Composite probiotic buccal tablets capable of preventing and treating oral diseases and preparation method of composite probiotic buccal tablets

A technology for compounding probiotics and oral diseases is applied in the field of compound probiotics lozenges for preventing and treating oral diseases and the preparation field thereof, which can solve the problems of inability to play a health-care role, poor palatability, low nutritional value, etc. The effect of diversified taste and high nutritional value

Inactive Publication Date: 2019-03-29
GUANGDONG YIKEWEI BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Secondly, the types of strains are single, and the taste and function are single
In addition, poor palatability and low nutritional value
It is particularly noteworthy that a large number of studies at home and abroad have shown that due to differences in genetics, living environment, eating habits, etc., the human flora of different ethnic groups is ver

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0020] Example 1

[0021] The method for preparing 100g of composite probiotic lozenges for preventing and treating oral diseases includes the following steps:

[0022] (1) The raw materials are screened and weighed according to the following proportions: 10g of probiotic freeze-dried powder, 50g of prebiotics, 10g of fruit powder, 20g of milk powder, 4g of sugar, 6g of tableted candy additives, of which, tableted candy additives Including 1g of microcrystalline cellulose, 1g of starch sugar, 1g of maltosaccharin, 0.5g of magnesium stearate, 0.5g of citric acid, 1.5g of peppermint, and 0.5g of processing aid silicon dioxide; the probiotic freeze-dried powder is side cheese Lactobacillus CGMCC15025 and Lactobacillus salivarius CGMCC15701, the two probiotics are mixed in any ratio, and the total number of viable probiotics freeze-dried powder is ≥1×10 10 / G;

[0023] (2) Mix the weighed raw materials;

[0024] (3) Compress the mixed raw materials to obtain 100g of composite probiotic l...

Example Embodiment

[0025] Example 2

[0026] The method for preparing 100g of composite probiotic lozenges for preventing and treating oral diseases includes the following steps:

[0027] (1) The raw materials are screened and weighed according to the following proportions: 20g of probiotic lyophilized powder, 30g of prebiotics, 30g of vegetable powder, 10g of milk powder, 5g of sugar, 5g of tableting candy additives, of which, tableting candy additives Including 0.75g of microcrystalline cellulose, 0.75g of starch sugar, 0.75g of maltosaccharin, 0.5g of magnesium stearate, 0.5g of citric acid, 0.25g of Haematococcus pluvialis powder, 1.5g of processing aid silicon dioxide; The probiotic freeze-dried powder is Lactobacillus salivarius CGMCC15701, Lactobacillus paracasei CGMCC15025 and Bifidobacterium longum CGMCC15028, and the ratio of the three is any mixture. The total number of live bacteria of the probiotic freeze-dried powder is ≥1×10 10 / G;

[0028] (2) Mix the weighed raw materials;

[0029] (3)...

Example Embodiment

[0030] Example 3

[0031] The method for preparing 100g of composite probiotic lozenges for preventing and treating oral diseases includes the following steps:

[0032] (1) The raw materials are screened and weighed according to the following proportions: 5g of probiotic freeze-dried powder, 45g of prebiotics, 20g of fruit powder, 15g of milk powder, 3g of sugar, 12g of tableted candy additives, of which, tableted candy additives Including microcrystalline cellulose 1.8g, starch sugar 1.8g, maltosaccharin 1.8g, magnesium stearate 0.9g, citric acid 0.9g, peppermint 1.8g, Haematococcus pluvialis powder 0.6g processing aid silicon dioxide 2.4g The probiotic freeze-dried powder is Lactobacillus salivarius CGMCC15701, Lactobacillus paracasei CGMCC15025, Bifidobacterium longum CGMCC15028 and Lactobacillus rhamnosus CGMCC15027, the ratio of the four is any mixture, the total activity of the probiotic freeze-dried powder Number of bacteria≥1× 10 10 / G;

[0033] (2) Mix the weighed raw mate...

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Abstract

The invention relates to composite probiotic buccal tablets capable of preventing and treating oral diseases and a preparation method of the composite probiotic buccal tablets. The composite probioticbuccal tablets consist of the following components in percentage by mass: 5-20% of probiotic freeze-dried powder, 20-50% of prebiotics, 0-30% of fruit and vegetable powder, 10-40% of milk powder, 3-5% of sugar and an appropriate quantity of tabletting candy additives, wherein the probiotic freeze-dried powder is prepared from one or more of bifidobacterium longum, bifidobacterium animalis subsp.lactis, lactobacillus rhamnosus, lactobacillus plantarum, lactobacillus paracasei and lactobacillus salivarius. A preparation process comprises the steps of (1) screening raw materials for the composite probiotic buccal tablets capable of preventing and treating oral diseases, and performing weighing in proportion; (2) mixing the weighed raw materials; and (3) tabletting the mixed raw materials toobtain the composite probiotic buccal tablets capable of preventing and treating oral diseases. The composite probiotic buccal tablets capable of preventing and treating oral diseases disclosed by the invention are better in the effect of preventing and treating oral diseases, diversified in taste and high in nutrient value.

Description

technical field [0001] The invention relates to the technical field of compound probiotics, in particular to a compound probiotic buccal tablet for preventing and treating oral diseases and a preparation method thereof. Background technique [0002] The human microbial flora forms a symbiont with humans and is considered to be involved in all human growth and development processes. Some even say that the microbial flora is the largest organ of the human body, because the total number of cells in the flora is about several times that of the human body. Among them, oral bacteria There are more than 300 kinds of microorganisms in the group, and the total number reaches more than 10 billion. The beneficial bacteria in the oral cavity of healthy people are dominant. They not only maintain oral health, but also distribute to the intestinal tract and the whole body, and even pass it on to the next generation, producing more effects that are beneficial to health and longevity. Ho...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K9/00A61P1/02A23G3/48A23G3/46A23G3/36A23L33/135A23L33/125A23L33/21A23L33/10A23C9/133A23C9/13A61K35/745
CPCA61P1/02A23C9/13A23C9/1307A23C9/133A23G3/36A23G3/364A23G3/366A23G3/46A23G3/48A23L33/10A23L33/125A23L33/135A23L33/21A61K9/0056A61K35/745A61K35/747A23V2002/00A23V2400/181A23V2400/515A23V2400/175A23V2400/169A23V2400/533A61K2300/00A23V2200/30A23V2250/5116A23V2250/5118A23V2250/28
Inventor 金俞伯金庭飞余保宁葛绍阳
Owner GUANGDONG YIKEWEI BIOLOGICAL TECH CO LTD
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