer;

[0044] (5) Get parts by weight and be 4 parts of mu...

technical field

[0001] The invention relates to the field of medical supplies, in particular to a shexiangbaozhen ointment for treating wind-cold-damp arthralgia and tendon spasm and a preparation method thereof. Background technique

[0002] Wind-cold-damp arthralgia, collectively referred to as paralysis of movement, arthralgia of pain, and arthralgia of arrival, is caused by wind, cold, and damp pathogens attacking the meridians, resulting in impeded qi and blood blockage. This disease is commonly seen in rheumatic fever, Rheumatoid arthritis, rheumatoid arthritis, fibrous tissue inflammation and neuralgia etc., tendon spasm refers to limb tendon spasm, the symptom of unfavorable flexion and extension, the complication of this kind of disease is many, and the treatment method in the prior art also There are many, but the effect is often unsatisfactory. This is because the traditional plaster has no thermal effect. After it is applied on the surface of the human body, it d...

Examples

Embodiment 1

[0027] Embodiment 1: the preparation of Baozhen ointment comprises the following steps:

[0028] (1) Polyether wax is coated on the nonwoven fabric at 65°C, and the coating thickness of polyether wax is 3mm;

[0029] (2) Add 50g of acrylonitrile and 100g of polyethylene glycol into deionized water, stir evenly at 70°C, then add 1.5g of cerium ammonium nitrate, react at 40°C for 13h under the protection of argon, and then use deionized Washing with water, drying to obtain poly(acrylonitrile-ethylene glycol) block copolymer;

[0030](3) 20g poly(acrylonitrile-ethylene glycol) block copolymer is dissolved in 200gN, in the N-dimethylacetamide, add 35g tetraethyl ammonium tetrafluoroborate, 0.4g zinc powder and 0.04g gac, Stir evenly to obtain a polymer electrolyte solution;

[0031] (4) Coating the polymer electrolyte solution on the polyether wax, and volatilizing it to dryness under vacuum to obtain a heat generating layer with a thickness of 1 mm;

[0032] (5) Get the parts ...

Embodiment 2

[0033] Embodiment 2: the preparation of Baozhen ointment comprises the following steps:

[0034] (1) Polyether wax is coated on the nonwoven fabric at 75° C., and the coating thickness of polyether wax is 5 mm;

[0035] (2) Add 50g of acrylonitrile and 200g of polyethylene glycol into deionized water, stir evenly at 70-80°C, then add 2.5g of ammonium cerium nitrate, react at 60°C for 8h under the protection of argon, and then use Washing with deionized water, drying to obtain poly(acrylonitrile-ethylene glycol) block copolymer;

[0036] (3) 20g poly(acrylonitrile-ethylene glycol) block copolymer is dissolved in 400gN, in the N-dimethylformamide, add 20g tetraethyl ammonium tetrafluoroborate, 0.2g zinc powder and 0.08g gac, Stir evenly to obtain a polymer electrolyte solution;

[0037] (4) Coating the polymer electrolyte solution on the polyether wax, volatilizing it to dryness under vacuum to obtain a 2mm thick heating layer;

[0038] (5) Get parts by weight and be 2 parts ...

Embodiment 3

[0039] Embodiment 3: the preparation of Baozhen ointment comprises the following steps:

[0040] (1) Coat the polyether wax on the nonwoven fabric at 68° C., and the coating thickness of the polyether wax is 4.5 mm;

[0041] (2) Add 50g of acrylonitrile and 150g of polyethylene glycol into deionized water, stir evenly at 75°C, then add 0.2g of cerium ammonium nitrate, react at 50°C for 10h under the protection of argon, and then use deionized Washing with water, drying to obtain poly(acrylonitrile-ethylene glycol) block copolymer;

[0042] (3) 20g poly(acrylonitrile-ethylene glycol) block copolymer is dissolved in 300gN, in the N-dimethylformamide, add 60g tetraethyl ammonium tetrafluoroborate, 0.6g zinc powder and 0.1g gac, Stir evenly to obtain a polymer electrolyte solution;

[0043] (4) Coating the polymer electrolyte solution on the polyether wax, volatilizing to dry under vacuum to obtain a 3mm thick heating layer;

[0044] (5) Get parts by weight and be 4 parts of mu...