Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicinal composition for treating constipation, as well as preparation method and application thereof

A technology for treating constipation and a composition is applied in the field of pharmaceutical compositions for treating constipation and their preparation, which can solve the problems of poor resistance of probiotics, decrease in the number of viable bacteria, easy inactivation, etc. Peristalsis, avoid inactivation effect

Active Publication Date: 2019-05-03
尹芳
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the poor resistance of probiotics to low pH values, when taken orally, probiotics are not resistant to gastric acid and are easily inactivated, and the number of viable bacteria will also drop significantly.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicinal composition for treating constipation, as well as preparation method and application thereof
  • Medicinal composition for treating constipation, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A pharmaceutical composition for treating constipation, which is made of the following raw materials in parts by weight: 3 parts of psyllium seed polysaccharide, 8 parts of bee pollen, 2 parts of probiotic agent, 1 part of konjac glucomannan, sodium alginate 1 part, calcium chloride 1 part.

[0022] Wherein, the probiotic bacterial agent is formed by mixing Lactobacillus bulgaricus, Bifidobacterium and Streptococcus thermophilus with a weight ratio of 0.7:0.7:0.5.

[0023] A preparation method of a pharmaceutical composition for treating constipation, comprising the following steps:

[0024] (1) Take sodium alginate, add deionized water at 20°C, stir fully, and configure a sodium alginate solution with a concentration of 0.8%; take konjac glucomannan and add deionized water at 55°C, stir fully, and configure A konjac glucomannan solution with a concentration of 0.6%; the obtained konjac glucomannan solution is mixed with a sodium alginate solution, heated in a water ba...

Embodiment 2

[0028] A pharmaceutical composition for treating constipation, which is made of the following raw materials in parts by weight: 4 parts of plantago polysaccharide, 10 parts of bee pollen, 4 parts of probiotic agent, 2 parts of konjac glucomannan, sodium alginate 2 parts, calcium chloride 2 parts.

[0029] Among them, the probiotic bacterial agent is formed by mixing Lactobacillus bulgaricus, Bifidobacterium and Streptococcus thermophilus at a weight ratio of 1:1.2:1.

[0030] A preparation method of a pharmaceutical composition for treating constipation, comprising the following steps:

[0031] (1) Take sodium alginate, add deionized water at 30°C, stir fully, and configure a sodium alginate solution with a concentration of 1%; take konjac glucomannan and add deionized water at 65°C, stir fully, and configure A konjac glucomannan solution with a concentration of 0.8%; the resulting konjac glucomannan solution is mixed with a sodium alginate solution, heated in a water bath at...

Embodiment 3

[0035] A pharmaceutical composition for treating constipation, which is made of the following raw materials in parts by weight: 3 parts of plantago polysaccharide, 9 parts of bee pollen, 2 parts of probiotic agent, 1 part of konjac glucomannan, sodium alginate 1 part, calcium chloride 2 parts.

[0036] Among them, the probiotic bacterial agent is formed by mixing Lactobacillus bulgaricus, Bifidobacterium and Streptococcus thermophilus with a weight ratio of 0.8:1:0.8.

[0037] A preparation method of a pharmaceutical composition for treating constipation, comprising the following steps:

[0038] (1) Take sodium alginate, add deionized water at 25°C, stir fully, and configure a sodium alginate solution with a concentration of 0.9%; take konjac glucomannan and add deionized water at 60°C, stir fully, and configure Concentration is 0.7% konjac glucomannan solution; the obtained konjac glucomannan solution is mixed with sodium alginate solution, heated in a water bath at a heatin...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a medicinal composition for treating constipation. The medicinal composition is prepared from the following raw materials in parts by weight: 3-4 parts of plantain seed polysaccharides, 8-10 parts of bee pollen, 2-4 parts of probiotic bacteria, 1-2 parts of konjac glucomannan, 1-2 parts of sodium alginate and 1-2 parts of calcium chloride. According to the medicinal composition, konjac glucomannan added into the composition can be used for promoting intestinal tract movement on the one hand, on the other hand, the konjac glucomannan can only be degraded by enzyme generated by partial bacteria in the large intestines, so that probiotics can be embedded by combination of the konjac glucomannan and sodium alginate, inactivation of probiotics in stomach can be avoided,and the effect of colonizing probiotics in intestinal tracts can be achieved; furthermore, the plantain seed polysaccharides, bee pollen, probiotic bacteria and konjac glucomannan are synergized to achieve the effects of softening excrement, promoting gastrointestinal motility and restoring intestinal flora balance, and the effect of radically treating constipation is achieved.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a pharmaceutical composition for treating constipation, a preparation method and application thereof. Background technique [0002] Constipation is a common digestive system disease in clinical practice, and it is a gastrointestinal functional abnormality caused by multiple factors. Generally, there are more women than men, and more elderly people than young adults. In recent years, with the acceleration of the pace of life in China, bad postures such as long-term sitting, coupled with changes in dietary structure and bad living habits such as staying up late, the incidence of constipation is on the rise. Long-term constipation can not only cause hemorrhoids, induce cardiovascular and cerebrovascular diseases, and increase the risk of colon cancer, but also cause patients to have bad emotions such as irritability, depression, and anxiety. [0003] At present, the commonly used...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K35/747A61P1/10A61K35/745A61K35/744A61K35/741A61K35/64A61K33/14A61K31/736A61K31/734A61K31/715
Inventor 尹芳
Owner 尹芳